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1.
Surg Obes Relat Dis ; 10(2): 313-21, 2014.
Article in English | MEDLINE | ID: mdl-24462305

ABSTRACT

BACKGROUND: Rapid weight loss after bariatric surgery is associated with gallstone formation, and cholecystectomy is required in up to 15% of patients. Prophylactic cholecystectomy or prophylactic ursodiol administration in the postoperative period have been suggested to address this problem. The objectives of this study were to investigate the frequency and timing of cholecystectomies after bariatric surgery and to determine the associated risk factors in patients who underwent laparoscopic Roux-en-Y gastric bypass (LRYGB), laparoscopic adjustable gastric band (LAGB), or laparoscopic sleeve gastrectomy (LSG). METHODS: Data prospectively collected in an institutional database were analyzed. Differences among the 3 procedures and the effects of ursodiol administration, patient demographic characteristics, postoperative weight loss, and individual surgeon practices on cholecystectomy rates were examined. Survival analysis and proportional hazard models were used. RESULTS: Of 1398 patients, 109 (7.8%) underwent cholecystectomy with a median follow-up of 49 (range 12-103) months. Cholecystectomy frequency was 10.6% after LRYGB, significantly higher than 2.9% after LAGB (P < .001), and 3.5% after LSG (P = .004). The frequency was highest within the first 6 months (3.7%), but declined over time to < 1% per year after 3 years. Ursodiol administration did not affect cholecystectomy rates (P = .97), and significant intersurgeon variability was noted. Excess weight loss (EWL)>25% within the first 3 months was the strongest predictor of postoperative cholecystectomy (P<.001). Cox hazards model revealed 1.25 odds ratio per 10% EWL within 3 months, and odds ratio .77 per decade of life. In addition, white patients had 1.45 times higher cholecystectomy rates than did black patients. Preoperative body mass index, gender, and surgeon did not affect cholecystectomy rates. CONCLUSION: Bariatric surgery is associated with a low frequency of postoperative cholecystectomy, which is highest early after surgery and mainly determined by the amount of EWL within the first 3 months. The results of the present study do not support routine prophylactic cholecystectomy at the time of bariatric surgery in asymptomatic patients.


Subject(s)
Bariatric Surgery/adverse effects , Cholecystectomy/statistics & numerical data , Gallstones/surgery , Obesity, Morbid/surgery , Adult , Female , Follow-Up Studies , Gallstones/epidemiology , Gallstones/etiology , Humans , Incidence , Male , Postoperative Complications , Prospective Studies , Risk Factors , Survival Rate/trends , United States/epidemiology
3.
J Vasc Surg ; 52(4): 1052-7, 2010 Oct.
Article in English | MEDLINE | ID: mdl-20888534

ABSTRACT

Blunt cerebrovascular injuries, defined as blunt injuries to the internal carotid or vertebral arteries, are uncommon and usually occur in victims of high-speed deceleration motor vehicle crashes. A blunt cerebrovascular injury after an equestrian accident is an extremely unusual presentation. In recent years, advances in screening and treatment with pharmacologic anticoagulation before the onset of neurologic symptoms have improved outcomes for these patients. Endovascular stenting and embolization, although unproven, offer a new potential approach for these complex injuries. We present a unique case of four-vessel blunt cerebrovascular injuries after a horse-riding injury that required multidisciplinary management.


Subject(s)
Athletic Injuries/complications , Carotid Artery, Internal, Dissection/etiology , Horses , Thoracic Injuries/complications , Vertebral Artery Dissection/etiology , Wounds, Nonpenetrating/complications , Animals , Anticoagulants/therapeutic use , Athletic Injuries/diagnostic imaging , Athletic Injuries/therapy , Brain Ischemia/etiology , Carotid Artery, Internal, Dissection/diagnostic imaging , Carotid Artery, Internal, Dissection/therapy , Combined Modality Therapy , Embolization, Therapeutic , Female , Humans , Magnetic Resonance Angiography , Middle Aged , Platelet Aggregation Inhibitors/therapeutic use , Stents , Stroke/etiology , Thoracic Injuries/diagnostic imaging , Thoracic Injuries/therapy , Tomography, X-Ray Computed , Treatment Outcome , Vertebral Artery Dissection/diagnostic imaging , Vertebral Artery Dissection/therapy , Wounds, Nonpenetrating/diagnostic imaging , Wounds, Nonpenetrating/therapy
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