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1.
Rev Esp Quimioter ; 37(3): 257-265, 2024 06.
Article in Spanish | MEDLINE | ID: mdl-38520173

ABSTRACT

OBJECTIVE: To analyse a new risk score to predict bacteremia (MPB-INFURG-SEMES) in the patients with solid tumor attender for infection in the emergency departments (ED). METHODS: Prospective, multicenter observational cohort study of blood cultures (BC) obtained from adult patients with solid neoplasia treated in 63 EDs for infection from November 1, 2019, to March 31, 2020. The predictive ability of the model was analyzed with the area under the Receiver Operating Characteristic curve (AUC-ROC). The prognostic performance for true bacteremia was calculated with the chosen cut-off for getting the sensitivity, specificity, positive predictive value and negative predictive value. RESULTS: A total of 857 blood samples wered cultured. True cases of bacteremia were confirmed in 196 (22.9%). The remaining 661 cultures (77.1%) wered negative. And, 42 (4.9%) were judged to be contaminated. The model's area under the receiver operating characteristic curve was 0.923 (95% CI,0.896-0.950). The prognostic performance with a model's cut-off value of ≥ 5 points achieved 95.74% (95% CI, 94,92-96.56) sensitivity, 76.06% (95% CI, 75.24-76.88) specificity, 53.42%(95% CI, 52.60-54.24) positive predictive value and 98.48% (95% CI, 97.66- 99.30) negative predictive value. CONCLUSIONS: The MPB-INFURG-SEMES score is useful for predicting bacteremia in the adults patients with solid tumor seen in the ED.


Subject(s)
Bacteremia , Emergency Service, Hospital , Neoplasms , Humans , Bacteremia/microbiology , Bacteremia/drug therapy , Neoplasms/complications , Prospective Studies , Female , Male , Middle Aged , Aged , ROC Curve , Prognosis , Adult , Sensitivity and Specificity , Blood Culture , Predictive Value of Tests , Risk Assessment , Cohort Studies
3.
Rev. esp. patol. torac ; 31(4): 259-261, dic. 2019. ilus
Article in Spanish | IBECS | ID: ibc-187186

ABSTRACT

La aspiración de cuerpos extraños en las vías aéreas puede ser potencialmente mortal. Estos fenómenos ocurren sobre todo en niños, siendo la primera causa de muerte accidental en menores de un año. No obstante, que esto ocurra en pacientes adultos es menos frecuente. La clínica suele ser muy variable, pudiendo persistir la sensación de ahogo y disnea tras la aspiración del cuerpo extraño o bien una vez concluida la aspiración, encontrarse asintomático. Una buena anamnesis es primordial para orientar el diagnóstico y desobstruir la vía aérea lo más pronto posible. El tratamiento de elección en pacientes adultos es el broncoscopio flexible, también llamado fibrobroncoscopio. A continuación, describimos un caso de un paciente de 44 años que acude a Urgencias por presentar accidentalmente una aspiración de un destornillador dental. Aunque se encontraba asintomático al momento de la valoración, las características de dicho cuerpo extraño (tamaño, punzante, localización, etc.) hicieron necesaria una derivación a un centro de referencia y una broncoscopia de urgencia


The aspiration of foreign matter into the airways can be potentially fatal. This phenomenon occurs primarily in children, constituting the leading cause of death in children under one year old. However, its occurrence in adult patients is less frequent. Symptoms tend to vary greatly, from a persistent feeling of choking or dyspnea after the aspiration of the foreign matter to being asymptomatic after the aspiration. A thorough medical history is key to guide the diagnosis and clear the airway as soon as possible. The treatment of choice in adult patients is flexible bronchoscopy, also known as fibrobronchoscopy. Below, we will describe the case of a 44-year-old patient who went to the emergency room after accidentally aspirating a dental screwdriver. Although he was asymptomatic at the time of the examination, the characteristics of the foreign matter (size, sharpness, location, etc.) made referral to a reference center and an emergency bronchoscopy necessary


Subject(s)
Humans , Male , Adult , Foreign-Body Reaction/complications , Respiratory Aspiration/complications , Bronchoscopy/methods , Risk Factors , Radiography, Thoracic , Amoxicillin-Potassium Clavulanate Combination/administration & dosage
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