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1.
Catheter Cardiovasc Interv ; 91(4): 723-724, 2018 03 01.
Article in English | MEDLINE | ID: mdl-29532641

ABSTRACT

Real time radiation dose monitoring in the cath lab may provide immediate feedback for potential dose reduction during PCI. Radiation dose monitoring to predict potential tissue injury utilizes equipment measured air Kerma at the interventional reference point (IRP) with then calculated specific tissue peak skin dose. The role of the cath lab Quality Committee is not only to assess individual high dose radiation cases but also to create processes and assess new technologies to assure radiation dose is best utilized in all cases.


Subject(s)
Coronary Angiography , Radiation Dosage , Humans , Percutaneous Coronary Intervention , Radiation Monitoring , Skin , Treatment Outcome
2.
J Thorac Cardiovasc Surg ; 151(2): 402-8, 2016 Feb.
Article in English | MEDLINE | ID: mdl-26586360

ABSTRACT

OBJECTIVES: To determine whether nonselective preoperative carotid artery ultrasound screening alters management of patients scheduled for coronary artery bypass grafting (CABG), and whether such screening affects neurologic outcomes. METHODS: From March 2011 to September 2013, preoperative carotid artery ultrasound screening was performed on 1236 of 1382 patients (89%) scheduled to undergo CABG. Carotid artery stenosis (CAS) was classified as none or mild (any type 0%-59% stenosis), moderate (unilateral 60%-79% stenosis), or severe (bilateral 60%-79% stenosis or unilateral 80%-100% stenosis). RESULTS: A total of 1069 (86%) had

Subject(s)
Carotid Arteries/diagnostic imaging , Carotid Stenosis/diagnostic imaging , Coronary Artery Bypass , Coronary Artery Disease/surgery , Aged , Carotid Stenosis/complications , Carotid Stenosis/surgery , Coronary Artery Bypass/adverse effects , Coronary Artery Bypass/standards , Coronary Artery Bypass, Off-Pump , Coronary Artery Disease/complications , Coronary Artery Disease/diagnosis , Endarterectomy, Carotid , Female , Humans , Male , Middle Aged , Predictive Value of Tests , Prospective Studies , Quality Improvement , Quality Indicators, Health Care , Registries , Risk Factors , Severity of Illness Index , Stroke/etiology , Time Factors , Treatment Outcome , Ultrasonography
3.
Circ Arrhythm Electrophysiol ; 5(4): 640-9, 2012 Aug 01.
Article in English | MEDLINE | ID: mdl-22722658

ABSTRACT

BACKGROUND: Fibrotic and autonomic remodeling in heart failure (HF) increase vulnerability to atrial fibrillation (AF). Because AF electrograms (EGMs) are thought to reflect the underlying structural substrate, we sought to (1) determine the differences in AF EGMs in normal versus HF atria and (2) assess how fibrosis and nerve-rich fat contribute to AF EGM characteristics in HF. METHODS AND RESULTS: AF was induced in 20 normal dogs by vagal stimulation and in 21 HF dogs (subjected to 3 weeks of rapid ventricular pacing at 240 beats per minute). AF EGMs were analyzed for dominant frequency (DF), organization index, fractionation intervals (FIs), and Shannon entropy. In 8 HF dogs, AF EGM correlation with underlying fibrosis/fat/nerves was assessed. In HF compared with normal dogs, DF was lower and organization index/FI/Shannon entropy were greater. DF/FI were more heterogeneous in HF. Percentage fat was greater, and fibrosis and fat were more heterogeneously distributed in the posterior left atrium than in the left atrial appendage. DF/organization index correlated closely with %fibrosis. Heterogeneity of DF/FI correlated with the heterogeneity of fibrosis. Autonomic blockade caused a greater change in DF/FI/Shannon entropy in the posterior left atrium than left atrial appendage, with the decrease in Shannon entropy correlating with %fat. CONCLUSIONS: The amount and distribution of fibrosis in the HF atrium seems to contribute to slowing and increased organization of AF EGMs, whereas the nerve-rich fat in the HF posterior left atrium is positively correlated with AF EGM entropy. By allowing for improved detection of regions of dense fibrosis and high autonomic nerve density in the HF atrium, these findings may help enhance the precision and success of substrate-guided ablation for AF.


Subject(s)
Atrial Fibrillation/diagnosis , Atrial Function , Autonomic Nervous System/physiopathology , Electrophysiologic Techniques, Cardiac , Heart Failure/complications , Adipose Tissue/pathology , Adrenergic Antagonists/pharmacology , Animals , Atrial Appendage/innervation , Atrial Appendage/pathology , Atrial Fibrillation/etiology , Atrial Fibrillation/pathology , Atrial Fibrillation/physiopathology , Atrial Function/drug effects , Autonomic Denervation/methods , Autonomic Nervous System/drug effects , Cardiac Pacing, Artificial , Disease Models, Animal , Dogs , Fibrosis , Heart Atria/innervation , Heart Atria/pathology , Heart Failure/diagnosis , Heart Failure/pathology , Heart Failure/physiopathology , Muscarinic Antagonists/pharmacology , Predictive Value of Tests
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