ABSTRACT
Titanium dioxide (TiO2) nanoparticles (NPs) have been doped with varying amounts (0.005, 0.010 and 0.015â¯M) of silver nanoparticles (Ag NPs) using hydrothermal method. Further, in this work, a green approach was followed for the formation of Ag@TiO2 NPs using Aloe vera gel as a capping and reducing agent. The structural property confirmed the presence of anatase phase TiO2. Increased peak intensity was observed while increasing the Ag concentration. Further, the morphological and optical properties have been studied, which confirmed the effective photocatalytic behavior of the prepared Ag@TiO2 NPs. The photocatalytic performance of Ag@TiO2 has been considered for the degradation of picric acid in the visible light region. The concentration at 0.010â¯M of the prepared Ag@TiO2 has achieved higher photocatalytic performance within 50â¯min, which could be attributed to its morphological behavior. Similarly, anticancer activity against lung cancer cell lines (A549) was also determined. The Ag@TiO2 NPs generated a large quantity of reactive oxygen species (ROS), resulting in complete cancer cell growth suppression after their systemic in vitro administration. Ag@TiO2 NPs was adsorbed visible light that leads to an enhanced anticancer sensitivity by killing and inhibiting cancer cell reproduction through cell viability assay test. It was clear that 0.015â¯M of Ag@TiO2 NPs were highly effective against human lung cancer cell lines and showed increased production of ROS in cancer cell lines due to the medicinal behavior of the Aloe vera gel.
Subject(s)
Antineoplastic Agents/chemistry , Metal Nanoparticles/chemistry , Silver/chemistry , Titanium/chemistry , A549 Cells , Aloe/chemistry , Aloe/metabolism , Antineoplastic Agents/chemical synthesis , Antineoplastic Agents/pharmacology , Catalysis , Cell Survival/drug effects , Green Chemistry Technology , Humans , Light , Metal Nanoparticles/toxicity , Picrates/chemistry , Plant Extracts/chemistry , Plant Leaves/chemistry , Plant Leaves/metabolism , Reactive Oxygen Species/metabolismABSTRACT
Silver nanoparticles (Ag NPs) were synthesized by solution combustion method using glycine and citric acid as fuels. The prepared Ag NPs were characterized by optical absorption spectroscopy, X-Ray Diffraction (XRD), High Resolution Transmission Electron Microscopy (HRTEM), Fourier Transform Infrared spectroscopy (FTIR) and Energy Dispersion Spectroscopic (EDS) techniques. Surface plasmon resonance peak was appeared at 410 and 418 nm for glycine (GAg) and citric acid (CAg) assisted silver nanoparticles respectively. The silver NPs are fcc in crystal structure. The calculated average particle size from XRD was found around 29 nm for GAg and 41 nm for CAg. HRTEM image shows that the silver nanoparticles have strain and fivefold symmetry formed by twinning in the crystal structure. The photocatalytic activity of TiO2 nanoparticles with Ag NPs were also elucidated and were found that the Ag NPs enhance the photocatalytic activity of TiO2.
Subject(s)
Light , Metal Nanoparticles/chemistry , Silver/chemistry , Titanium/chemistry , Absorption , Catalysis/radiation effects , Citric Acid/chemistry , Glycine/chemistry , Metal Nanoparticles/ultrastructure , Spectrometry, X-Ray Emission , Spectroscopy, Fourier Transform Infrared , Time Factors , X-Ray DiffractionABSTRACT
Copper oxide (CuO) nanoflowers were prepared by solution combustion method and glycine was used as fuel. The prepared nanoflowers are monoclinic in crystalline structure. FESEM and HRTEM studies confirmed the flower like structure of the CuO. The CuO nanoflowers were composed of wide nanopetals/sheets. CuO nanoflowers show very good photocatalytic activity. The apparent rate constant of this catalytic reaction was 0.016/min. The estimated direct band gap energy of the CuO was 3 eV.