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Six-Month Response to Delamanid Treatment in MDR TB Patients.

Hewison, Cathy; Ferlazzo, Gabriella; Avaliani, Zaza; Hayrapetyan, Armen; Jonckheere, Sylvie; Khaidarkhanova, Zarema; Mohr, Erika; Sinha, Animesh; Skrahina, Alena; Vambe, Debrah; Vasilyeva, Irina; Lachenal, Nathalie; Varaine, Francis.

Emerg Infect Dis ; 23(10)2017 10.

Article in English | MEDLINE | ID: mdl-28767036

ABSTRACT

Delamanid, recently available for the treatment of multidrug-resistant tuberculosis (MDR TB), has had limited use outside clinical trials. We present the early treatment results for 53 patients from 7 countries who received a delamanid-containing treatment for MDR TB. Results show good tolerability and treatment response at 6 months.

Subject(s)

Antitubercular Agents/therapeutic use , Nitroimidazoles/therapeutic use , Oxazoles/therapeutic use , Tuberculosis, Multidrug-Resistant/drug therapy , Adolescent , Female , HIV Infections/complications , Hepatitis C/complications , Humans , Male , Retrospective Studies , Tuberculosis, Multidrug-Resistant/complications

Compassionate use of new drugs in children and adolescents with multidrug-resistant and extensively drug-resistant tuberculosis: early experiences and challenges.

Tadolini, Marina; Garcia-Prats, Anthony J; D'Ambrosio, Lia; Hewison, Catherine; Centis, Rosella; Schaaf, H Simon; Marais, Ben J; Ferreira, Hannetjie; Caminero, Jose A; Jonckheere, Sylvie; Sinha, Animesh; Herboczek, Krzysztof; Khaidarkhanova, Zarema; Hayrapetyan, Armen; Khachatryan, Naira; Urtkmelidze, Ia; Loreti, Carolina; Esposito, Susanna; Matteelli, Alberto; Furin, Jennifer; Varaine, Francis; Migliori, Giovanni Battista.

Eur Respir J ; 48(3): 938-43, 2016 09.

Article in English | MEDLINE | ID: mdl-27338197

Subject(s)

Antitubercular Agents/therapeutic use , Compassionate Use Trials , Extensively Drug-Resistant Tuberculosis/drug therapy , Adolescent , Child , Extensively Drug-Resistant Tuberculosis/diagnosis , Female , Humans , Male , Treatment Outcome

ABSTRACT

Subject(s)

Subject(s)

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