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Pan Afr Med J ; 30: 301, 2018.
Article in English | MEDLINE | ID: mdl-30637085

ABSTRACT

The Kounis-Zavras syndrome is defined as the coincidental occurrence of acute coronary events and hypersensitivity reactions following an allergic reaction including a mast-cell degranulation of vasospastic mediators. This report describes a case of Kounis-Zavras syndrome in the setting of aspirin-induced asthma also known as Samter-Beer triad combining nasal polyps, asthma, and aspirin allergy leading to vasospasm and myocardial infarction. All physicians should be aware of The Kounis syndrome and always keep that unique clinical entity in mind to recognize it promptly and direct the therapy at suppressing the allergic reaction.


Subject(s)
Aspirin/adverse effects , Drug Hypersensitivity/physiopathology , Kounis Syndrome/diagnosis , Aspirin/administration & dosage , Asthma/chemically induced , Asthma/immunology , Drug Hypersensitivity/etiology , Drug Hypersensitivity/immunology , Female , Humans , Kounis Syndrome/physiopathology , Mast Cells/immunology , Middle Aged , Myocardial Infarction/chemically induced , Myocardial Infarction/immunology , Nasal Polyps/immunology
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