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Int Dent J ; 55(2): 61-6, 2005 Apr.
Article in English | MEDLINE | ID: mdl-15880959

ABSTRACT

Porphyria is a diverse group of diseases in which the biosynthesis of heme is disrupted by either genetic defects or environmental factors. This review gives an overview of the different types of porphyria and describes possible causes, clinical signs, diagnosis and therapy. In addition, the oral manifestations of porphyria and the potential implications of the disease for dental management are discussed.


Subject(s)
Mouth Diseases/etiology , Porphyria, Erythropoietic/complications , Porphyrias, Hepatic/complications , Algorithms , Anesthesia, Dental , Arginine/therapeutic use , Blister/drug therapy , Blister/etiology , Carbohydrates/therapeutic use , Contraindications , Heme/biosynthesis , Heme/therapeutic use , Humans , Mouth Diseases/drug therapy , Photophobia/etiology , Porphobilinogen Synthase/deficiency , Porphyria, Erythropoietic/diet therapy , Porphyria, Erythropoietic/drug therapy , Porphyrias, Hepatic/diet therapy , Porphyrias, Hepatic/drug therapy , Tooth Discoloration/etiology
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