[Microelements balance and correction in athletes++ under high muscular load]. / Balans mikro'elementov i ego korrektsiya u sportsmenov pod vozdelstvieem bol'shol myshechnol nagruzki.

The balance studies among the high-qualified adult sportsmen during the winter period of practices had shown that of the day of a 30-km cross the contents of iron, copper and manganese in the food ration fell to the lowest level of the physiological standard of people not going into sports due to sufficient physical load the process of microcomponents' secretion through bowels and kidneys was outstripping their replenishment from food. The balance of all three microcomponents was negative. During the following three days after the cross due to disbalanced food ration caused by the content of microcomponents the losses of iron and copper were not compensated. The enrichment of the food rations by the set of components caused the hold-up of iron, copper and manganese in sportsmen bodies. The increased usage of the medical iron resulted in sufficient growth of copper and manganese excretion through alimentary canal.

[Catecholamine levels in rats during cooling and administration of succinic acid derivatives]. / Soderzhanie katekholaminov v organizme krys pri okhlazhdenii na fone proizvodnykh iantarnoi kisloty.

The effect of tonibral and another succinate derivative (IOH-13) on catecholamine level in the rat organs was studied after 48 hours of acute exposure to low temperature (-15 degrees C). The injection of these drugs prevented the decrease in catecholamine concentration in the heart and stabilized its content in the muscles. The higher survival of rats injected IOH-13, as compared to those injected tonibral, correlated with the higher catecholamine level in the heart muscle. It is suggested that adaptive increase of biogenic amines in the heart muscle plays an important role in the protective effect of these drugs during severe cooling.

[Effect of sodium succinate on metabolic and morphological changes in acute cooling]. / Vliianie suktsinata natriia na metabolicheskie i morfologicheskie izmeneniia pri ostrom okhlazhdenii.

The effect of sodium succinate preinjection (16 mg/kg) on the resistance of mice to acute low-temperature exposure was studied. The measurements were taken of the changes in blood glucose concentration, of the content in the heart of macroergic compounds and glycogen, and of succinate dehydrogenase activity. Cardiomyocytes were studied by electron microscopy. The data indicate that greater preservation of macroergic compounds and stabilization of the ultrastructure of myocardial mitochondria play a role in the mechanism by which the animals' resistance to intense cooling is increased after sodium succinate injection.