ABSTRACT
The authors present the case of a nulliparous 34-year-old patient. At the tenth week of gestation, she developed phlebothrombosis of veins of the right leg and massive pulmonary embolism. After thrombolytic and heparin therapy she developed rethrombosis and heparin-induced thrombocytopenia type II. Lepirudin was introduced in therapy and in the 12th week of gestation acenocumarol was added. After the 34th week, she received danaparoid sodium. After a week, by cesarean section, a healthy and mature female was delivered.
Subject(s)
Heparin/adverse effects , Pregnancy Complications/etiology , Pregnancy Outcome , Pulmonary Embolism/complications , Pulmonary Embolism/drug therapy , Thrombocytopenia/etiology , Acenocoumarol/administration & dosage , Adult , Anticoagulants , Cesarean Section , Chondroitin Sulfates , Dermatan Sulfate , Female , Fibrinolytic Agents , Gestational Age , Heparitin Sulfate , Hirudins/administration & dosage , Humans , Pregnancy , Pregnancy Complications/drug therapy , Recombinant Proteins/administration & dosage , Thrombocytopenia/drug therapy , Venous Thrombosis/complications , Venous Thrombosis/drug therapyABSTRACT
Breast cancer is the leading cause of mortality among women aged 25 to 44 years in Serbia. The purpose of this study was to determine basic clinical and radiological features of breast cancer in young women. 93 women aged 31.0 +/- 3.5 years with breast cancer were identified. The analysis included clinical characteristics (TNM classification) and radiological features (mammography and breast ultrasound). 53.8% of the patients had locoregional disease. The mean diameter of breast cancer was 2.6 +/- 6 cm. Carcinoma in situ was found in 2.2%. Mammography was performed in 25.8% of the patients and breast ultrasound in 68.8%. The results of our study indicate that the diagnosis of breast cancer in young women is late, in the stage with palpable breast tumor and lymph node metastases. Mammography or breast ultrasound are not routinely used. The implementation of algorithms for breast cancer detection and diagnosis in young women helps in earlier detection of breast cancer and consequently improves outcomes.