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Emerg Infect Dis ; 26(8): 1839-1841, 2020 Aug.
Article in English | MEDLINE | ID: mdl-32384045

ABSTRACT

To evaluate lymphopenia as a marker for coronavirus disease severity, we conducted a meta-analysis of 10 studies. Severe illness was associated with lower lymphocyte and higher leukocyte counts. Using these markers for early identification of patients with severe disease may help healthcare providers prioritize the need to obtain therapy.


Subject(s)
Betacoronavirus/pathogenicity , Coronavirus Infections/diagnosis , Coronavirus Infections/epidemiology , Leukocytosis/diagnosis , Lymphopenia/diagnosis , Pandemics , Pneumonia, Viral/diagnosis , Pneumonia, Viral/epidemiology , Biomarkers/analysis , COVID-19 , Comorbidity , Coronavirus Infections/pathology , Coronavirus Infections/virology , Hospitalization , Humans , Leukocyte Count , Leukocytosis/epidemiology , Leukocytosis/pathology , Leukocytosis/virology , Lymphopenia/epidemiology , Lymphopenia/pathology , Lymphopenia/virology , Pneumonia, Viral/pathology , Pneumonia, Viral/virology , Predictive Value of Tests , SARS-CoV-2 , Severity of Illness Index
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