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1.
J Laryngol Otol ; 135(2): 96-103, 2021 Feb.
Article in English | MEDLINE | ID: mdl-33568243

ABSTRACT

OBJECTIVE: This study aimed to provide a systematic review on survival outcome based on Pittsburgh T-staging for patients with primary external auditory canal squamous cell carcinoma. METHOD: This study was a systematic review in compliance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines performed until January 2018; pertinent studies were screened. Quality of evidence was assessed using the grading of recommendation, assessment, development and evaluation working group system. RESULTS: Eight articles were chosen that reported on 437 patients with external auditory carcinoma. The 5-year overall survival rate was 53.0 per cent. The pooled proportion of survivors at 5 years for T1 tumours was 88.4 per cent and for T2 tumours was 88.6 per cent. For the combined population of T1 and T2 cancer patients, it was 84.5 per cent. For T3 and T4 tumours, it was 53.3 per cent and 26.8 per cent, respectively, whereas for T3 and T4 tumours combined, it was 40.4 per cent. Individual analysis of 61 patients with presence of cervical nodes showed a poor survival rate. CONCLUSION: From this review, there was not any significant difference found in the survival outcome between T1 and T2 tumours. A practical classification incorporating nodal status that accurately stratifies patients was proposed.


Subject(s)
Carcinoma, Squamous Cell/mortality , Ear Canal/pathology , Head and Neck Neoplasms/mortality , Neoplasm Staging/methods , Aged , Carcinoma, Squamous Cell/classification , Carcinoma, Squamous Cell/complications , Carcinoma, Squamous Cell/therapy , Dura Mater/pathology , Ear Neoplasms/pathology , Facial Paralysis/epidemiology , Female , Head and Neck Neoplasms/secondary , Humans , Lymphatic Metastasis/pathology , Male , Middle Aged , Neoplasm Staging/statistics & numerical data , Parotid Gland/pathology , Parotid Gland/surgery , Retrospective Studies , Survival Rate
2.
J Laryngol Otol ; 132(6): 497-504, 2018 Jun.
Article in English | MEDLINE | ID: mdl-29888699

ABSTRACT

OBJECTIVE: To validate a newly introduced cartilage rim augmented temporalis fascia tympanoplasty technique by statistically comparing it with the morphological and audiological outcomes of traditional temporalis fascia tympanoplasty. METHODS: A retrospective comparative study was conducted on 115 patients who underwent tympanoplasty during 2013 and 2015. Fifty-eight patients underwent temporalis fascia tympanoplasty and 57 underwent cartilage rim augmented fascia tympanoplasty. RESULTS: In the cartilage fascia group, graft healing was achieved in 94.7 per cent of cases; in the temporalis fascia group, the graft take-up rate was 70 per cent. In those with a normal ossicular chain, the post-operative air-bone gap was within 20 dB in 92.6 per cent of cartilage fascia group cases and in 69.7 per cent of the temporalis fascia group cases, which was a statistically significant difference. Among the defective ossicular chain cases, the post-operative air-bone gap was within 20 dB in 76.9 per cent in the cartilage fascia group, as against 57.1 per cent in the temporalis fascia group. CONCLUSION: Cartilage rim augmented temporalis fascia tympanoplasty has a definite advantage over the temporalis fascia technique in terms of superior graft take up and statistically significant hearing gain in those with normal ossicular mobility.


Subject(s)
Ear Cartilage/transplantation , Fascia/transplantation , Myringoplasty/methods , Tympanic Membrane Perforation/surgery , Adolescent , Adult , Bone Conduction , Child , Ear Ossicles , Female , Hearing Loss, Conductive/complications , Humans , Male , Middle Aged , Retrospective Studies , Treatment Outcome , Tympanic Membrane Perforation/complications , Tympanoplasty/methods , Young Adult
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