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Planta Med ; 64(3): 237-41, 1998 Apr.
Article in English | MEDLINE | ID: mdl-9581522

ABSTRACT

Roots of Nepenthes thorelii yielded plumbagin, 2-methylnaphthazarin, octadecyl caffeate, isoshinanolone, and droserone. In addition, seven derivatives were prepared from plumbagin. Each of these natural and semisynthetic compounds was evaluated for in vitro antimalarial potential.


Subject(s)
Antimalarials/chemistry , Naphthoquinones/chemistry , Plant Extracts/chemistry , Animals , Antimalarials/pharmacology , Drug Evaluation, Preclinical , Naphthoquinones/pharmacology , Plant Extracts/pharmacology , Plant Roots , Plasmodium falciparum/drug effects
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