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Nat Prod Res ; 35(9): 1491-1496, 2021 May.
Article in English | MEDLINE | ID: mdl-31429297

ABSTRACT

A phytochemical investigation on the whole plant of Plantago maxima Juss. ex Jacq led to the isolation of a new and rare chlorinated iridoid glycoside named plantomoside (1), along with three known compounds, geniposidic acid (2), 10-deoxygeniposidic acid (3), and viteoid II (4). The structure of 1 was determined through 1 D and 2 D NMR spectroscopic data analysis, HR-ESI-MS, and acid hydrolysis.


Subject(s)
Chlorine/chemistry , Iridoid Glycosides/isolation & purification , Plantago/chemistry , Animals , Cell Death/drug effects , Cell Line, Tumor , Humans , Iridoid Glucosides/chemistry , Iridoid Glucosides/isolation & purification , Iridoid Glycosides/chemistry , Iridoid Glycosides/pharmacology , Lipopolysaccharides/pharmacology , Mice , Nitric Oxide/biosynthesis , Phytochemicals/chemistry , Phytochemicals/isolation & purification , Phytochemicals/pharmacology , RAW 264.7 Cells
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