Subject(s)
Antipsychotic Agents , Citalopram , Drug Therapy, Combination , Quetiapine Fumarate , Urinary Retention , Humans , Quetiapine Fumarate/adverse effects , Quetiapine Fumarate/administration & dosage , Urinary Retention/chemically induced , Citalopram/adverse effects , Citalopram/administration & dosage , Antipsychotic Agents/adverse effects , Antipsychotic Agents/administration & dosage , Male , Adult , Female , Selective Serotonin Reuptake Inhibitors/adverse effects , Selective Serotonin Reuptake Inhibitors/administration & dosageABSTRACT
Suicide is an important cause of death among patients affected by schizophrenia. The lifetime prevalence is 10-15%. The identification of factors associated with suicide attempts will help to identify preventive and therapeutic strategies to reduce the toll of suicide. Aims: The purpose of this study is to investigate the prevalence of suicide attempts and their sociodemographic and clinical characteristics in Moroccan patients with schizophrenia. Materials and methods: This is a cross-sectional study of patients admitted to our Hospital of Psychiatry in Morocco, between year and year, with adiagnosis f schizophrenia. Results: In our sample (n=304), 65 (21.4%) had attempted suicide. Suicide attempts were significantly and positively associated with a family history of bipolar disorder, comorbidity with a substance use disorder, a relatively short duration of treatment, poor adherence to medication, and severe general, positive, and depressive symptoms. Conclusion: The prevention of suicide risk requires the effective management of depressive and addictive comorbidities, the reduction of schizophrenia symptoms through appropriate treatment and an effort to improve adherence.
