Subject(s)
Lichen Planus/diagnosis , Scalp/pathology , Biopsy , Extremities , Humans , Lichen Planus/pathology , Male , Middle AgedABSTRACT
Actinic keratosis (AK) is a common dermatologic condition resulting from long-term sun exposure. It is considered a precancerous lesion that may convert into a squamous cell carcinoma, which highlights the importance of prompt identification, early treatment and eradication of AK, and recurrence monitoring. Currently, there are many treatments available for widespread AKs that include a combination of local lesion destruction along with stimulation of an individual's immune response. Preliminary data from combination therapy studies demonstrate that these may offer improved efficacy, tolerability, and long-term results compared with monotherapy. The authors investigate combination systems aimed at intensifying photodynamic therapy for the treatment of AKs as reported at the 8th World Congress of the International Academy of Cosmetic Dermatology in Cancun, Mexico, and include a comprehensive literature review. Further investigations and data collection are in progress in order to solidify these promising results.
Subject(s)
Dermatologic Agents/therapeutic use , Keratosis, Actinic/therapy , Photochemotherapy/methods , Combined Modality Therapy , Dermatologic Agents/administration & dosage , Dermatologic Agents/adverse effects , Humans , Keratosis, Actinic/pathology , Laser Therapy/adverse effects , Laser Therapy/methods , Photochemotherapy/adverse effects , Photosensitizing Agents/administration & dosage , Photosensitizing Agents/adverse effects , Photosensitizing Agents/therapeutic useSubject(s)
Conjunctival Diseases/etiology , Erythema/etiology , Leukemia, Prolymphocytic, T-Cell/pathology , Leukemic Infiltration/pathology , Erythema/pathology , Fatal Outcome , Female , Humans , Leukemia, Prolymphocytic, T-Cell/complications , Leukemia, Prolymphocytic, T-Cell/drug therapy , Leukemic Infiltration/complications , Middle AgedABSTRACT
Netherton syndrome (NS) is a rare congenital ichthyosis that is characterized by impaired skin barrier function. Topical medications are cautiously used in NS since toxicity from systemic absorption is a major concern. Narrowband ultraviolet B phototherapy is an alternative therapeutic option that demonstrated its beneficial and practical use in a patient with NS.