1.
Bioorg Med Chem Lett
; 21(13): 3890-3, 2011 Jul 01.
Article
in English
| MEDLINE
| ID: mdl-21641208
ABSTRACT
A simple and efficient synthetic approach toward a series of chiral aryl boronate esters, starting from D-xylose, as anti-microbial agents, is described herein. Minimum inhibitory concentration and zone of inhibition revealed that these derivatives exhibit potent anti-bacterial and anti-fungal properties. Herein, we report the first anti-microbial activity of this class of compounds. All products have been characterized by NMR ((1)H, (13)C and (11)B), IR, elemental and mass spectral study.