1.
Head Neck Pathol
; 18(1): 43, 2024 May 13.
Article
in English
| MEDLINE
| ID: mdl-38735907
ABSTRACT
Cribriform adenocarcinoma of the salivary gland (CASG) is an entity that is currently classified under polymorphous adenocarcinoma (PAC), cribriform subtype per the 2022 WHO classification of head and neck tumours. There is debate about whether CASG should be considered a separate diagnostic entity, as CASG differs from conventional PAC in anatomic site, clinical behaviors, and molecular patterns. Herein we describe a challenging and unique case which shares histologic and behavioral features between CASG and conventional PAC with a YLPM1::PRKD1 rearrangement not previously reported in the literature.
Subject(s)
Adenocarcinoma , Oncogene Proteins, Fusion , Salivary Gland Neoplasms , Female , Humans , Male , Middle Aged , Adenocarcinoma/genetics , Adenocarcinoma/pathology , Gene Fusion , Oncogene Proteins, Fusion/genetics , Protein Kinase C/genetics , Salivary Gland Neoplasms/genetics , Salivary Gland Neoplasms/pathology , RNA-Binding Proteins/genetics , Repressor Proteins/genetics
2.
Am J Respir Crit Care Med
; 209(12): 1501-1504, 2024 06 15.
Article
in English
| MEDLINE
| ID: mdl-38652140