ABSTRACT
Faulty messaging between organs could make us old.
ABSTRACT
Scientists make partially synthetic version of moss chromosome, aiming to harness plant for industry.
Subject(s)
Bryopsida , Chromosomes, Artificial , Genome, Plant , Bryopsida/genetics , IndustryABSTRACT
Viral protein prods nerve cells, may be treatment target.
Subject(s)
COVID-19 , Coronavirus Papain-Like Proteases , Nociceptors , SARS-CoV-2 , Sneezing , Humans , COVID-19/physiopathology , SARS-CoV-2/enzymology , Animals , Mice , Nociceptors/virologyABSTRACT
Human Immunome Project's survey aims to improve drugs and vaccines.
Subject(s)
Biological Variation, Population , Drug Development , Immunity , Vaccine Development , Humans , Hepatitis B Vaccines/immunology , Biological Variation, Population/immunology , International CooperationABSTRACT
Bladder cancer results suggest that after decades of failure, the viruses could finally reach their potential.
Subject(s)
Oncolytic Virotherapy , Oncolytic Viruses , Urinary Bladder Neoplasms , Humans , Urinary Bladder Neoplasms/therapy , Oncolytic Virotherapy/methods , Clinical Trials as Topic , Adenoviridae/genetics , Microorganisms, Genetically-Modified/genetics , Herpesvirus 1, Human/geneticsABSTRACT
Cells can survive when nearly half their chromosomes are humanmade.
Subject(s)
Chromosomes, Artificial, Yeast , Genes, Synthetic , Genome, Fungal , Saccharomyces cerevisiae , Saccharomyces cerevisiae/geneticsABSTRACT
Agency launches major effort to explore importance of accumulating mutations in somatic cells.
Subject(s)
Genome, Human , Human Body , Mosaicism , Humans , Genome, Human/genetics , National Institutes of Health (U.S.)ABSTRACT
Clinical trials will gauge whether GLP-1 analogs curb drug and alcohol cravings.
Subject(s)
Anti-Obesity Agents , Behavior, Addictive , Glucagon-Like Peptide 1 , Substance-Related Disorders , Humans , Alcoholism/drug therapy , Anti-Obesity Agents/pharmacology , Anti-Obesity Agents/therapeutic use , Behavior, Addictive/drug therapy , Glucagon-Like Peptide 1/analogs & derivatives , Glucagon-Like Peptide 1/pharmacology , Glucagon-Like Peptide 1/therapeutic use , Substance-Related Disorders/drug therapyABSTRACT
New view of molecule's good side inspires plans to test it as treatment for a variety of illnesses.
Subject(s)
Anti-Inflammatory Agents , Antioxidants , Bilirubin , Bilirubin/pharmacology , Bilirubin/therapeutic use , Bilirubin/toxicity , Antioxidants/pharmacology , Antioxidants/therapeutic use , Antioxidants/toxicity , Anti-Inflammatory Agents/pharmacology , Anti-Inflammatory Agents/therapeutic use , Anti-Inflammatory Agents/toxicity , Humans , AnimalsABSTRACT
Mock embryos created by multiple groups recapitulate developmental events beyond implantation.
Subject(s)
Blastocyst , Embryo Implantation , Embryo Research , Embryonic Development , Stem Cells , HumansABSTRACT
Decades after faltering, angiogenesis inhibitors show new promise when paired with checkpoint drugs.
Subject(s)
Angiogenesis Inhibitors , Immune Checkpoint Inhibitors , Neoplasms , Humans , Angiogenesis Inhibitors/therapeutic use , Immune Checkpoint Inhibitors/therapeutic use , Neoplasms/drug therapy , Drug Therapy, CombinationABSTRACT
First embryo mimics from monkeys may boost research into early development, miscarriages.
Subject(s)
Abortion, Spontaneous , Embryo, Mammalian , Macaca fascicularis , Models, Animal , Female , Humans , Pregnancy , Animals , Embryonic Stem CellsABSTRACT
$11.3 billion would go to treatment, testing, and education.
Subject(s)
Disease Eradication , Financing, Government , Hepatitis C , Humans , Budgets , Hepatitis C/diagnosis , Hepatitis C/epidemiology , Hepatitis C/prevention & control , Disease Eradication/economics , United States/epidemiology , Diagnostic Techniques and Procedures , Patient Education as Topic , Financing, Government/legislation & jurisprudenceABSTRACT
Lipids called ceramides may be better predictors of cardiovascular problems than cholesterol. Doctors and pharma are waking up to their potential.
Subject(s)
Cardiovascular Diseases , Ceramides , Humans , Cardiovascular Diseases/blood , Cardiovascular Diseases/diagnosis , Cardiovascular Diseases/metabolism , Ceramides/blood , Ceramides/metabolism , Cholesterol/blood , Hematologic TestsABSTRACT
Technique is designed to treat mitochondrial disease.
Subject(s)
Hematopoietic Stem Cell Transplantation , Mitochondria , Mitochondrial Diseases , Humans , Child , Mitochondrial Diseases/therapy , Hematopoietic Stem CellsABSTRACT
Thousands of phages appear to have stolen the gene-cutting mechanism.
Subject(s)
Bacteriophages , CRISPR-Cas Systems , Gene Editing , Bacteriophages/geneticsABSTRACT
SARS-CoV-2 wields versatile proteins to foil our immune system's counterattack.
Subject(s)
COVID-19 , SARS-CoV-2 , Viral Proteins , Humans , COVID-19/immunology , SARS-CoV-2/immunology , Viral Proteins/immunologyABSTRACT
Modified cells don't allow invaders to replicate and don't share DNA.
Subject(s)
Codon, Terminator , Coliphages , Escherichia coli , Virus Replication , Coliphages/genetics , Coliphages/physiology , Escherichia coli/genetics , Escherichia coli/virology , Virus Replication/geneticsABSTRACT
Bioreactor lets "embryoids" mature long enough for multiple organs to form.
