Nutritional status and post-operative complications in patients undergoing surgery for advanced pharyngeal or laryngeal cancer.

PURPOSE: Malnutrition is an important prognostic indicator of post-operative outcomes in patients undergoing surgery for head and neck cancer, however, limited studies utilize validated nutrition assessment tools to accurately assess risk. The aim of this study was to determine the relationship between nutritional status on post-operative complications and length of stay for patients undergoing either a laryngectomy, pharyngectomy or pharyngolaryngectomy for head and neck cancer. METHODS: Patients with head and neck cancer undergoing a laryngectomy, pharyngectomy or pharyngolaryngectomy at a tertiary hospital in Australia were eligible for this retrospective cohort study (n = 40). Nutritional status was assessed by the dietitian on admission using the validated Subjective Global Assessment tool. Clinical outcomes were collected via retrospective chart review and included length of stay and post-operative complications. RESULTS: Pre-operative malnutrition incidence was 40%. Malnourished patients had higher incidences of any type of complication (57% vs 44%, p = 0.013) and pressure injury (86% vs 14%, p = 0.011) compared to well-nourished patients. Well-nourished patients had a clinically important shorter median length of stay compared to malnourished patients (17.5 vs 20 days). CONCLUSION: Early identification and management of malnutrition is essential to minimize risk of post-operative complications and reduce length of stay and should be considered a key component of prehabilitation programs.

Post-laryngectomy pulmonary and related symptom changes following adoption of an optimal day-and-night heat and moisture exchanger (HME) regimen.

BACKGROUND: This study examined post-laryngectomy pulmonary and related symptom changes following establishment of an optimal day/night regimen (all day/night wear of devices with improved humidification) using a new generation range of heat and moisture exchanger (HME) devices. METHODS: In Phase 1 (6 weeks), 42 post-laryngectomy HME users transitioned from their usual HME regime to equivalent new device/s (i.e., "like-for-like"). In Phase 2 (6 weeks) participants used the full range of HMEs to achieve an optimal day/night regimen. Pulmonary symptoms, device use, sleep, skin integrity, quality of life and satisfaction were examined at baseline, and weeks 2 and 6 of each Phase. RESULTS: From baseline to end of Phase 2, cough symptoms and impact significantly improved, as did sputum symptoms, sputum impact, duration and types of HMEs used, reasons for HME replacement, involuntary coughs, and sleep. CONCLUSION: The new HME range supported improved HME use, with pulmonary and related symptom benefits.

Management of leaking tracheoesophageal puncture with hyaluronic acid injection.

BACKGROUND: Tracheoesophageal puncture (TEP) with voice prosthesis is a widely used technique for voice restoration in laryngectomy and pharyngolaryngectomy patients. Complications include leakage around the prosthesis or a persistent TEP postremoval of the prosthesis. METHODS: We describe a method for managing leakage around voice prosthesis or persistent TEP using hyaluronic acid injection. We also present a retrospective audit of our practice. RESULTS: This study had 8 patients who were treated over a 32-month period. All cases had immediate cessation of salivary leak. Duration of efficacy was variable. Five of the 8 cases had permanent resolution of their symptoms after multiple injections. Two cases of persistent TEP were treated surgically after multiple injections. One patient with peripheral leakage continues to have regular injections. CONCLUSION: Hyaluronic acid injection in the treatment of persistent TEP or peripheral leak around a voice prosthesis is a useful treatment option to provide immediate and occasionally long-lasting relief from symptoms.