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1.
Cureus ; 16(7): e64182, 2024 Jul.
Article in English | MEDLINE | ID: mdl-39119371

ABSTRACT

Metastatic melanoma presents a significant clinical challenge, characterized by its aggressive nature and propensity to spread to multiple organ systems. Despite advances in detection and treatment, managing metastatic disease remains complex. Here, we present the case of a 43-year-old male with metastatic melanoma displaying an unusual pattern of involvement, affecting the adrenal gland, liver, spleen, and bones. The diagnostic process was intricate, involving atypical hormonal profiles and a negative BRAF status, necessitating a comprehensive approach for accurate characterization and treatment selection. Immunotherapy demonstrated efficacy but also highlighted the emergence of immune-related adverse events, notably hyperglycemia. This case discusses the heterogeneous nature of metastatic melanoma and underscores the importance of a multidisciplinary approach, close monitoring, and consideration of evolving treatment strategies in its management.

2.
Cureus ; 15(1): e33299, 2023 Jan.
Article in English | MEDLINE | ID: mdl-36741651

ABSTRACT

Introduction Case reports form the base layer of the evidence pyramid, describing new or emerging diseases, side effects to treatments, common presentations of rare diseases, or rare presentations of common diseases. An important scholarly pursuit, writing case reports can be hindered by lack of time, training, and mentorship. Here, we describe a workshop incorporating case writing skills with mentorship opportunities to engage faculty and learners. Methods We designed and implemented a virtual, synchronous workshop addressing knowledge and attitudes on case reports for trainees and academic faculty at distributed sites. Participants discussed the contributions of case reports to the medical literature, key features of successful cases, approaches to writing learning objectives, and how to develop interesting cases into dynamic case reports. Case reports were discussed as a way to mentor learners to disseminate interesting cases as a source of clinical experience and academic productivity. A retrospective pre-post survey was collected two months after the workshop to evaluate its utility. Results Fifteen out of 42 participants responded to the survey. As a result of the workshop, respondents noted improvement in confidence in identifying and writing case reports and identifying and working with mentors or mentees, regardless of level of training or specialty. At the follow-up, seven (47%) respondents had identified a case and 10 (67%) had identified a mentor/mentee to write a case report with. Discussion This workshop, successfully delivered virtually, demonstrates the utility of a brief educational intervention in improving participant confidence in identifying and writing case reports with mentorship.

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