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1.
ACS Appl Mater Interfaces ; 11(18): 16951-16957, 2019 May 08.
Article in English | MEDLINE | ID: mdl-31034198

ABSTRACT

Wearable and skin-attachable electronics with portable/wearable and stretchable smart sensors are essential for health-care monitoring devices or systems. The property of adhesion to the skin in both dry and wet environments is strongly required for efficient monitoring of various human activities. We report here a facile, low-cost, scalable fabrication method for skin-adhesive graphene-coated fabric (GCF) sensors that are sensitive and respond fast to applied pressure and strain. With octopus-like patterns formed on the side of the GCF that touches the skin, the GCF adheres strongly to the skin in both dry and wet environments. Using these characteristics, we demonstrate efficient monitoring of a full range of human activities, including human physiological signals such as wrist pulse and electrocardiography (ECG), as well as body motions and speech vibrations. In particular, both measurements of ECG and wrist-bending motions were demonstrated even in wet conditions. Our approach has opened up a new possibility for wearable and skin-adherent electronic fabric sensors working even in wet environments for health-care monitoring and medical applications in vitro and in vivo.


Subject(s)
Biosensing Techniques , Graphite/chemistry , Monitoring, Physiologic/methods , Wearable Electronic Devices , Activities of Daily Living , Adhesives/chemistry , Electrocardiography/methods , Humans , Motion , Pulse , Speech/physiology , Water/chemistry
2.
Bioengineered ; 8(1): 99-104, 2017 Jan 02.
Article in English | MEDLINE | ID: mdl-27775502

ABSTRACT

Glucose concentration is closely related to the metabolic activity of cells and it is the most important substance as the energy source of a living body which plays an important role in the human body. This paper proposes an optical method that can measure the concentration of glucose. The change in glucose concentration was observed by using CIE diagram, and wavelength and purity values were detected. Also, even small changes in glucose concentration can be evaluated through mathematical modeling. This system is simple, economical, and capable of quantifying optical signals with numerical values for glucose sensing. This method can be applicable to the clinical field that examines diabetes mellitus or metabolic syndrome.


Subject(s)
Color , Colorimetry/methods , Glucose/analysis , Optics and Photonics , Models, Theoretical
3.
Technol Health Care ; 24 Suppl 2: S697-705, 2016 Apr 29.
Article in English | MEDLINE | ID: mdl-27259083

ABSTRACT

BACKGROUND: Lasers are advantageous in some applications to stimulate a small target area and is used in various fields such as optogenetic, photoimmunological and neurophysiological studies. OBJECTIVE: This study aims to implement a non-contact sense of touch without damaging biological tissues using laser. METHODS: Various laser parameters were utilized in safety range to induce a sense of touch and investigate the human responses. With heat distribution simulation, the amount of changes in the temperature and the tendency in laser parameters of sensory stimulation were analyzed. RESULTS: The results showed the identified tactile responses in safety range with various laser parameters and temperature distribution for the laser stimulus was obtained through the simulation. CONCLUSIONS: This study can be applied to the areas of sensory receptor stimulation, neurophysiology and clinical medicine.


Subject(s)
Lasers , Perception , Skin Temperature , Female , Humans , Male , Touch
4.
IEEE Trans Haptics ; 9(4): 574-585, 2016.
Article in English | MEDLINE | ID: mdl-27214916

ABSTRACT

In this paper, we demonstrate that a laser irradiated on a thin light-absorbing elastic medium attached on the skin can elicit a tactile sensation of mechanical tap. First, we present simulation results that show laser irradiation to the elastic medium creates inner elastic waves on the basis of thermoelastic effects and these elastic waves trigger the bending deformation of the medium, which then stimulates the skin. Second, we analyze the physical properties of the associated stimulus by measuring its force profile. Third, we identify the perceptual characteristics of the stimulus in comparison to those of mechanical and electrical stimuli by means of a perceptual experiment employing dissimilarity rating. All the evidence indicates that indirect laser radiation provides a sensation of short mechanical tap. Furthermore, little individual difference was observed in the results of the perceptual experiment. To the best of our knowledge, this study is the first in reporting the feasibility of indirect laser radiation for mid-air tactile rendering.


Subject(s)
Computer Simulation , Lasers , Physical Stimulation/methods , Touch Perception/physiology , Adult , Female , Humans , Male , Young Adult
5.
Biomed Mater Eng ; 26 Suppl 1: S1001-8, 2015.
Article in English | MEDLINE | ID: mdl-26405854

ABSTRACT

Laser can precisely deliver quantitative energy to a desired region in a non-contact way. Since it can stimulate regions and minutely control parameters such as the intensity, duration and frequency of stimulus, laser is often used for the areas such as low power laser treatment and clinical physiology. This study proposes simulation using pulse diode laser with reliable output and identifies laser parameters that can present a variety of somesthesis. It is found that typically, as frequency and energy increase, the ratio of feeling senses increases, and dominant sense moves from the sense of heat through tactile sense to pain. This study will be baseline data for studies of the sense of heat, tactile sense and pain, contribute to studying neurophysiology sector and be applied to basic clinical research.


Subject(s)
Lasers, Semiconductor , Pain/etiology , Thermosensing , Touch , Adult , Equipment Design , Female , Hot Temperature , Humans , Lasers, Semiconductor/adverse effects , Male , Young Adult
6.
Biomed Mater Eng ; 26 Suppl 1: S1773-80, 2015.
Article in English | MEDLINE | ID: mdl-26405946

ABSTRACT

A spectrophotometer is the basic measuring equipment essential to most research activity fields requiring samples to be measured, such as physics, biotechnology and food engineering. This paper proposes a system that is able to detect sample concentration and color information by using LED and color sensor. Purity and wavelength information can be detected by CIE diagram, and the concentration can be estimated with purity information. This method is more economical and efficient than existing spectrophotometry, and can also be used by ordinary persons. This contribution is applicable to a number of fields because it can be used as a colorimeter to detect the wavelength and purity of samples.


Subject(s)
Color , Colorimetry/instrumentation , Lighting/instrumentation , Semiconductors , Spectrum Analysis/instrumentation , Equipment Design , Equipment Failure Analysis , Reproducibility of Results , Sensitivity and Specificity
7.
Technol Health Care ; 23 Suppl 2: S473-80, 2015.
Article in English | MEDLINE | ID: mdl-26410514

ABSTRACT

BACKGROUND: Evaluation of joint movements is essential to choose an appropriate rehabilitation protocol for a patient. OBJECTIVE: The aim of this study is to suggest an alternative optical technique for measurement of joint angle which is convenient, inexpensive, and can be operated in real time. METHODS: According to the principle of the triangulation method, position sensitive detector (PSD) converts reflected light signals into distance-related voltages. Various parameters were investigated to increase detection range and resolution of joint angle measurements. RESULTS: The accuracy of the suggested optical sensor was verified by comparing with a commercial goniometer and 3D motion capture system. CONCLUSIONS: This method can be applied to monitor recovery progress for the patient in rehabilitation and sport science.


Subject(s)
Infrared Rays , Physical Therapy Modalities , Range of Motion, Articular , Signal Processing, Computer-Assisted , Biomechanical Phenomena , Humans , Movement
8.
Technol Health Care ; 23 Suppl 2: S511-7, 2015.
Article in English | MEDLINE | ID: mdl-26410518

ABSTRACT

BACKGROUND: The evaluation and control of lighting is crucial in physiological, biomedical, and industrial fields. Many kinds of lighting techniques based on LED have been developed due to its advantages. OBJECTIVE: The aim of this study is to develop the multi-colored LED system for healing purposes. METHODS: Light source with three-color chip LEDs was investigated to detect the dominant wavelength. RESULTS: The results show that the additive principle by three-color LEDs can be successfully applied to lighting system by generating a variety of colors. CONCLUSIONS: The results are expected to be useful in the field of light therapy and medicine. Applications of the developed light system are lighting therapies such as stimulating blood circulation and digestive processes, and controlling inflammation.


Subject(s)
Color , Lighting/instrumentation , Phototherapy/methods , Humans
9.
Technol Health Care ; 23 Suppl 2: S535-41, 2015.
Article in English | MEDLINE | ID: mdl-26410521

ABSTRACT

BACKGROUND: As the most abundant protein in human tissues, the use of collagen is essential in the fields of biological science and medicine. OBJECTIVE: The aim of this study is to investigate the mechanical effect of pulsed laser irradiation on collagen tissue. METHODS: With various laser parameters such as peak power, pulse width, and repetition rate, the induced stresses on samples were measured and analyzed. Monte Carlo simulation was performed to investigate the effect of laser parameters on the collagen sample. RESULTS: The results indicated that the magnitude of mechanical stress could be controlled by various laser parameters. CONCLUSIONS: This study can be used in biostimulation for therapy and mechanoreceptor stimulation for tactile application.


Subject(s)
Collagen Type I/radiation effects , Lasers, Semiconductor , Low-Level Light Therapy/methods , Stress, Mechanical , Animals , Fishes , Monte Carlo Method
10.
Biomed Mater Eng ; 24(1): 771-80, 2014.
Article in English | MEDLINE | ID: mdl-24211963

ABSTRACT

For diagnostic and therapeutic purposes, the joint angle measurement of a patient after an accident or a surgical operation is significant for monitoring and evaluating the recovering process. This paper proposed an optical fiber sensor for the measurement of angular displacement. The effect of beveled fiber angle on the detected light signal was investigated to find an appropriate mathematical model. Beveled fiber tips redirected the light over a range of angles away from the fiber axis. Inverse polynomial models were applied to directly obtain and display the joint angle change in real time with the Lab-VIEW program. The actual joint angle correlated well with the calculated LabVIEW output angle over the test range. The proposed optical sensor is simple, cost effective, small in size, and can evaluate the joint angle in real time. This method is expected to be useful in the field of rehabilitation and sport science.


Subject(s)
Fiber Optic Technology , Joints/physiology , Monitoring, Physiologic/instrumentation , Optical Fibers , Biomechanical Phenomena , Biomedical Engineering , Equipment Design , Humans , Light , Materials Testing , Models, Theoretical , Movement , Polymers , Postoperative Period , Software
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