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Khirurgiia (Mosk) ; (6): 44-50, 2015.
Article in Russian | MEDLINE | ID: mdl-26271423

ABSTRACT

It was analyzed the medical records of 231 patients who underwent living kindred donor kidney transplantation. Early postoperative complications were observed in 51 (22%) patients including infectious events in 30 cases namely pyelonephritis (13), pneumonia (6), sepsis (5), wound infection (3), pulmonary tuberculosis (2) and esophageal mycosis (1). Microflora investigation revealed predominantly gram-negative bacteria including enterobacteriaceae (K. pneumoniae, E. coli and E. cloacae) and nonfermentable bacteria (P. aeruginosa, Acinetobacter spp.). Analysis of 7-year antibiotic susceptibility showed that polymyxin, imipenem, cefoperazone/sulbactam and amikacin preserve their activity against enterobacteriaceae and pseudomonas; linezolid, vancomycinum and moxifloxacin--against staphylococcus; voriconazole, amphotericinum B and fluconazole--against Candida spp. These medicines are preferred for antibiotic prevention of perioperative and early postoperative infectious complications.


Subject(s)
Antibiotic Prophylaxis/methods , Kidney Transplantation/methods , Surgical Wound Infection/epidemiology , Adolescent , Adult , Allografts , Child , Child, Preschool , Female , Humans , Incidence , Infant , Living Donors , Male , Middle Aged , Retrospective Studies , Russia/epidemiology , Surgical Wound Infection/prevention & control , Young Adult
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