ABSTRACT
O trabalho descreve o instrumento implantado em 2013 em 86 Unidades Básicas de Saúde da CRS Norte, município de São Paulo, para seguimento das mulheres com lesões precursoras de Câncer de Colo de Útero detectadas no rastreamento através do exame Papanicolaou. Todas as ações, exames, consultas médicas ou de enfermagem, VD, contato (por telefone outros), faltas, são registradas no instrumento até que o tratamento seja concluído (AU).
Subject(s)
Humans , Uterine Cervical Neoplasms , Uterine Cervical Neoplasms/diagnosis , Uterine Cervical Neoplasms/prevention & controlABSTRACT
O trabalho descreve o instrumento implantado em 2013 em 86 Unidades Básicas de Saúde da CRS Norte, município de São Paulo, para seguimento das mulheres com lesões precursoras de Câncer de Colo de Útero detectadas no rastreamento através do exame Papanicolaou. Todas as ações, exames, consultas médicas ou de enfermagem, VD, contato (por telefone outros), faltas, são registradas no instrumento até que o tratamento seja concluído .
Subject(s)
Humans , Uterine Cervical Neoplasms , Uterine Cervical Neoplasms/diagnosis , Uterine Cervical Neoplasms/prevention & controlSubject(s)
Glycoproteins/metabolism , Submandibular Gland/metabolism , Animals , Autoradiography , Cell Nucleus/ultrastructure , Cytoplasmic Granules/metabolism , Cytoplasmic Granules/ultrastructure , Endoplasmic Reticulum/ultrastructure , Fucose/metabolism , Golgi Apparatus/metabolism , Golgi Apparatus/ultrastructure , Male , Mice , Mitochondria/ultrastructure , Submandibular Gland/ultrastructureSubject(s)
Bronchi/metabolism , Mucins/analysis , Trachea/metabolism , Animals , Histocytochemistry , HorsesABSTRACT
Glycoprotein secretion in the mouse submandibular gland was investigated by light microscope radioautography of semi-thin sections after the administration of L-3H-fucose. The incorporation of the precursor in the acini was negligible. 3H-fucose was taken up in the paranuclear region of the cells lining the intercalated, secretory, striated and excretory ducts. This labeling pattern was interpredted as addition of the precursor to glycoproteins within the Golgi apparatus. Incoropration in the intercalated duct was restricted to the cells with fine cytoplasmic granules. The glycoproteins synthesized by the intercalated and secretory ducts were transported to the saliva by the secretion granules. It is assumed that the glycoproteins synthesized in the striated and excretory ducts are plasma membrane glycoproteins which seem to renew continuously. Quantitation of the radioautographs supplied data concerning the incorporation of 3H-fucose into newly synthesized glycoproteins as well as the renewal of the labeled macromolecules in each duct.