Concentration and health risk assessment of per- and polyfluoroalkyl substances in cosmetic and personal care products.

Per and polyfluoroalkyl substances (PFAS) are toxicologically concerning because of their potential to bioaccumulate and their persistence in the environment and the human body. We determined PFAS levels in cosmetic and personal care products and assessed their health risks. We investigated the trends in concentrations and types of PFAS contaminants in cosmetic and personal care products before and after perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) were added to the list of persistent organic pollutants. The total PFAS concentration ranged from 1.98 to 706.75 ng g-1. The hazard quotients (HQs) for PFOA, PFOS and perfluorobutanesulfonic acid (PFBS) were lower than 1, indicating no appreciable risk to consumers. Assuming the simultaneous use of all product types and the worst-case scenario for calculations, perfluoroalkyl carboxylic acids and perfluoroalkane sulfonic acids (PFSAs) also had hazard indices lower than 1. We found that adverse effects are unlikely to occur when each type of cosmetic is used separately, or even when all product types are used together. Nevertheless, the persistence and bioaccumulation characteristics of additional PFAS present in cosmetics continue to be a cause for concern. Further research is necessary to investigate the long-term impacts of using such cosmetics and the associated risks to human health.

Analyzing temperature, humidity, and precipitation trends in six regions of Thailand using innovative trend analysis.

The change of temperature and weather parameters is a major concern affecting sustainable development and impacting various sectors, such as agriculture, tourism, and industry. Changing weather patterns and their impact on water resources are important climatic factors that society is facing. In Thailand, climatological features such as ambient temperature, relative humidity, and precipitation play a substantial role in affecting extreme weather events, which cause damage to the economy, agriculture, tourism, and livelihood of people. To investigate recent serious changes in annual trends of temperature, relative humidity, and precipitation in Thailand, this study used the Mann-Kendall (MK) test and innovative trend analysis (ITA) methods. The MK test showed that all six regions had an upward trend in temperature and humidity index (humidex, how hot the weather feels to the average person), while relative humidity and precipitation showed both upward and downward trends across different regions. The ITA method further confirmed the upward trend in temperature and humidex and showed that most data points fell above the 1:1 line. However, the upward trend in most variables was not significant at the 5% level. The southern and eastern regions showed a significant upward trend in relative humidity and humidex at a 5% level of significance according to the MK test. The output of this study can help in the understanding of weather variations and predict future situations and can be used for adaptation strategies.

Airborne microplastics: A narrative review of potential effects on the human respiratory system.

There has been growing evidence showing the widespread of airborne microplastics (AMPs) in many regions of the world, raising concerns about their impact on human health. This review aimed to consolidate recent literature on AMPs regarding their physical and chemical characteristics, deposition in the human respiratory tract, translocation, occurrence from human studies, and toxic effects determined in vitro and in vivo. The physical characteristics influence interactions with cell membranes, cellular internalization, accumulation, and cytotoxicity resulting from cell membrane damage and oxidative stress. In addition, prolonged exposure to AMP-associated toxic chemicals might lead to significant health effects. Most toxicological assessments of AMPs in vitro and in vivo have demonstrated that oxidative stress and inflammation are major mechanisms of action for their toxic effects. Elevated reactive oxygen species production could lead to mitochondrial dysfunction, inflammatory responses, and subsequent apoptosis in experimental models. To date, there has been some evidence suggesting exposure in humans. However, the data are still insufficient, and adverse human health effects need to be investigated. Future research on the existence, exposure, and health effects of AMPs is required for developing preventive and mitigation measures to protect human health.

Contamination and ecological risk of microplastics and phthalates in the surface water of the Tha Dee Sub-River basin, Nakhon Si Thammarat Province, Thailand.

Plastic waste has become a significant source of water pollution worldwide, releasing microplastics (MPs) and hazardous chemicals into aquatic environments. The purpose of this study was to determine the occurrence and ecological risk of MPs and phthalates (PAEs) in the surface water of the Tha Dee Sub-River basin in Nakhon Si Thammarat Province, Thailand. MPs, PAEs, and water quality parameters, including turbidity, pH, conductivity, dissolved oxygen, and salinity, were investigated simultaneously at 26 sampling stations. The average number of MPs per liter was 0.5 ± 0.4. Filaments were the most common MPs (59%), and transparent/white was the most prevalent color (51%). Four PAEs were found, with an average total concentration of 25.78 ± 93.87 µg/L, and diethyl phthalate was observed in the highest concentrations. Although there was no association between PAEs and other parameters, there was a significant correlation among particular PAEs (P < 0.05), indicating that they came from the same source. The pollution load index of MPs indicated a minor risk, but PAEs posed a medium risk to fish in the study area. This study's findings suggest that further research into the sources of PAEs and their contamination of aquatic life is needed.

Environmental sanitation and hygiene of elderly workers in Nakhon Si Thammarat Province, Thailand.

INTRODUCTION: Thailand will become a completely aged society in 2021 and a super-aged society in 2030, resulting in a high proportion of older people. Living environments, especially at home, play an essential health determinant for the elders. METHODS: This cross-sectional analytical study evaluated 319 households in Nakhon Si Thammarat Province according to the standard of housing sanitation for elders and assessed biological contamination in food, water, and indoor air in the homes. RESULTS: The housing assessment results revealed some issues that are necessary to be improved, i.e., the wet and dry areas in bathrooms were not separated (89.4%), there was no anti-slip sheet in the bathrooms (97.2%), and handrails were not suitably installed (96.2%). The proportion of coliform bacteria contamination in the samples of cooked rice, side dish, dish, spoon, elderly hand, and drinking water was 93.3, 83.9, 82.5, 88.1, 78.0 and 97.5%, respectively. The average total bacteria count in bedrooms and kitchens was 111 CFU/m3 and 149 CFU/m3, respectively. The average total fungi count was 83 CFU/m3 in bedrooms and 93 CFU/m3 in kitchens. Most indoor air quality parameters complied with the standards. CONCLUSIONS: Significant health risks for the elderly workers while living at home were injuries due to slipping fall in the house, especially in the bathroom, as well as foodborne and waterborne diseases. The health risks should be communicated to the elders. Prevention of the risks should be performed by the cooperation of relevant government agencies and the older adults in the study area.

Toluene and Heavy Metals in Small Automotive Refinishing Shops and Personal Protection of the Workers in Nakhon Si Thammarat, Thailand.

Chemical contamination and safe work practices of workers in automotive refinishing shops have been extensively studied in industrialized countries, but the evidence in developing countries is limited. This study aimed to evaluate chemical contamination and the use of personal protective equipment (PPE) of workers in local small-scale automotive refinishing shops in Nakhon Si Thammarat, Thailand. Airborne toluene and heavy metals, i.e., lead, chromium, and cadmium, were measured in 3 automotive refinishing shops. Toluene exposure assessed by urinary hippuric acid (n = 27) and metal contamination on workers' hands (n = 24) were also determined. Information on the use of PPE and personal hygiene practices of the workers was collected by questionnaires. Average ambient levels of toluene (0.04-18.26 ppm) and the metals (Pb: ND-26.34, Cr: 0.02-4.46, and Cd: ND-1.44 µg/m3) in all sites did not exceed the national standard levels of 200 ppm for toluene (1998) and 50, 12, and 5 µg/m3 for Pb, Cr, and Cd, respectively (2017). The mean ambient levels of these chemicals were highest in paint spray booths followed by nonpainting areas and office rooms, respectively. The highest level of urinary hippuric acid (1.13 g/g creatinine) was found in a painter but did not exceed the recommended biological exposure index of 1.6 g/g creatinine (2014). In contrast, the highest levels of lead and chromium detected on the workers' hands were found in body repair technicians. Direct hand contact without using gloves was suggested as a primary cause of metal contamination.

The Health Risks of Airborne Polycyclic Aromatic Hydrocarbons (PAHs): Upper North Thailand.

Every year, Northern Thailand faces haze pollution during the haze episode. The particulate matter (PM), including fine fraction (PM2.5), a coarse fraction (PM2.5-10), and 16 polycyclic aromatic hydrocarbons (PAHs), was measured in six provinces in upper north Thailand during the haze and non-haze episodes in 2018. Eighty-three percent of the PM2.5 measurements (21.8-194.0 µg/m3) during the haze episode exceeded the national ambient air quality standard in Thailand. All 16 PAHs were detected in the study area in both periods. The average concentration of total PAHs (particle-bound and gas-phase) during the haze episode was 134.7 ± 80.4 ng/m3, which was about 26 times higher than those in the non-haze (5.1 ± 9.7 µg/m3). Naphthalene and acenaphthene were the dominant PAHs in the gas phase; whereas, indeno[123-cd] pyrene, benzo[a]pyrene, and Benzo[ghi]Perylene were dominant in the particle-bound phase. The estimated inhalation excess cancer risk from PAHs exposure was 9.3 × 10-4 and 2.5 × 10-5 in the haze episode and non-haze, respectively. Diagnostic ratios and principal component analysis revealed that PAHs were derived from mixed sources of vehicle emission and solid combustion in the haze episode and vehicle emission in the non-haze period. High pollution levels of PM and large cancer risk attributable to the exposure of PAHs in the haze episode suggest urgent countermeasures to reduce the source emission, especially from the solid combustion in the area.