ABSTRACT
We present a rare case of a 25-year-old woman with rheumatic heart disease who developed a superior mesenteric artery pseudoaneurysm (SMAPA) following infective endocarditis (IE). Initially, she presented with chest pain, dyspnea, and fever, leading to the diagnosis of IE and severe mitral regurgitation. After six weeks of antimicrobial therapy, she developed persistent abdominal pain. Further evaluation revealed a mycotic SMAPA, which was successfully treated with open surgical repair. Postoperatively, her abdominal pain improved significantly, and she was discharged on postoperative day five. The current case underscores the importance of maintaining a high index of suspicion for mycotic pseudoaneurysms in patients with risk factors, even when they present with nonspecific symptoms. The findings also highlight the critical role of computed tomography angiography (CTA) in accurate diagnosis and preoperative planning. The favorable outcome supports current guidelines for managing mycotic SMA pseudoaneurysms in complex scenarios, emphasizing the need for adherence to established protocols and recommendations.