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1.
Curr Probl Diagn Radiol ; 53(5): 570-575, 2024.
Article in English | MEDLINE | ID: mdl-38705772

ABSTRACT

RATIONAL AND OBJECTIVE: Diversity, equity, inclusion, and representation in various sectors have garnered increasing attention in the past two decades, including healthcare. In this report we investigate representation of females and underrepresented minorities (URM) in the field of radiology and asses for significant growth trends in representation in residency training programs in the United States. MATERIALS AND METHODS: De-identified trainee demographic information for active radiology trainees from 2016 to 2021 was queried using the Accreditation Council for Graduate Medical Education (ACGME), and new radiology trainees using the National Resident Matching Program (NRMP)'s Main Residency Match Data and Reports databooks. RESULTS: In 2021 females represented 26.7% of DR residency trainees and 22% of IR integrated trainees. In the same year URM trainees represented 11.3% of trainees and 8.7% of IR integrated trainees. From 2017 to 2021, diagnostic radiology had a compound average growth rate (CAGR) 1% (p <0.01) of female representation and 1.12% (p<0.01) of URM representation. CONCLUSION: This study quantifies female and underrepresented minority representation among radiology trainees for diagnostic radiology and radiology subspecialities, identifying modest uptrends in representation within both demographics.


Subject(s)
Education, Medical, Graduate , Internship and Residency , Minority Groups , Radiology , Humans , Female , Radiology/education , United States , Minority Groups/statistics & numerical data , Internship and Residency/statistics & numerical data , Physicians, Women/statistics & numerical data
2.
Nutr Res ; 124: 94-110, 2024 Apr.
Article in English | MEDLINE | ID: mdl-38430822

ABSTRACT

Anti-inflammatory activities of catechin-rich green tea extract (GTE) in obese rodents protect against metabolic endotoxemia by decreasing intestinal permeability and absorption of gut-derived endotoxin. However, translation to human health has not been established. We hypothesized that GTE would reduce endotoxemia by decreasing gut permeability and intestinal and systemic inflammation in persons with metabolic syndrome (MetS) compared with healthy persons. A randomized, double-blind, placebo-controlled, crossover trial in healthy adults (n = 19, 34 ± 2 years) and adults with MetS (n = 21, 40 ± 3 years) examined 4-week administration of a decaffeinated GTE confection (890 mg/d total catechins) on serum endotoxin, intestinal permeability, gut and systemic inflammation, and cardiometabolic parameters. Compared with the placebo, the GTE confection decreased serum endotoxin (P = .023) in both healthy persons and those with MetS, while increasing concentrations of circulating catechins (P < .0001) and γ-valerolactones (P = .0001). Fecal calprotectin (P = .029) and myeloperoxidase (P = .048) concentrations were decreased by GTE regardless of health status. Following the ingestion of gut permeability probes, urinary lactose/mannitol (P = .043) but not sucralose/erythritol (P > .05) was decreased by GTE regardless of health status. No between-treatment differences (P > .05) were observed for plasma aminotransferases, blood pressure, plasma lipids, or body mass nor were plasma tumor necrosis factor-α, interleukin-6, or the ratio of lipopolysaccharide-binding protein/soluble cluster of differentiation-14 affected. However, fasting glucose in both study groups was decreased (P = .029) by the GTE confection compared with within-treatment arm baseline concentrations. These findings demonstrate that catechin-rich GTE is effective to decrease circulating endotoxin and improve glycemic control in healthy adults and those with MetS, likely by reducing gut inflammation and small intestinal permeability but without affecting systemic inflammation.


Subject(s)
Acute-Phase Proteins , Blood Glucose , Carrier Proteins , Catechin , Cross-Over Studies , Endotoxins , Inflammation , Membrane Glycoproteins , Metabolic Syndrome , Permeability , Plant Extracts , Tea , Humans , Metabolic Syndrome/drug therapy , Double-Blind Method , Endotoxins/blood , Adult , Male , Female , Plant Extracts/pharmacology , Tea/chemistry , Catechin/pharmacology , Catechin/analogs & derivatives , Catechin/administration & dosage , Inflammation/drug therapy , Inflammation/blood , Blood Glucose/metabolism , Blood Glucose/drug effects , Endotoxemia/drug therapy , Fasting , Middle Aged , Intestinal Mucosa/metabolism , Intestinal Mucosa/drug effects , Camellia sinensis/chemistry
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