ABSTRACT
Purpose: Optical coherence tomography has emerged as an important intracoronary imaging technique for coronary artery disease diagnosis as it produces high-resolution cross-sectional images of luminal and plaque morphology. Precise and fast lumen segmentation is essential for efficient OCT morphometric analysis. However, due to the presence of various image artifacts, including side branches, luminal blood artifacts, and complicated lesions, this remains a challenging task. Approach: Our research study proposes a rapid automatic segmentation method that utilizes nonuniform rational B-spline to connect limited pixel points and identify the edges of the OCT lumen. The proposed method suppresses image noise and accurately extracts the lumen border with a high correlation to ground truth images based on the area, minimal diameter, and maximal diameter. Results: We evaluated the method using 3300 OCT frames from 10 patients and found that it achieved favorable results. The average time taken for automatic segmentation by the proposed method is 0.17 s per frame. Additionally, the proposed method includes seamless vessel reconstruction following the lumen segmentation. Conclusions: The developed automated system provides an accurate, efficient, robust, and user-friendly platform for coronary lumen segmentation and reconstruction, which can pave the way for improved assessment of the coronary artery lumen morphology.
ABSTRACT
The main objectives of this study are to investigate the spectral responses of a fire-damaged concrete slab using Impact-echo (IE) testing, and to develop a simplified model for interpreting the frequency shift due to heat-induced concrete damage after the fire. For these purposes, a reinforced concrete slab specimen (1000 mm (width) by 5000 mm (length) by 210 mm (thickness)) was fabricated in the laboratory. Heat damage in the concrete slab specimen was induced by exposing the bottom of the specimen to the temperatures corresponding to the standard fire curve described in the ASTM E 119 for 3 h. Impact-echo testing was performed on the bottom surface of the concrete slab specimen before and after inducing the fire damage. It was observed that the spectral responses of the fire-damaged concrete were dominated by several non-propagating waves, which resulted in main peak frequencies around 4500 Hz and 5100 Hz. A discrete layered concrete damage model developed in this study was used to reconstruct the variation of the P-wave velocity with the depth of the fire-damaged concrete. It was demonstrated that the predicted P-wave velocity profile using the simplified model showed a good agreement with the measured values from the five core samples, which measured 100 mm (diameter) by 200 mm (height) cylinders, using ultrasonic pulse velocity (UPV) measurements at eight different depths. In addition, the peak frequencies predicted by the simplified model were consistent with the measured peak frequencies. The experimental results in this study demonstrated that IE testing is effective for evaluating the post-fire damage of reinforced concrete slabs. Particularly, the simplified model in this study can be effective for better interpreting the spectral responses of fire-damaged concrete slabs by IE testing.
