1.
Org Lett
; 21(21): 8509-8513, 2019 Nov 01.
Article
in English
| MEDLINE
| ID: mdl-31625755
ABSTRACT
Friedel-Crafts-type acylation of alkenes with acyl chlorides has been successfully conducted with a wide substrate scope by the combined use of AlCl3 and 2,6-dibromopyridine. Trisubstituted alkenes afford allylketones or vinylketones depending on the presence or absence of hydrogen atom(s) at the ß-position to the acylation site, while monosubstituted alkenes exclusively afford vinylketones.