Unexpected Previously Unknown Diversity of the Genus Microphor Macquart (Diptera: Dolichopodidae: Microphorinae) in the West Palaearctic.

Microphor baechlii sp. nov. (Switzerland, Turkey), M. chvalai sp. nov. (France), M. nevadensis sp. nov. (Spain), M. pallipes sp. nov. (Italy), and M. turcicus sp. nov. (Turkey) are described and illustrated. The neotype of M. anomalus (Meigen, 1824) is designated. Males of all known Palaearctic species of Microphor are keyed, genitalia are illustrated for new species and species previously inadequately illustrated, and main diagnostic characters are discussed. Microphorstrobli Chvála, 1986 is newly recorded from Bulgaria, M. anomalus (Meigen, 1824) is newly recorded from Turkey, and M. holosericeus (Meigen, 1804) is newly recorded from Turkey and Portugal.

Electric field detection as floral cue in hoverfly pollination.

Pollinators can detect the color, shape, scent, and even temperature of the flowers they want to visit. Here, we present the previously unappreciated capacity of hoverflies (Eristalis tenax and Cheilosia albipila) to detect the electric field surrounding flowers. Using hoverflies as key dipteran pollinators, we explored the electrical interactions between flies and flowers-how a hoverfly acquired a charge and how their electrical sensing ability for target flowers contributed to nectar identification and pollination. This study revealed that rapid variations in a floral electric field were related to a nectar reward and increased the likelihood of the fly's return visits. We found that thoracic hairs played a role in the polarity of hoverfly charge, revealing their electro-mechanosensory capability, as in bumblebees (Bombus terrestris). Electrophysiological analysis of the hoverfly's antennae did not reveal neural sensitivity to the electric field, which favors the mechanosensory hairs as putative electroreceptive organs in both species of hoverflies.

Fanniidae (Diptera): new species, new records and first description of the male of Fannia latifrontalis Hennig.

Fannia bohemica sp. nov. (Czech Republic, Slovakia) is described and illustrated. Male of F. latifrontalis Hennig, 1955 is described and illustrated for the first time. Fannia jezoensis Nishida, 1976 is first reported from West Palaearctic, Fannia morrisoni Malloch, 1913 is first recorded from Palaearctic Region. Fannia umbrosa (Stein, 1895) and F. armata (Meigen, 1826; first record based on morphologically identified specimens) are new records from Nearctic Region. Six species (Fannia fuscitibia Stein, 1920, F. latifrontalis, F. limbata (Tiensuu, 1938), F. verrallii (Meade, 1891), F. gotlandica Ringdahl, 1926 and F. spathiophora, Malloch, 1918) are recorded for the first time from Slovakia.

Four new West Palaearctic species and new distributional records of Hybotidae (Diptera).

Megagrapha starki Barták & Grootaert, sp. nov. (Poland, Russia, Slovakia), Oedalea portugalica Barták & Grootaert, sp. nov. (Portugal), Hybos conicus Grootaert & Barták, sp. nov. (Greece, Turkey), and Platypalpus obscuroides Barták & Grootaert, sp. nov. (Slovakia) are described and illustrated. Diagnostic characters are discussed. The female of Syndyas merzi Shamshev & Grootaert, 2012 is described for the first time. New distributional records are presented: Megagrapha europaea Papp & Földvári, 2001 is first reported from Slovakia and Syndyas merzi Shamshev & Grootaert, 2012 is first reported from Turkey.

Plasticity-Related Activity in the Hippocampus, Anterior Cingulate, Orbitofrontal, and Prefrontal Cortex Following a Repeated Treatment with D2/D3 Agonist Quinpirole.

Quinpirole (QNP) sensitization is a well-established model of stereotypical checking relevant to obsessive-compulsive disorder. Previously, we found that QNP-treated rats display deficits in hippocampus-dependent tasks. The present study explores the expression of immediate early genes (IEG) during QNP-induced stereotypical checking in the hippocampus, anterior cingulate cortex (ACC), orbitofrontal cortex (OFC), and medial prefrontal cortex (mPFC). Adult male rats were injected with QNP (0.5 mg/mL/kg; n = 15) or saline (n = 14) daily for 10 days and exposed to an arena enriched with two objects. Visits to the objects and the corners of the arena were recorded. QNP-treated rats developed an idiosyncratic pattern of visits that persisted across experimental days. On day 11, rats were exposed to the arena twice for 5 min and sacrificed. The expression of IEGs Arc and Homer1a was determined using cellular compartment analysis of temporal activity by fluorescence in situ hybridization. IEG-positive nuclei were counted in the CA1 area of the hippocampus, ACC, OFC, and mPFC. We found significantly fewer IEG-positive nuclei in the CA1 in QNP-treated rats compared to controls. The overlap between IEG expressing neurons was comparable between the groups. We did not observe significant differences in IEG expression between QNP treated and control rats in ACC, OFC, and mPFC. In conclusion, treatment of rats with quinpirole decreases plasticity-related activity in the hippocampus during stereotypical checking.

Two new West Palaearctic species of Atelestus Walker (Diptera, Atelestidae) and new distributional records of the family.

Atelestus turcicus Barták, sp. nov. (Turkey) and Atelestus ibericus Barták, sp. nov. (Spain) are described and illustrated. A key to all known Palaearctic species of Atelestus is provided and the main diagnostic characters are discussed. The female of Nemedina acutiformis Carles-Tolrá, 2008 is described for the first time. New distributional records are presented: Atelestus dissonans Collin, 1961 - first records from Spain and Bulgaria, A. pulicarius (Fallén, 1816) - first record from Turkey, Nemedina alamirabilis Chandler, 1981 - first record from Bulgaria and N. acutiformis Carles-Tolrá, 2008 - first record from Turkey.

Risk element accumulation in Coleoptera and Hymenoptera (Formicidae) living in an extremely contaminated area-a preliminary study.

The risk element accumulation ability of two groups of epigeic species, insects from families Coleoptera and Hymenoptera (namely Formicidae), was determined and related to soil risk element content and bioaccessibility. The study was conducted in the district of Príbram, Czech Republic, which was characterised by extremely high aged pollution in the soils, including risk elements, especially As, Pb, Zn and Cd, due to the former mining and smelting activity. Four sampling sites differing in their pseudo-total risk element contents were selected and composite samples of individuals representing either Coleoptera or Formicidae were sampled at the individual sampling points. The results indicate the ability of Coleoptera and Formicidae organisms to accumulate risk elements, especially at the location with extremely high soil risk element content. In soil containing up to 841 mg As kg-1, 84.6 mg Cd kg-1, 4250 mg Pb kg-1 and 8542 mg Zn kg-1, contents in insect bodies reached 239 mg As kg-1 As, 24.2 mg Cd kg-1, 70.4 mg Pb kg-1 and 335 mg Zn kg-1 in beetles and up to 20.9 mg As kg-1, 29.9 mg Cd kg-1, 111 mg Pb kg-1 and 657 mg Zn kg-1 in ants. Therefore, bioaccumulation factors (BAFs) varied between 0.02 and 0.55. Increasing Cd content in Coleoptera bodies with increasing soil pseudo-total element content was observed only among the investigated elements. However, the results indicate increasing BAF values with decreasing soil element levels, especially for Cd, Pb and Zn, indicating limited uptake of elements by the organisms living in contact with extremely contaminated soil.

Neural and neuronal discoordination in schizophrenia: From ensembles through networks to symptoms.

Despite the substantial knowledge accumulated by past research, the exact mechanisms of the pathogenesis of schizophrenia and causal treatments still remain unclear. Deficits of cognition and information processing in schizophrenia are today often viewed as the primary and core symptoms of this devastating disorder. These deficits likely result from disruptions in the coordination of neuronal and neural activity. The aim of this review is to bring together convergent evidence of discoordinated brain circuits in schizophrenia at multiple levels of resolution, ranging from principal cells and interneurons, neuronal ensembles and local circuits, to large-scale brain networks. We show how these aberrations could underlie deficits in cognitive control and other higher order cognitive-behavioural functions. Converging evidence from both animal models and patients with schizophrenia is presented in an effort to gain insight into common features of deficits in the brain information processing in this disorder, marked by disruption of several neurotransmitter and signalling systems and severe behavioural outcomes.

Orexin supplementation in narcolepsy treatment: A review.

Narcolepsy is a rare, chronic neurological disease characterized by excessive daytime sleepiness, cataplexy, vivid hallucinations, and sleep paralysis. Narcolepsy occurs in approximately 1 of 3000 people, affecting mainly adolescents aged 15 to 30 years. Recently, people with narcolepsy were shown to exhibit extensive orexin/hypocretin neuronal loss. The orexin system regulates sleep/wake control via complex interactions with monoaminergic, cholinergic and GABA-ergic neuronal systems. Currently, no cure for narcolepsy exists, but some symptoms can be controlled with medication (eg, stimulants, antidepressants, etc). Orexin supplementation represents a more sophisticated way to treat narcolepsy because it addresses the underlying cause of the disease and not just the symptoms. Research on orexin supplementation in the treatment of sleep disorders has strongly increased over the past two decades. This review focuses on a brief description of narcolepsy, the mechanisms by which the orexin system regulates sleep/wake cycles, and finally, possible therapeutic options based on orexin supplementation in animal models and patients with narcolepsy.

Empidinae (Diptera, Empididae) from Bulgaria with new records and descriptions of three new species.

Empis (Leptempis) rhodopensis Barták sp. n., Hilarabulgarica Barták sp. n., and Rhamphomyia (Amydroneura) stojanovae Barták sp. n. are described from Bulgaria. Altogether 32 species of Empididae are first reported from Bulgaria.

Hybotidae (Diptera) from Turkey, with descriptions of seven new species.

The family Hybotidae is systematically studied from Turkey for the first time. Altogether 51 species are reported from Turkey, of which 36 species are first recorded from this country and seven species are described as new for science: Platypalpus academicus sp. nov., P. anomalus sp. nov., P. bohousi sp. nov., P. diminuticornis sp. nov., P. dursuni sp. nov., P. moceki sp. nov., and P. seticauda sp. nov. Seven additional probably undescribed species remain unnamed due to insufficient material. Tachypeza subnubila Raffone, 2002 is proposed as new subjective junior synonym of Tachypeza nubila (Meigen, 1804).

Checklist of flesh flies of Turkey (Diptera, Sarcophagidae).

A checklist of 153 flesh fly species (Diptera, Sarcophagidae) recorded to date from Turkey is presented. Updating the list was necessary due to the numerous recent records. Records are listed according to provinces.

A new species of Gaurax from the Czech Republic (Diptera, Chloropidae).

Gauraxsiostrzoneki sp. n. (Diptera, Chloropidae) is described from the Czech Republic and the main differential characters are illustrated. A key to the European species of the genus is provided.

New records of Sarcophagidae from Turkey (Diptera).

Faunistic records of 68 flesh fly species are presented, and altogether, 22 species are recorded from Turkey for the first time. A further 46 species were recorded for the first time in at least one Turkish province. This paper presents the first locality data for four additional species, which were previously mentioned only generically in catalogues. One new synonym has been established, Servaisia (s. str.) rybaltschenkoi (Verves, 1977) = Blaesoxipha ataturkia Lehrer, 2008, syn. n. Two new combinations are proposed: Helicophagella (Parabellieria) dreyfusi (Lehrer, 1994), comb. n. and Helicophagella (s. str.) bellae (Lehrer, 2000), comb. n.

Frit flies of Turkey with descriptions of two new species and new records (Diptera, Chloropidae).

Faunistic records for 88 frit flies species from southwestern Turkey (Mugla province) and from Samsun (north Turkey) are given. Two species, Dicraeus civelekisp. n., and Meromyza samsunensissp. n., are described as new to science. Altogether, nine genera (Calamoncosis, Eribolus, Gaurax, Incertella, Speccafrons, Trachysiphonella, Chloropsina, Eutropha, and Lagaroceras) and 46 species are recorded for the first time from Turkey.

Acute systemic MK-801 induced functional uncoupling between hippocampal areas CA3 and CA1 with distant effect in the retrosplenial cortex.

The hippocampus and retrosplenial cortex are integrated within a higher-order cognitive circuit supporting relational (spatial, contextual, episodic) forms of learning and memory. Hippocampal place cells can coordinate multiple parallel representations in the same physical environment. Novel environment exploration triggers expression of immediate-early genes (IEGs) Arc and Homer1a in spatial context-specific ensembles of CA1 and CA3 neurons. Less is know about ensemble coding in the retrosplenial cortex (RSC), a region directly connected and functionally coupled to CA1. Hippocampal and retrosplenial damage is found in patients with schizophrenia alongside cognitive deficits affecting relational memory. Systemic administration of non-competitive NMDAR antagonists such as MK-801 is used to model psychosis in animals and humans. Acute systemic MK-801 (0.15 mg/kg) impaired cognitive control in rats and ensemble code for spatial context in CA1. Here, we use expression of immediate-early genes Arc and Homer 1a to examine ensemble coding in rat CA3 and RSC to test if the effect of MK-801 extends upstream and downstream of CA1, respectively. Different rats explored the same context twice (A/A), explored two distinct contexts (A/B) or remained in their home cage (CC). In contrast to CA1, MK-801 did not affect ensemble coding in CA3. Unlike CA3 and CA1, similarity of RSC ensembles active during exploration did not reflect change in spatial context, but MK-801 (0.15 mg/kg) increased similarity in RSC ensembles active during spontaneous behavior in the home cage. The data provide support for MK-801-induced functional uncoupling between CA3 and CA1 and suggest that ensemble coding deficit may extend downstream of CA1. This deficit may reflect hyperassociative state in the cognitive circuit underlying cognitive disorganization in psychosis. © 2016 Wiley Periodicals, Inc.

New species and new synonyms in European Platypalpus (Diptera: Hybotidae).

Platypalpus mosticensis sp. nov. (Czech Republic) and P. ibericus sp. nov. (Portugal) are described and illustrated. The male of Platypalpus silvahumidus Barták & Kubík, 2015 is described and illustrated for the first time. Types of all species of Platypalpus described by Italian entomologist Gianni Raffone between 2002 and 2010 were studied. The following nine new synonyms are proposed: Platypalpus canzonerii Raffone, 2002 = P. maculimanus (Zetterstedt, 1842); Platypalpus litoreus Raffone, 2010 = P. flavicornis (Meigen, 1822); Platypalpus pseudoalter Raffone, 2003 = P. boreoalpinus Frey, 1943; Platypalpus pseudostroblii Raffone, 2002 = P. exilis (Meigen, 1822); Platypalpus subwagneri Raffone, 2003 = P. exilis (Meigen, 1822); Platypalpus romaniolus Raffone, 2010 = P. longiseta (Zetterstedt, 1842); Platypalpus subarticulatus Raffone, 2002 = P. articulatus Macquart, 1827; Platypalpus submaculus Raffone, 2002 = P. macula (Zetterstedt, 1842); Platypalpus subpectoralis Raffone, 2002 = P. pectoralis (Fallén, 1815). Variability in the male genitalia of P. boreoalpinus is discussed.

Fanniidae (Diptera): new synonym, new records and an updated key to males of European species of Fannia.

Based on revision of large recent collections of the authors, the following five species are first recorded from the Czech Republic: Fannia collini d'Assis-Fonseca, 1966 (simultaneously first record in Central Europe), Fannia lugubrina (Zetterstedt, 1838), Fannia melania (Dufour, 1839), Fannia slovaca Gregor & Rozkosný, 2005, and Fannia brinae Albuquerque, 1951 (simultaneously first record from low altitudes). Another species, Fannia alpina Pont, 1970, is first recorded from Slovak Republic, and Fannia cothurnata (Loew, 1873) is first recorded from Kazakhstan. An updated key to males of European species of Fannia is presented. A list of Czech and Slovak Fanniidae is appended. One new synonym is established: Fannia lucida Chillcott, 1961 is considered junior synonym of Fannia norvegica Ringdahl, 1934. Altogether two species are first recorded from Bohemia [Fannia cothurnata (Loew, 1873) and Fannia vespertilionis Ringdahl, 1934] and three for Moravia [Fannia alpina Pont, 1970, Fannia conspecta Rudzinski, 2003, and Fannia limbata (Tiensuu, 1938) - this species considered in Central Europe very rare was found in numbers near waters both running and standing in early spring under unusually warm temperature conditions].

Three new species of Tricimba Lioy from the West Palaearctic region (Diptera, Chloropidae).

Tricimba rudolfi Kubík, sp. n. (Czech Republic, Portugal), Tricimba chalupi Kubík, sp. n. (Czech Republic), and Tricimba dursuni Kubík, sp. n. (Turkey) are described and illustrated. First records of Tricimba kaplanae Dely-Draskovits, 1983 from Corsica and Tricimba hungarica Dely-Draskovits, 1983 from Turkey are listed.

Palaearctic species of Rhamphomyia (Pararhamphomyia) anfractuosa group (Diptera, Empididae).

Palaearctic species of the Rhamphomyia (Pararhamphomyia) anfractuosa group are revised. Rhamphomyia (Pararhamphomyia) biflexatasp. n., Rhamphomyia (Pararhamphomyia) lineodorsatasp. n., Rhamphomyia (Pararhamphomyia) nudiscutellatasp. n., and Rhamphomyia (Pararhamphomyia) shatalkinisp. n. (all from Russian Far East) are described and illustrated. A key to Palaearctic species of the Rhamphomyia (Pararhamphomyia) anfractuosa group is provided.