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1.
Orthop Surg ; 9(2): 180-185, 2017 May.
Article in English | MEDLINE | ID: mdl-28598560

ABSTRACT

OBJECTIVE: To assess the benefits of use of a tourniquet in one limb in patients undergoing simultaneous bilateral total knee arthroplasty (TKA). METHODS: A prospective randomized trial was designed to evaluate the outcomes of unilateral tourniquet use during simultaneous bilateral TKA. A total of 52 (36 women and 16 men) patients with osteoarthritis who underwent simultaneous bilateral primary TKA between January 2010 and January 2015 were assigned randomly to tourniquet (TG) or non-tourniquet (NG) groups prior to surgery. Operating time, pain score, range of motion, first active straight-leg raise time, swelling, wound healing, deep vein thrombosis, and Knee Society score were observed. RESULTS: Mean operating time in the TG group was shorter than that in the NG group (P < 0.05). Postoperative pain was measured by a visual analog scale (VAS) and straight-leg raise time, which was lower and shorter in limbs operated without the use of a tourniquet (P < 0.05). In addition, this group had less postoperative swelling and lower incidence of wound complications in the early postoperative period (P < 0.05). There was no significant difference in the range of motion (ROM), deep venous thrombosis incidence, and Knee Society scores between the two groups. CONCLUSIONS: Tourniquet use in bilateral TKA can reduce intraoperative time but was associated with a higher incidence of wound complications and larger postoperative knee swelling.


Subject(s)
Arthroplasty, Replacement, Knee/instrumentation , Osteoarthritis, Knee/surgery , Tourniquets , Aged , Arthroplasty, Replacement, Knee/methods , Blood Loss, Surgical/statistics & numerical data , Female , Humans , Male , Middle Aged , Operative Time , Osteoarthritis, Knee/physiopathology , Postoperative Complications , Prospective Studies , Range of Motion, Articular/physiology , Venous Thrombosis/prevention & control , Wound Healing/physiology
2.
Orthopedics ; 37(10): 685-90, 2014 Oct.
Article in English | MEDLINE | ID: mdl-25275969

ABSTRACT

Vascularization of tissue-engineered bones is critical to achieving satisfactory repair of bone defects. The authors investigated the use of prevascularized tissue-engineered bone for repairing bone defects. The new bone was greater in the prevascularized group than in the non-vascularized group, indicating that prevascularized tissue-engineered bone improves the repair of bone defects. [Orthopedics. 2014; 37(10):685-690.].


Subject(s)
Bioreactors , Bone Regeneration , Bone and Bones/surgery , Femur/surgery , Tissue Engineering , Animals , Bone Marrow Cells , Bone Transplantation , Bone and Bones/blood supply , Coculture Techniques , Endothelial Cells , Femur/injuries , Mesenchymal Stem Cells , Models, Animal , Osteoblasts , Sheep , Tissue Scaffolds
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