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ACS Appl Mater Interfaces ; 10(51): 44678-44685, 2018 Dec 26.
Article in English | MEDLINE | ID: mdl-30489065

ABSTRACT

Real-time temperature monitoring of individual blood packages capable of wireless data transmission to ensure the safety of blood samples and minimize wastes has become a critical issue in recent years. In this work, we propose flexible temperature sensors using silver nanowires (NWs) and a flexible colorless polyimide (CPI) film integrated with a wireless data transmission circuit. The unique design of the temperature sensors was achieved by patterning Ag NWs using a three-dimensional printed mold and embedding the patterned Ag NWs in the CPI film (p-Ag NWs/CPI), which resulted in a flexible temperature sensor with electrical, mechanical, and temperature stability for applications in blood temperature monitoring. Indeed, a reliable resistance change of the p-Ag NWs/CPI was observed in the temperature range of -20 to 20 °C with a robust bending stability of up to 5000 cycles at 5 mm bending radius. Real-time and wireless temperature monitoring using the p-Ag NWs/CPI was demonstrated with the packages of rat blood. The result revealed that the stable and consistent temperature monitoring of individual blood packages could be achieved in a blood box, which was mainly attributed to the conformal attachment of the p-Ag NWs/CPI to different packages in a blood container.


Subject(s)
Blood , Metal Nanoparticles/chemistry , Nanowires/chemistry , Silver , Thermometry , Wireless Technology , Animals , Rats , Rats, Sprague-Dawley , Silver/chemistry , Silver/pharmacology , Temperature , Thermometry/instrumentation , Thermometry/methods
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