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6.
Am J Dermatopathol ; 42(4): 244-250, 2020 Apr.
Article in English | MEDLINE | ID: mdl-31268926

ABSTRACT

In the past decades, there was a considerable advance in regard to recognition of morphologic findings and classification of several benign and malignant vascular proliferations. In 2002, attention was called by Requena et al to a new variant of cutaneous hemangioma named acquired elastotic hemangioma. In this article, a case of acquired elastotic hemangioma is reported with documentation of clinical, dermatoscopic, histopathological, and immunohistochemical findings. A systematic review of the previously 49 reported cases is provided. The criteria for clinical and histopathological diagnosis are highlighted.


Subject(s)
Elastic Tissue/pathology , Hemangioma/pathology , Skin Neoplasms/pathology , Female , Humans , Middle Aged
7.
An Bras Dermatol ; 94(2): 214-216, 2019.
Article in English | MEDLINE | ID: mdl-31090828

ABSTRACT

Onychocytic matricoma is a newly described tumor of the nail matrix. Clinically, it presents with localized thickening of the nail plate and melanonychia. Histologically, it represents a benign acanthoma of onychocytes. There are 8 cases reported in the literature. A 12-year-old girl presented with localized melanonychia and concurrent thickening of the nail plate restricted to the area of pigmentation affecting the right thumb, with no history of trauma or pain. We report a case of this rare tumor occurring in late childhood and provide a comprehensive review of its clinical presentation and differential diagnosis. Both clinicians and dermatopathologists should be aware of the presentation of onychocytic matricoma and include it in their scope of diagnosis of longitudinal nail bands.


Subject(s)
Acanthoma/pathology , Nail Diseases/pathology , Skin Neoplasms/pathology , Child , Diagnosis, Differential , Female , Humans , Nail Diseases/surgery , Skin Neoplasms/surgery , Thumb
8.
An. bras. dermatol ; An. bras. dermatol;94(2): 214-216, Mar.-Apr. 2019. tab, graf
Article in English | LILACS | ID: biblio-1001138

ABSTRACT

Abstract Onychocytic matricoma is a newly described tumor of the nail matrix. Clinically, it presents with localized thickening of the nail plate and melanonychia. Histologically, it represents a benign acanthoma of onychocytes. There are 8 cases reported in the literature. A 12-year-old girl presented with localized melanonychia and concurrent thickening of the nail plate restricted to the area of pigmentation affecting the right thumb, with no history of trauma or pain. We report a case of this rare tumor occurring in late childhood and provide a comprehensive review of its clinical presentation and differential diagnosis. Both clinicians and dermatopathologists should be aware of the presentation of onychocytic matricoma and include it in their scope of diagnosis of longitudinal nail bands.


Subject(s)
Humans , Female , Child , Skin Neoplasms/pathology , Acanthoma/pathology , Nail Diseases/pathology , Skin Neoplasms/surgery , Thumb , Diagnosis, Differential , Nail Diseases/surgery
11.
Am J Dermatopathol ; 40(6): e78-e79, 2018 Jun.
Article in English | MEDLINE | ID: mdl-29781866
12.
An Bras Dermatol ; 91(4): 514-6, 2016.
Article in English | MEDLINE | ID: mdl-27579751

ABSTRACT

Melanomas can arise either de novo (70%) or from pre-existing melanocytic lesions (30%). Of the latter, most cases arise at the dermoepidermal junction from small congenital or acquired non-blue nevi while only a few arise from blue nevi, notably the cellular subtype and less commonly the common (dendritic) type. Melanomas that arise from blue nevi usually occur on the scalp with greater frequency, as in the case described. Although previous studies have discussed melanoma arising from giant congenital blue nevi, few have discussed those arising from intermediate blue nevi. We present a case of a 52-yearold man with melanoma on the scalp evolving from an intermediate congenital common blue nevus.


Subject(s)
Head and Neck Neoplasms/pathology , Melanoma/pathology , Nevus, Blue/congenital , Nevus, Blue/pathology , Scalp/pathology , Skin Neoplasms/congenital , Skin Neoplasms/pathology , Biopsy , Dermis/pathology , Fatal Outcome , Humans , Male , Middle Aged
13.
An. bras. dermatol ; An. bras. dermatol;91(4): 514-516, July-Aug. 2016. graf
Article in English | LILACS | ID: lil-792443

ABSTRACT

Abstract: Melanomas can arise either de novo (70%) or from pre-existing melanocytic lesions (30%). Of the latter, most cases arise at the dermoepidermal junction from small congenital or acquired non-blue nevi while only a few arise from blue nevi, notably the cellular subtype and less commonly the common (dendritic) type. Melanomas that arise from blue nevi usually occur on the scalp with greater frequency, as in the case described. Although previous studies have discussed melanoma arising from giant congenital blue nevi, few have discussed those arising from intermediate blue nevi. We present a case of a 52-yearold man with melanoma on the scalp evolving from an intermediate congenital common blue nevus.


Subject(s)
Humans , Male , Middle Aged , Scalp/pathology , Skin Neoplasms/congenital , Nevus, Blue/congenital , Nevus, Blue/pathology , Head and Neck Neoplasms/pathology , Melanoma/pathology , Biopsy , Fatal Outcome , Dermis/pathology
14.
An Bras Dermatol ; 91(3): 345-9, 2016.
Article in English | MEDLINE | ID: mdl-27438203

ABSTRACT

Leprosy is a chronic disease characterized by manifestations in the peripheral nerves and skin. The course of the disease may be interrupted by acute phenomena called reactions. This article reports a peculiar case of type 2 leprosy reaction with Sweet's syndrome-like features as the first clinical manifestation of leprosy, resulting in a delay in the diagnosis due to unusual clinical presentation. The patient had clinical and histopathological features reminiscent of Sweet's syndrome associated with clusters of vacuolated histiocytes containing acid-fast bacilli isolated or forming globi. Herein, it is discussed how to recognize type 2 leprosy reaction with Sweet's syndrome features, the differential diagnosis with type 1 leprosy reaction and the treatment options. When this kind of reaction is the first clinical presentation of leprosy, the correct diagnosis might be not suspected clinically, and established only with histopathologic evaluation.


Subject(s)
Leprosy, Multibacillary/diagnosis , Sweet Syndrome/diagnosis , Adult , Erythema/diagnosis , Female , Histiocytes/pathology , Humans , Leprostatic Agents/therapeutic use , Leprosy, Multibacillary/complications , Leprosy, Multibacillary/drug therapy , Leprosy, Multibacillary/pathology , Neutrophils/pathology , Prednisone/therapeutic use , Sweet Syndrome/drug therapy , Sweet Syndrome/etiology , Sweet Syndrome/pathology , Thalidomide/therapeutic use
15.
An. bras. dermatol ; An. bras. dermatol;91(3): 345-349, tab, graf
Article in English | LILACS | ID: lil-787306

ABSTRACT

Abstract Leprosy is a chronic disease characterized by manifestations in the peripheral nerves and skin. The course of the disease may be interrupted by acute phenomena called reactions. This article reports a peculiar case of type 2 leprosy reaction with Sweet's syndrome-like features as the first clinical manifestation of leprosy, resulting in a delay in the diagnosis due to unusual clinical presentation. The patient had clinical and histopathological features reminiscent of Sweet's syndrome associated with clusters of vacuolated histiocytes containing acid-fast bacilli isolated or forming globi. Herein, it is discussed how to recognize type 2 leprosy reaction with Sweet's syndrome features, the differential diagnosis with type 1 leprosy reaction and the treatment options. When this kind of reaction is the first clinical presentation of leprosy, the correct diagnosis might be not suspected clinically, and established only with histopathologic evaluation.


Subject(s)
Humans , Female , Adult , Sweet Syndrome/diagnosis , Leprosy, Multibacillary/diagnosis , Thalidomide/therapeutic use , Prednisone/therapeutic use , Sweet Syndrome/etiology , Sweet Syndrome/pathology , Sweet Syndrome/drug therapy , Erythema/diagnosis , Leprosy, Multibacillary/complications , Leprosy, Multibacillary/pathology , Leprosy, Multibacillary/drug therapy , Histiocytes/pathology , Leprostatic Agents/therapeutic use , Neutrophils/pathology
16.
An Bras Dermatol ; 91(1): 80-3, 2016.
Article in English | MEDLINE | ID: mdl-26982783

ABSTRACT

Cytomegalovirus is an opportunistic virus that commonly affects immunosuppressed patients. Cutaneous involvement by this virus is rare and occurs in significantly immunocompromised hosts, with a poor prognosis. Skin ulcers may represent the first sign of systemic infection by cytomegalovirus in these patients. Herein, a case of a systemic infection by Cytomegalovirus presenting as genital and oral ulcers in a kidney-transplant recipient is reported.


Subject(s)
Cytomegalovirus Infections/pathology , Immunocompetence , Kidney Transplantation/adverse effects , Skin Diseases, Viral/pathology , Aged , Cytomegalovirus Infections/immunology , Humans , Male , Polymerase Chain Reaction , Skin Diseases, Viral/immunology , Skin Ulcer/pathology , Skin Ulcer/virology
17.
An. bras. dermatol ; An. bras. dermatol;91(1): 80-83, Jan.-Feb. 2016. graf
Article in English | LILACS | ID: lil-776415

ABSTRACT

Abstract Cytomegalovirus is an opportunistic virus that commonly affects immunosuppressed patients. Cutaneous involvement by this virus is rare and occurs in significantly immunocompromised hosts, with a poor prognosis. Skin ulcers may represent the first sign of systemic infection by cytomegalovirus in these patients. Herein, a case of a systemic infection by Cytomegalovirus presenting as genital and oral ulcers in a kidney-transplant recipient is reported.


Subject(s)
Aged , Humans , Male , Cytomegalovirus Infections/pathology , Immunocompetence , Kidney Transplantation/adverse effects , Skin Diseases, Viral/pathology , Cytomegalovirus Infections/immunology , Polymerase Chain Reaction , Skin Diseases, Viral/immunology , Skin Ulcer/pathology , Skin Ulcer/virology
18.
An Bras Dermatol ; 90(3): 407-10, 2015.
Article in English | MEDLINE | ID: mdl-26131876

ABSTRACT

Milker's nodule is an occupational viral skin disease of universal distribution, caused by the Paravaccinia virus and that occurs in individuals who deal with dairy cattle herds. We describe a case acquired due to lack of use of PPE (Personal Protective Equipment) and perform a literature review.


Subject(s)
Hand Dermatoses/pathology , Occupational Diseases/pathology , Poxviridae Infections/pathology , Skin Diseases, Viral/pathology , Animals , Biopsy , Cattle , Disease Progression , Female , Humans , Middle Aged , Pseudocowpox Virus
19.
An. bras. dermatol ; An. bras. dermatol;90(3): 407-410, May-Jun/2015. tab, graf
Article in English | LILACS | ID: lil-749672

ABSTRACT

Abstract Milker's nodule is an occupational viral skin disease of universal distribution, caused by the Paravaccinia virus and that occurs in individuals who deal with dairy cattle herds. We describe a case acquired due to lack of use of PPE (Personal Protective Equipment) and perform a literature review.


Subject(s)
Humans , Animals , Female , Middle Aged , Cattle , Skin Diseases, Viral/pathology , Poxviridae Infections/pathology , Hand Dermatoses/pathology , Occupational Diseases/pathology , Biopsy , Pseudocowpox Virus , Disease Progression
20.
RBM rev. bras. med ; RBM rev. bras. med;71(n.esp.g3)ago. 2014.
Article in Portuguese | LILACS | ID: lil-750821

ABSTRACT

Doença rara, descrita por Pinkus em 1957, a alopecia mucinosa pertence às alopecias cicatriciais. É assim denominada pelo acúmulo de mucina e linfócitos na porção infundibular do aparelho pilossebáceo, promovendo destruição total e irreversível do local afetado. De etiologia desconhecida, clinicamente se manifesta em placas, geralmente normocrômicas, bem demarcadas, composta por pápulas com evidente proeminência folicular. A ausência de sintomas é a regra. Sua classificação como micose fungoide incipiente ainda não é consenso. Com pico bimodal de incidência costuma manifestar-se em crianças ou idosos, através de diferentes quadros clínicos, prognósticos e associações. Não existem, até o presente momento, estudos de dermatoscopia nessa rara entidade. Descrevemos uma apresentação atípica da doença e propomos seus achados dermatoscópicos.

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