Subject(s)
Humans , Female , Aged , Ileum/pathology , Intestine, Small/pathology , Melanoma/pathology , Melanoma/surgery , Skin Neoplasms/pathology , Skin Neoplasms/surgeryABSTRACT
The vast majority of malignant melanomas in the small intestine are metastasis of cutaneous tumors. Few cases have been published on primary melanomas in this location, some authors consider that they are always metastatic and that the primary tumor has regressed. In this letter, we present the case of a 77-year-old woman with a history of cutaneous melanoma excision 38 years ago who was diagnosed with ileal melanoma in the absence of other lesions during the study of iron deficiency anemia, and we discuss about the origin of this type of neoplasms.
Subject(s)
Melanoma , Skin Neoplasms , Female , Humans , Aged , Melanoma/surgery , Melanoma/pathology , Skin Neoplasms/surgery , Skin Neoplasms/pathology , Intestine, Small/pathology , Ileum/pathologyABSTRACT
UNLABELLED: Pancreatic carcinoid tumours are extremely infrequent. Usually, the biological behaviour is indolent and diagnosis is late and often casual. We present the case of a patient initially diagnosed as having liver metastasis of unknown origin. PET identified a primary pancreatic site and the initial histologic diagnosis was adenocarcinoma. Following an uncertain response to chemo- and radio-therapy the repeat histologic assessment indicated a carcinoid tumour of the pancreas. After complete surgical resection and liver transplantation, patient remains free of disease. CONCLUSIONS: The co-existence of several diseases with similar morpho-structural features makes diagnosis complicated. PET is of uncertain use in the evaluation of carcinoid tumours, and is considered inferior to 111Indium-octreotide scan. The only curative treatment is surgical resection, with liver transplantation as a valid option in the treatment of these tumours.
Subject(s)
Carcinoid Tumor/diagnosis , Diagnostic Errors , Pancreatic Neoplasms/diagnosis , Adenocarcinoma/diagnosis , Adult , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Carcinoid Tumor/diagnostic imaging , Carcinoid Tumor/drug therapy , Carcinoid Tumor/radiotherapy , Carcinoid Tumor/secondary , Carcinoid Tumor/surgery , Cisplatin/administration & dosage , Combined Modality Therapy , Deoxycytidine/administration & dosage , Deoxycytidine/analogs & derivatives , Humans , Liver Neoplasms/diagnosis , Liver Neoplasms/secondary , Liver Neoplasms/surgery , Liver Transplantation , Male , Pancreatectomy , Pancreatic Neoplasms/diagnostic imaging , Pancreatic Neoplasms/drug therapy , Pancreatic Neoplasms/radiotherapy , Pancreatic Neoplasms/surgery , Positron-Emission Tomography , Remission Induction , GemcitabineABSTRACT
No disponible
Pancreatic carcinoid tumours are extremelyinfrequent. Usually, the biological behaviour isindolent and diagnosis is late and often casual. Wepresent the case of a patient initially diagnosed ashaving liver metastasis of unknown origin. PETidentified a primary pancreatic site and the initialhistologic diagnosis was adenocarcinoma.Following an uncertain response to chemo- andradio-therapy the repeat histologic assessmentindicated a carcinoid tumour of the pancreas. Aftercomplete surgical resection and livertransplantation, patient remains free of disease.Conclusions: The co-existence of several diseaseswith similar morpho-structural features makesdiagnosis complicated. PET is of uncertain use inthe evaluation of carcinoid tumours, and isconsidered inferior to 111Indium-octreotide scan.The only curative treatment is surgical resection,with liver transplantation as a valid option in thetreatment of these tumours
Subject(s)
Male , Adult , Humans , Carcinoid Tumor/pathology , Pancreatic Neoplasms/pathology , Liver Neoplasms/secondary , Neoplasm Metastasis/pathologyABSTRACT
In 10%-15% of patients, myasthenia gravis is associated with thymoma. Because of its site, this tumour can have an un-noticed clinical history over a considerable time and be diagnosed when adjacent structures such as mediastinal vessels, heart or trachea become infiltrated. We present a patient with thymoma and infiltration of the superior vena cava, and which represents an incipient vena cava syndrome. The surgical treatment consisted of complete resection of the tumour including partial replacement of the vena cava with a pericardial patch. The surgery was complemented with radiotherapy.
Subject(s)
Thymoma/surgery , Thymus Neoplasms/surgery , Vascular Neoplasms/surgery , Vena Cava, Superior , Aged , Humans , Male , Neoplasm Invasiveness , Surgical Procedures, Operative/methods , Thymoma/pathology , Thymus Neoplasms/pathology , Vascular Neoplasms/pathologyABSTRACT
No disponible
In 10%-15% of patients, myasthenia gravis is associated with thymoma. Because of its site, this tumour can have an un-noticed clinical history over a considerable time and be diagnosed when adjacent structures such as mediastinal vessels, heart or trachea become infiltrated. We present a patient with thymoma and infiltration of the superior vena cava, and which represents an incipient vena cava syndrome. The surgical treatment consisted of complete resection of the tumour including partial replacement of the vena cava with a pericardial patch. The surgery was complemented with radiotherapy
