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3.
Pharmazie ; 55(6): 436-9, 2000 Jun.
Article in German | MEDLINE | ID: mdl-10907251

ABSTRACT

Dissociation constants of phenoles aminomethylated once or twice were determined using UV spectrometric titration. Pka values were computed by non linear regression; correlation coefficients show that experimental data and calculated curves fit well.


Subject(s)
Phenols/analysis , Spectrophotometry, Ultraviolet , Hydrogen-Ion Concentration , Regression Analysis
4.
Pharmazie ; 55(1): 22-6, 2000 Jan.
Article in German | MEDLINE | ID: mdl-10683866

ABSTRACT

4,5-Dihydro 1,2,4-oxadiazoles can be synthesized from aromatic and araliphatic amidoximes by cyclocondensation with aldehydes and ketones. Resulting heterocycles differ in substitution at C-3 and C-5 showing the scope of the simple reaction.


Subject(s)
Aldehydes/chemistry , Ketones/chemistry , Oxadiazoles/chemical synthesis , Oximes/chemistry
7.
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