ABSTRACT
This case report describes a woman in her 30s who presented with a 3-year history of antiPL-12 antisynthetase syndrome characterized by interstitial lung disease, arthritis, and myositis and was diagnosed with antisynthetase syndromeassociated panniculitis.
Subject(s)
Myositis , Nitriles , Panniculitis , Pyrazoles , Pyrimidines , Humans , Myositis/diagnosis , Myositis/drug therapy , Antibodies, Antinuclear , Panniculitis/diagnosis , Panniculitis/drug therapy , Genes, T-Cell Receptor , AutoantibodiesABSTRACT
Spider bites represent an unusual and potentially over-represented clinical diagnosis. Despite a common fear of spiders, known as arachnophobia, current knowledge suggests that only a small number of families within the order Araneae are medically relevant. Moreover, most cutaneous spider reactions, including both evenomations and physical trauma, produce mild, local symptoms which may be managed with supportive care alone. The differential diagnosis for spider bites may be broad, especially if the offending arachnid is not seen or found. We describe a series of spiders relevant to the dermatologist in the United States.