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Klin Khir ; (10): 77-9, 2015 Oct.
Article in Ukrainian | MEDLINE | ID: mdl-26946670

ABSTRACT

In experiment the impact of intraabdominal hypertension (IAH) on an acute pancreatitis (AP) course was studied up. The procedure of an acute experiment, using intraparenchymatose introduction of 40% solution of ethanol, was proposed. The isolated influence of IAH on target organs was investigated, as well as its impact on the simulated severe AP course. Morphological changes in pancreas, small intestine, kidneys, liver in an AP were studied up. While performing the investigation a negative impact of IAH in AP was noted, such as the polyorgan insufficiency occurence.


Subject(s)
Intra-Abdominal Hypertension/pathology , Multiple Organ Failure/pathology , Pancreatitis/pathology , Acute Disease , Animals , Animals, Outbred Strains , Disease Models, Animal , Ethanol , Histocytochemistry , Intestine, Small/pathology , Intra-Abdominal Hypertension/chemically induced , Kidney/pathology , Liver/pathology , Multiple Organ Failure/diagnosis , Pancreas/pathology , Pancreatitis/chemically induced , Pressure , Rats
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