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1.
In Vivo ; 37(4): 1901-1904, 2023.
Article in English | MEDLINE | ID: mdl-37369504

ABSTRACT

BACKGROUND/AIM: Cervicofacial actinomycosis is a rare entity. The manifestation of this disease in the context of osteomyelitis in the mandible is even rarer. CASE REPORT: This case report describes a 70-year-old female with a painful swelling in the left mandible. The swelling was initially noticed four weeks ago. Furthermore, the patient reported problems with medications concerning her type II diabetes mellitus. Due to multiple decayed teeth, the patient had multiple teeth extracted in recent years, including teeth 36-38 in the left mandible. Orthopantogram (OPG) and computed tomography (CT) scan showed an unspecific osteolysis in the left mandible. An incisional biopsy was performed revealing subacute necrotizing osteomyelitis of the mandible due to actinomyces. Furthermore, the patient was treated with open debridement, curettage, and decortication as well as long term antibiotics (amoxicillin + clavulanic acid) for 6 weeks. In addition, type II diabetes mellitus could be controlled with various medications (Metformin, Dapagliflozin). Clinical follow-up revealed no evidence of recurrence. CONCLUSION: Even though actinomycosis is rare, it should be included in the differential diagnosis of unspecific osteomyelitis of the jaw. Antibiotics and surgical decortication are the crucial therapy pillars when treating actinomycotic osteomyelitis in the mandible.


Subject(s)
Actinomycosis , Diabetes Mellitus, Type 2 , Osteomyelitis , Humans , Female , Aged , Diabetes Mellitus, Type 2/pathology , Actinomycosis/diagnosis , Actinomycosis/drug therapy , Anti-Bacterial Agents/therapeutic use , Mandible/pathology , Osteomyelitis/diagnosis , Osteomyelitis/drug therapy , Amoxicillin-Potassium Clavulanate Combination/therapeutic use
2.
Anticancer Res ; 43(4): 1869-1871, 2023 Apr.
Article in English | MEDLINE | ID: mdl-36974806

ABSTRACT

BACKGROUND: Tumors of the oral cavity must be differentiated into benign and malignant. Rare tumors must also be considered throughout the differential diagnosis when dealing with pathologic changes in the oral mucosa. Examples of rare benign tumors within the oral cavity are solitary fibrous tumors (SFTs). In recent years, individual case reports of SFTs in the oral cavity have been published showing a rising incidence of this rare entity. CASE REPORT: The present case report describes the occurrence of a subtype of SFT in the right buccal mucosa, the so-called giant cell angiofibroma (GCA). Histopathologically, GCA are distinguishable from SFT (NOS) by pseudovascular spaces lined by multinucleated giant cells. GCA generally shows a benign tumor behavior. The treatment of choice was surgical excision through an intraoral approach. CONCLUSION: To the best of our knowledge, this is one of a few reports of GCA arising in the buccal mucosa.


Subject(s)
Angiofibroma , Severe Fever with Thrombocytopenia Syndrome , Solitary Fibrous Tumors , Humans , Angiofibroma/surgery , Angiofibroma/diagnosis , Angiofibroma/pathology , Mouth Mucosa/surgery , Mouth Mucosa/pathology , Severe Fever with Thrombocytopenia Syndrome/pathology , Immunohistochemistry , Solitary Fibrous Tumors/pathology , Giant Cells/pathology
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