Phantom study for CT artifacts of dental titanium implants and zirconia upper structures: the effects of occlusal plane angle setting and SEMAR algorithm.

OBJECTIVES: The single-energy metal artifact reduction (SEMAR) algorithm effectively reduces metal artifacts in computed tomography (CT). The study aimed to evaluate the effect of the occlusal plane angle on metal artifacts caused by dental implants and zirconia upper structures, and the effectiveness of SEMAR for CT prognostic evaluation. METHODS: Part of a bovine rib was used as the mandibular implant phantom. First, the phantom immersed in a water tank was scanned using CT to obtain the control image under certain conditions. Subsequently, three titanium implant bodies were implanted in a straight line into the phantom, and a zirconia superstructure was attached. CT scans were performed. The CT-reconstructed images were obtained with and without SEMAR processing. Twelve regions of interest (ROIs) were set at the same site on each sagittal image, and the CT values were measured at all the ROIs. The CT values of the ROIs in the control images and those of the ROIs with and without SEMAR were compared. RESULTS: The variations in the occlusal plane angle during CT imaging negligibly affected the number of regions in which metal artifacts appeared. SEMAR improved the CT value of the trabecular bone, which was affected by metal artifacts. CONCLUSION: This study showed that the occlusal plane angle occasionally did not affect the area of metal artifacts caused by dental implants or zirconia upper structures. Other results indicate that SEMAR is effective for accurately evaluating the alveolar bone around the implant body by reducing metal artifacts.

Oral intake of silica nanoparticles exacerbates intestinal inflammation.

Nanoparticles, i.e., particles with a diameter of ≤100 nm regardless of their composing material, are added to various foods as moisturizers, coloring agents, and preservatives. Silicon dioxide (SiO2, silica) nanoparticles in particular are widely used as food additives. However, the influence of SiO2 nanoparticle oral consumption on intestinal homeostasis remains unclear. The daily intake of 10-nm-sized SiO2 nanoparticles exacerbates dextran sulfate sodium (DSS)-induced colitis, whereas the daily intake of 30-nm-sized SiO2 nanoparticles has no influence on intestinal inflammation. The exacerbation of colitis induced by consuming 10-nm-sized SiO2 nanoparticles was abolished in mice deficient in apoptosis-associated speck-like protein containing a CARD (ASC). Our study indicates that the oral intake of small SiO2 nanoparticles poses a risk for worsening intestinal inflammation through activation of the ASC inflammasome.

Use of tungsten sheet as an alternative for reducing the radiation dose behind the digital imaging plate during intra-oral radiography.

OBJECTIVES: To verify the use of tungsten sheet as an alternative to lead foil for reducing the radiation dose behind storage phosphor plates (SPPs). METHODS: At six sites (incisor, canine, and molar sites in both the maxilla and mandible) in a head phantom, radiation doses were initially measured behind conventional film packets containing two films and a lead foil. At the same sites, radiation doses were also measured behind packets containing only SPPs. Thereafter, the same dose measurements were performed with shielding materials (lead foil or tungsten sheet) within the packets. These doses were defined as behind doses. RESULTS: There were no differences in the mean behind doses between the conventional film packets and the SPP packets without shielding materials for any of the six sites examined. The behind doses were reduced by both lead foil and tungsten sheet, with significant differences in all sites when compared with no shielding. Lead foil reduced the behind dose of the SPP packet to 37.6% on average, while tungsten sheet reduced the behind dose to less than 20% in all of the sites examined, with an average of 14.7%. CONCLUSIONS: Tungsten sheet appeared to be effective as an alternative shielding material, sufficiently reducing the doses behind the SPP packets to less than 20% when compared with sheetless packets in all of the six sites examined.

Great Saphenous Vein Flow Pattern as a Simple Ultrasonographic Sign of Early Recanalization of Deep Vein Thrombosis: A Case Series Report.

We retrospectively examined patients with ultrasonographically occlusive acute proximal deep vein thrombosis (DVT). All patients were categorized into two groups on the basis of whether great saphenous vein (GSV) flow toward the common femoral vein was detected (flow [+]; n=10) or undetected (flow [-]; n=10). We investigated the relationship between the GSV flow pattern and DVT recanalization. Thrombus recanalization, which is defined as diameter reduction to lower than 40% of the vessel diameter, was confirmed in seven of the flow (+), and none of the flow (-). This study proposes that the GSV flow pattern may be a simple marker for the recanalization of proximal occlusive DVT.

Protracted arthritis in a Japanese patient with familial Mediterranean fever.

The most common arthritic involvement in familial Mediterranean fever (FMF) is acute self- limiting monoarthritis which typically lasts for 72 h. Hip joint involvement is uncommon in FMF and can result either from a process specific to this disease or from a coexisting inflammatory joint disease. We describe a 37-year-old woman with FMF and right osteoarthritis secondary to congenital hip dislocation. Periodic fever with right coxalgia lasting for 6 months was treated using colchicine. Genetic analysis revealed homozygous mutation in the MEFV gene (L110P-E148Q/L110P-E148Q), confirming the FMF diagnosis. Although the clinical presentation and course of FMF arthritis are diverse, delineating these clinical patterns may help with early recognition and treatment to prevent destructive arthritis in FMF. Clinicians should consider the possibility of FMF development in unusual monoarthritis patients with recurrent febrile attacks.

Reduced induction of anti-PF4/heparin antibody in RA patients after total knee arthroplasty.

BACKGROUND: Heparin-induced thrombocytopenia is caused by antibodies (Abs) specific to platelet factor 4 (PF4)/heparin complexes. In this study, we evaluated the rates of seroconversion of anti-PF4/heparin Ab between patients with rheumatoid arthritis (RA) and with osteoarthritis (OA) who underwent total knee arthroplasty. METHODS: The subjects of this randomized controlled trial were 124 patients who underwent total knee arthroplasty (TKA) and received edoxaban with or without a foot pump as thromboprophylaxis. We measured anti-PF4/heparin Abs before and 10 days after surgery, as well as preoperative PF4, using commercially available ELISAs. We also used the database of J-PSVT, a hospital-based, prospective cohort study designed to document the effectiveness of thromboprophylactic agents during arthroplasty. RESULTS: The rates of seroconversion to anti-PF4/heparin Ab were lower in RA patients (4.0 %) than in OA patients (25.5 %). The anti-PF4/heparin IgG optical density (OD) values did not differ before and after surgery in RA patients. In contrast, there was a significant increase in anti-PF4/heparin IgG OD values in OA patients after TKA. In the J-PSVT data, the postoperative seroconversion rates of anti-PF4/heparin Ab were lower in RA patients (10.4 %) than in OA patients (21.8 %) who received fondaparinux. The titers of anti-CCP Ab were significantly lower in RA patients with postoperative ant-PF4/heparin Ab compared with those without postoperative ant-PF4/heparin Ab There was no significant difference in preoperative PF4 levels between RA patients and OA patients. The heparin-binding affinity of the circulating PF4 was similar between RA patients and OA patients; however, the IgG fractions isolated from the sera of RA patients contained PF4 more frequently (69.2 %) than those from OA patients (10.2 %). CONCLUSIONS: Our results showed a reduced likelihood of postoperative anti-PF/heparin Ab production in RA patients compared with OA patients. This suggests that the mechanisms underlying the anti-PF4 immune response in RA patients differ from the mechanisms of the anti-PF4/heparin immune response seen in OA patients after joint replacement. TRIAL REGISTRATION: ISRCTN 18090286. Registered 8 July 2016.

Effects of a Foot Pump on the Incidence of Deep Vein Thrombosis After Total Knee Arthroplasty in Patients Given Edoxaban: A Randomized Controlled Study.

We conducted a randomized clinical trial to compare the effectiveness of the A-V Impulse System foot pump for reducing the incidence of deep-vein thrombosis (DVT) after total knee arthroplasty (TKA) in patients under edoxaban thromboprophylaxis. Patients undergoing primary TKA at our institution between September 2013 and March 2015 were enrolled after obtaining informed consent. The patients were randomized to use the foot pump (n = 58) and not to use the foot pump (n = 62). Both groups were given prophylactic edoxaban. Primary outcomes were any DVT as detected by bilateral ultrasonography up to postoperative day 10 (POD10) and pulmonary embolism (PE) up to POD28. The safety outcomes were bleeding and death of any cause up to POD28. Plasma D-dimer levels were measured before TKA and on POD10 after TKA. Immunoglobulin G (IgG)-class anti-PF4/heparin antibodies were measured using an IgG-specific enzyme-linked immunosorbent assay. The incidences of any DVT up to POD28 were 31.0% and 17.7% in patients with or without the foot pump, respectively. The incidences of major bleeding up to POD28 were 5.1% and 4.8% in patients with or without the foot pump, respectively. Foot pump use did not significantly reduce the incidence of DVTs in patients undergoing TKA under edoxaban thromboprophylaxis. Although seroconversion of anti-PF4/heparin antibodies was confirmed in one-fourth of patients, the seroconversion rates did not differ between patients with (20.7%) or without (25.8%) foot pump use. This study shows that the A-V Impulse system foot pump did not affect the incidence of DVT under edoxaban thromboprophylaxis in patients undergoing TKA. Seroconversion of anti-PF4/heparin antibodies was detected in a significant number of patients who underwent TKA under antithrombotic prophylaxis using edoxaban.

Late cardiac effect of radiation therapy on a young woman with mediastinal Hodgkin's lymphoma.

We experienced an excision of the mediastinal tumor located in left anterior mediastinum found in a 21-year-old woman. The histologic diagnosis of Hodgkin's lymphoma was obtained. After operation, she was treated with mantle field radiotherapy (total 42 Gy) followed by chemotherapy. At 43-year old, she developed constrictive pericarditis and heart failure resulted in the late cardiac effects of mediastinal irradiation. Despite pericardiectomy followed by medical treatment, her cardiac symptoms gradually worsened and she died at 51-year old. At autopsy, her heart was smaller than normal person. The residual pericardium and the surface of the myocardium had fibrous degeneration with tight adhesion and thickness that were dominant at the right atrium and ventricle. Likewise, we demonstrated that pericardiectomy scarcely led to a favorable outcome in this patient. These facts might be based on the radiation-associated cardiac effects involving any components of the cardiac structure.

The Frequency of Fish-Eating Could Negatively Associate with Visceral Adiposity in Those Who Eat Moderately.

Visceral fat accumulation is regarded as one of the major phenotypes of metabolic syndrome. There have not been enough data on the relationship between the fish-eating habit and visceral adiposity. A total of 94 male participants received abdominal CT for the measurement of the visceral fat area (VFA), serum sampling for the fatty acid composition and questionnaires about their life-style. We divided the participants into two groups: whether they ate their fill (group F, n=70) or they ate in moderation (group M, n=24). Stepwise multiple linear regression analyses showed that usual alcohol consumption and lower daily physical activity in group F, and infrequent fish-eating and frequent fat-rich deserts in group M were the significant positive correlates with the VFA. The serum eicosapentaenoic acid (EPA)/arachidonic acid (AA) ratio showed significant correlation with the frequency of fish-eating in both groups. Interestingly, in group M, the serum EPA/AA ratio negatively correlated with the VFA, while it failed in group F. In conclusion, the present data suggest that the fish-eating habit might negatively associate with visceral fat accumulation only in those who are moderate in eating in the general population.

Risk of venous thromboembolism after total knee arthroplasty in patients with rheumatoid arthritis.

OBJECTIVE: To compare the incidence of venous thromboembolism (VTE) following total knee arthroplasty (TKA) between patients with rheumatoid arthritis (RA) and those with osteoarthritis (OA). METHODS: The subjects were composed of 1084 Japanese patients with OA and 204 with RA. Primary effectiveness outcomes were any deep vein thrombosis (DVT) as detected by bilateral ultrasonography up to postoperative Day 10 (POD10) and pulmonary embolism (PE) up to POD28. The main safety outcomes were bleeding and death from any cause up to POD28. Plasma D-dimer levels were measured before and at POD10 after TKA. RESULTS: The study cohort was composed of 1288 patients from 34 hospitals. There was no death up to POD28. PE occurred in 2 patients with OA and in no patients with RA. The incidence of primary effectiveness outcome was 24.3% and 24.0% in patients with OA and RA, respectively. The incidence of major bleeding up to POD28 was 1.3% and 0.5% in patients with OA and RA, respectively. No differences in the incidence of VTE (symptomatic/asymptomatic DVT plus PE) or bleeding were noted between patients with RA and OA. D-dimer levels on POD10 were significantly higher in patients with OA compared with those with RA. Also, D-dimer levels on POD10 were significantly lower in patients receiving fondaparinux than in patients without pharmacological prophylaxis. CONCLUSION: Despite some differences in demographic data, patients with RA and OA have equivalent risks of VTE and bleeding following TKA.

Secretion of salivary statherin is compromised in uncontrolled diabetic patients.

BACKGROUND: Statherin is an important salivary protein for maintaining oral health. The purpose of the current study was to determine if differences in statherin levels exist between diabetic and healthy subjects. METHODS: A total of 48 diabetic and healthy controls were randomly selected from a community-based database. Diabetic subjects (n=24) had fasting glucose levels >180 mg/dL, while controls (n=24) had levels <110 mg/dL. Parotid saliva (PS) and sublingual/submandibular saliva (SS) were collected and salivary flow rates determined. Salivary statherin levels were determined by densitometry of Western blots. Blood hemoglobin A1c (HbA1c) and total protein in saliva were also obtained. RESULTS: SS, but not PS, salivary flow rate and total protein in diabetics were significantly less than in healthy controls (p=0.021 & p<0.001 respectively). Correlation analysis revealed the existence of a negative correlation between PS statherin levels and HbA1c (p=0.012) and fasting glucose (p=0.021) levels, while no such correlation was found for SS statherin levels. When statherin levels were normalized to total salivary protein, the proportion of PS statherin, but not SS statherin, in diabetics was significantly less than controls (p=0.032). In contrast, the amount of statherin secretion in SS, but not PS, was significantly decreased in diabetics compared to controls (p=0.016). CONCLUSIONS AND GENERAL SIGNIFICANCE: The results show that synthesis and secretion of statherin is reduced in diabetics and this reduction is salivary gland specific. As compromised salivary statherin secretion leads to increased oral health risk, this study indicates that routine oral health assessment of these patients is warranted.

Role of intraoral color Doppler sonography in predicting delayed cervical lymph node metastasis in patients with early-stage tongue cancer: a pilot study.

OBJECTIVE: To clarify the intraoral color Doppler sonographic features of tongue cancer in relation to cervical lymph node metastasis. STUDY DESIGN: Thirty-one patients (24 men and 7 women; 32-87 years old; median 60.6 years) with T1-2 N0 squamous cell carcinoma of the tongue were enrolled. Preoperative clinical information and sonographic findings were collected. Patients were followed up for 2 years or more, and the presence of delayed lymph node metastasis was investigated. Significant clinical and sonographic factors were evaluated in relation to lymph node metastasis. RESULTS: Significant differences in maximum and minimum tumor size, clinical type, tumor depth and thickness, shape of the invading front of the tumor, vascular index (VI) of the tumor area, and asymmetry of the VI of the deep lingual artery were observed between patients with cervical lymph node metastasis and those without. The areas under the curve (AUCs) of tumor thickness and the VI of the tumor area were 0.861 and 0.909, respectively, on receiver operating characteristic (ROC) curve analysis for predicting lymph node metastasis. The AUC for the VI showed a slightly higher value, although the difference was not significant (P = .532). CONCLUSIONS: Intraoral color Doppler sonography is recommended, as it may identify predictive factors of cervical lymph node metastasis.

Measurement of cerebral blood volume dynamics during volitional swallowing using functional near-infrared spectroscopy: an exploratory study.

The aim of this study was to examine cerebral blood volume dynamics during volitional swallowing using multi-channel functional near-infrared spectroscopy (fNIRS) to understand the basic cortical activation patterns. Fifteen volunteers (age, 26.5±1.3 years, mean±SD) performed volitional swallowing of a 5-ml bolus of water as a task. A 52-channel fNIRS system was used for measuring oxy-Hb levels. We determined the oxy-Hb concentration changes in each channel by calculating the differences between rest and task oxy-Hb levels. Differences in rest and task data were assessed using a paired-t test (p<0.05). A significant increase in oxy-Hb was found in 21 channels. The cortical regions that exhibited increased oxy-Hb concentration included the bilateral precentral gyrus, postcentral gyrus, inferior frontal gyrus, superior temporal gyrus, middle temporal gyrus, and supramarginal gyrus. These data provide a description of cortical activation patterns during volitional swallowing using fNIRS, which will be useful for the evaluation of dysphasia and the effects of the rehabilitation [Corrected].

Experimental pain in the gingiva and its impact on prefrontal cortical hemodynamics: a functional near-infrared spectroscopy study.

Evaluating alterations in brain activity in response to pain stimulus can help understand the mechanisms underlying pain perception. We measured oxygenated hemoglobin (oxy-Hb) levels using functional near-infrared spectroscopy (fNIRS) in order to assess prefrontal cortex activation after inducing a pain stimulus to the gingiva. Twenty-three right-handed, healthy male subjects (mean age: 29.3±3.6 years) were subjected to a mild pain stimulus to the tissue around the right maxillary central incisor. The periodontal pain stimulus (PPS) was elicited from a pocket probe, and a multi-channel fNIRS system with its accompanying 22-channel probes was used for measuring oxy-Hb levels. Mean oxy-Hb levels for each channel were calculated on the basis of values obtained at rest and during the PPS load, for 1min each. The change in oxy-Hb level was calculated by subtracting oxy-Hb at rest from oxy-Hb levels during PPS load. Oxy-Hb levels in each channel during both conditions were then compared using the paired t-test and Bonferroni correction. Pain stimulation caused oxy-Hb levels to decrease in virtually all areas of the prefrontal cortex, particularly, in the superior frontal gyrus, the middle frontal gyrus, and the orbital part of the superior, middle, and inferior frontal gyrus, on the brain side contralateral to the pain load. This measurement could prove beneficial as an index for objective pain evaluation.

Serum eicosapentaenoic acid/arachidonic acid ratio is low in patients with pulmonary thromboembolism.

Recently n-3 polyunsaturated fatty acids (PUFAs) have been reported to play protective roles against cardiovascular diseases. Pulmonary thromboembolism (PTE) is one of the critical diseases in the circulatory system. However the relationship between n-3 PUFAs and PTE has not been reported. A total of 144 outpatients of the division of cardiology, including 12 of PTE cases, were enrolled in the present study and serum levels of eicosapentaenoic acid (EPA) and arachidonic acid (AA) were analyzed. We found that the EPA/AA ratio of the patients with PTE (the PTE group) was significantly lower than that of the patients without PTE (the non-PTE group) (p=0.007 for log EPA/log AA ratio). Next, the PTE group was divided into two groups by the presence or absence of malignant carcinoma. The PTE without carcinoma group showed significantly lower EPA/AA ratio than that of the non-PTE group (p=0.002 for log EPA/log AA ratio). However, the PTE with carcinoma group did not show the statistical difference in EPA/AA ratio compared with the non-PTE group (p=0.39). These data indicate that PTE may be associated with a low EPA/AA ratio, although the presence of malignant carcinoma should be taken into account.

Serum amyloid A triggers the mosodium urate -mediated mature interleukin-1ß production from human synovial fibroblasts.

BACKGROUND: Monosodium urate (MSU) has been shown to promote inflammasome activation and interleukin-1ß (IL-1ß) secretion in monocyte/macrophages, but the cellular pathway and nod-like receptor family, pyrin domain containing 3 (NLRP3) inflammasome activation in synovial tissues, remain elusive. In this study, we investigated the effects of MSU on synovial fibroblasts to elucidate the process of MSU-mediated synovial inflammation. METHODS: Human synovial fibroblasts were stimulated with MSU in the presence or absence of serum amyloid A (SAA). The cellular supernatants were analyzed by immunoblotting using anti-IL-1ß or anti-caspase-1 antibodies. IL-1ß or NLRP3 mRNA expressions were analyzed by real-time PCR or reverse transcription-PCR (RT-PCR) method. RESULTS: Neither SAA nor MSU stimulation resulted in IL-1ß or interleukin-1α (IL-1α) secretions and pro-IL-1ß processing in synovial fibroblasts. However, in SAA-primed synovial fibroblasts, MSU stimulation resulted in the activation of caspase-1 and production of active IL-1ß and IL-1α. The effect of SAA on IL-1ß induction was impaired in cells by silencing NLRP3 using siRNA or treating with caspase-1 inhibitor. In addition, SAA induced the secretion of cathepsin B and NLRP3 mRNA expression in synovial fibroblasts. CONCLUSIONS: Our data demonstrate that exposure of human synovial fibroblasts to SAA promotes MSU-mediated caspase-1 activation and IL-1ß secretion in the absence of microbial stimulation. These findings provide insight into the molecular processes underlying the synovial inflammatory condition of gout.

Clinical and dental computed tomographic evaluation 1 year after coronectomy.

PURPOSE: Coronectomy is performed when contact between the mandibular third molar apex and the inferior alveolar nerve is suspected. The efficacy of coronectomy compared with conventional tooth extraction has been recognized in recent years. However, few studies have reported the postoperative prognosis of roots remaining in the bone or surrounding tissue. Therefore, a clinical evaluation was performed with dental computed tomographic imaging of the coronectomy sites 1 year after the procedure. PATIENTS AND METHODS: This study investigated 101 patients (116 teeth) who underwent a coronectomy from March 2006 through December 2009. They were recalled 1 year later for a clinical evaluation and dental computed tomographic imaging of the coronectomy sites. The clinical evaluation was based on palpation and macroscopic findings. RESULTS: In 99.2% (115 teeth) of the studied cases, the soft tissue distal to the mandibular second molar was healthy and the retained roots were covered by bone. In 1 case (0.8%), an eruption of roots into the oral cavity was observed; however, no inflammation was observed in the nearby soft tissue. In all 116 teeth, no transmission images indicative of periapical lesions, which usually result from necrosis of the pulp, were observed in the apical area of the retained roots. CONCLUSIONS: The absence of transmission images indicative of periapical lesions and the presence of bone covering more than 99.2% (115 teeth) of the retained roots showed a safe postoperative course at the 1-year follow-up after coronectomy.

Masseter muscle sonographic features as indices for evaluating efficacy of massage treatment.

OBJECTIVE: The aim of this study was to clarify the sonographic features of the masseter muscle as indices for judging the efficacy of massage treatment. STUDY DESIGN: Fifteen patients with temporomandibular disorder (10 with unilateral and 5 with bilateral muscle pain) underwent massage treatment alternately on the bilateral masseter and temporal muscles with an oral rehabilitation robot. Sonography was performed before and after treatment, and the masseter thickness and existence of anechoic areas were evaluated. RESULTS: The thickness on the symptomatic side in the unilateral group significantly decreased after treatment. Anechoic areas were shown in 20 muscles (66.7%) before treatment, and disappeared or were reduced in size in 17 muscles (85.0%) after treatment. The pretreatment thickness was significantly related to visual analog scale (VAS) scores regarding posttreatment muscle pain and massage impression. The existence of anechoic areas was relevant to VAS scores regarding muscle pain. CONCLUSION: Masseter thickness and existence of anechoic areas might be related to the therapeutic efficacy regarding muscle pain.

Magnetic resonance T2-weighted IDEAL water imaging for assessing changes in masseter muscles caused by low-level static contraction.

OBJECTIVE: The aim of this study was to clarify the changes, using magnetic resonance (MR) images, in the masseter muscles caused by low-level static contraction. STUDY DESIGN: Ten healthy male volunteers were enrolled in the study. The MR scans were performed before, immediately after, and 10 minutes after low-level static contraction. Two imaging sequences were acquired: a diffusion-weighted image and an iterative decomposition of water and fat with echo asymmetry and least-squares estimation (IDEAL) image. The apparent diffusion coefficient (ADC), the signal-to-noise ratio (SNR), and the thicknesses of the right and left masseter muscles were examined. RESULTS: The ADC and SNR immediately after exercise were significantly higher than those before exercise and 10 minutes after exercise. The muscles were significantly thicker immediately after exercise than before exercise and 10 minutes after exercise. CONCLUSION: We confirmed the presence of edema in the masseter muscles caused by low-level static contraction using MR images.

Evaluation of correspondence of dental Computed Tomography imaging to anatomic observation of external root resorption.

Radiography using a compact dental CT, the 3D Accuitomo XYZ Slice View Tomograph (3D Accuitomo), was performed for examining the root resorption of a mandibular premolar in a patient who needed endodontic therapy. The images obtained by the 3D Accuitomo clearly showed the apparent presence of external root resorption of the tooth. As the root resorption had progressed seriously, the diagnosis was that it was impossible to save the tooth. After having obtained informed consent from the patient, the tooth was extracted. The surface of the root of the extracted tooth was examined visually without magnification, and the observations were compared with the findings made by 3D Accuitomo imaging for evaluating the reliability of the dental CT for diagnostic imaging of root resorption. The radiographic and visual examination results corresponded completely. Thus the 3D Accuitomo depicted the aspects of root resorption accurately; and its application for clinical use should be very effective for examining and diagnosing root resorption.