Conductas de riesgo asociadas con el inicio sexual temprano en adolescentes en México.

OBJETIVO: Analizar factores asociados con el inicio sexual temprano (IST) en mujeres y hombres de 15 a 19 años. Material y métodos. Utilizando información de adolescentes de la Encuesta Nacional de Salud y Nutrición 2022, se examina el IST (<15 años). Mediante un enfoque ecológico se ajustaron modelos probit multivariados por sexo para explorar factores sociodemográficos, psicosociales y de comportamiento sexual asociados con IST. RESULTADOS: Mujeres residentes en la región Pacífico-Centro y Pacífico-Sur, así como aquellas con pareja sexual de mayor edad por cinco años o más y hombres con estrato socioeconómico medio, tienen mayor probabilidad de IST que sus contrapartes de la región Pacífico-Norte, diferencia de edad con la pareja menor a cinco años y estrato bajo, respectivamente. Conclusión. Debido a que el IST en adolescentes está determinado por el contexto sociodemográfico y desigualdades de género, para una sexualidad saludable se requiere garantizar educación integral en sexualidad y servicios de salud de calidad.

Utilización de servicios preventivos de salud sexual y reproductiva antes y durante la pandemia de Covid-19 en México.

OBJETIVO: Analizar la utilización de servicios preventivos de salud sexual y reproductiva (SPSSR) en mujeres y hombres adultos antes y durante la pandemia Covid-19 y características sociodemográficas asociadas. Material y métodos. Usando la Encuesta Nacional de Salud y Nutrición 2018-19, 2021 y 2022 se analizó información sobre las pruebas realizadas de Papanicolaou y VPH, exploración clínica de mamas, mastografía, antígeno prostático y tacto rectal. Se construyeron modelos logísticos multivariados estratificados por sexo para explorar la asociación entre la utilización de los SPSSR y variables seleccionadas. RESULTADOS: Desde antes de la pandemia se observan bajas prevalencias en procedimientos diagnósticos, particularmente en hombres, que se agudizaron durante la emergencia sanitaria. La población con un perfil sociodemográfico más favorecido presenta mayor posibilidad de utilizar SPSSR; asimismo, se observan inequidades de género en algunas características. Conclusión. La experiencia de la pandemia puso de manifiesto la necesidad de mejorar y fortalecer los SPSSR para lograr una mayor eficiencia.

Salud sexual y reproductiva en población adolescente y adulta en México, 2022.

OBJETIVO: Caracterizar la situación de la salud sexual y reproductiva (SSR) en población adolescente (10-19) y adulta (20-49). Material y métodos. Utilizando la Encuesta Nacional de Salud y Nutrición 2022, se estimaron prevalencias e intervalos de confianza al 95% para indicadores de SSR. RESULTADOS: En adolescentes, 73.2% ha escuchado hablar de anticonceptivos, 88.1% saben que el condón se usa una sola vez y 60.4% que previene embarazos e infecciones de transmisión sexual; 22.8% ha iniciado vida sexual y 73.2% usaron condón en la primera relación sexual. En la población adulta, 42.7 y 38.0% no usaron protección en la primera y última relación sexual y 53.4 y 40.7% usaron condón en la primera y última relación sexual. Se encontraron diferencias en la atención de la salud materna entre adolescentes y adultas. Conclusión. Contar con información actualizada en SSR permite focalizar la atención en las necesidades de las personas.

Adolescent use of outpatient health services in Mexico: their health needs and associated factors.

OBJECTIVE: To estimate adolescent use of outpatient services, identifying their health needs and associated socioeconomic factors. MATERIALS AND METHODS: Using data from Ensanut 2018-2019, adolescents (ages 10-19) with health needs and those receiving care from health personnel (users) were identified. Needs were analyzed by sex and socioeconomic status (SES). Logistic models were used to assess the factors associated with the use of health care and choice of provider. RESULTS: 6% of adolescents reported health needs, of whom 64% used outpatient services. Respiratory and gastrointestinal infections were the principal health needs prompting use of services overall. However, by SES, motivations centered on pregnancy for the poor and accidental injuries for the wealthy. One in three adolescents with health needs, particularly the poorest, received no care. Living with a partner and having health insurance were the main predictors of use. Greater schooling among household heads and higher SES correlated with the use of private services. CONCLUSIONS: Despite being aware of their health needs, adolescents are the group that uses health services the least in Mexico. Promoting preventative and timely treatment for this population would encourage youths to seek care more often.

Proceso de implementación de una iniciativa de atención a mujeres en postaborto en Chile, 2016-2020 / The implementation process of a post-abortion healthcare initiative in Chile, 2016-2020

Objetivo: Analizar el proceso de implementación de una iniciativa de calidad de atención en el postaborto en tres hospitales de Santiago de Chile para su posterior escalamiento al ámbito nacional. Método: Se efectuó un estudio cualitativo, con base en una revisión documental sustentada en documentos normativos emitidos por el Ministerio de Salud y 23 entrevistas semiestructuradas a tomadores de decisiones, profesionales de salud y usuarias. Se realizó un análisis de contenido usando el programa Atlas-ti 8. Resultados: A nivel normativo, se identificaron acciones relacionadas con la implementación de la iniciativa, y a nivel de proceso se identificaron los aciertos, las dificultades y las resistencias que experimentaron los equipos involucrados en el piloto durante su implementación. A pesar de que la implementación de la iniciativa no fue planificada, tuvo efectos positivos para el bienestar de las mujeres y el desempeño de los profesionales de atención implicados en el proceso. Conclusiones: Esta experiencia es un punto de partida para planear la implementación nacional con base en estrategias bien definidas. Los resultados aportan una experiencia documentada para quienes desean desarrollar iniciativas o programas de atención a mujeres en situación de postaborto.

Objective: To analyze the implementation process of a quality post-abortion care initiative in three hospitals in Santiago de Chile for its subsequent scale up at the national level. Method: A qualitative study was carried out, based on a documentary review supported by governmental normative documents issued by the Ministry of Health and 23 semi-structured interviews with decision-makers, health providers and users. Content analysis was performed using the Atlas-ti 8 software. Results: At the regulatory level, actions related to the implementation of the initiative were identified, and at the process level, the success, difficulties and resistance experienced by the teams involved in the pilot during its implementation were identified. Although the implementation of the initiative was not planned, it had positive effects on the well-being of the women and the performance of the care providers involved in the process. Conclusions: This experience is a starting point to plan implementation at the national level with well-defined strategies. Our results provide a documented experience for those who wish to develop post-abortion care initiatives or programs.

PLA/modified-starch blends and their application for the fabrication of non-woven fabrics by melt-blowing.

Blends of polylactic acid (PLA) and thermoplastic starch (TS) with and without chemical modification were obtained by melt extrusion and used to obtain non-woven fabrics by melt-blowing for the first time. Different TS were obtained by reactive extrusion from native cassava, oxidized, maleated, and dual modified (oxidized and maleated) starch. The chemical modification of starch decreases the difference in viscosity and favors blending, resulting in more homogeneous morphologies, unlike the blends with unmodified TS, which displayed a visible phase separation with large TS droplets. The dual modified starch showed a synergistic effect to process TS by melt-blowing. Regarding non-woven fabrics, values in diameter (2.5-82.1 µm), thickness (0.4-0.6 mm), and grammage (49.9-103.8 g/m2) were explained due to differences in viscosity of the components, and to the fact that during melt the hot air preferentially stretches and thins the areas without large droplets of TS. Moreover, plasticized starch acts as a flow modifier. The porosity of the fibers increased with the addition of TS. Further studies and optimization of blends with low contents of TS and type starch modification will be necessary to completely understand these systems with very complex behavior to obtain non-woven fabrics with improved properties and application.

Severe Adverse Maternal and Neonatal Outcomes in Adolescent Mother-Newborn Dyads: A Multicentre Study in Latin America.

OBJECTIVES: To compare the risk of severe adverse maternal outcomes (SMO) and neonatal outcomes (SNO) and analyse their maternal correlates in adolescent mother-newborn and young mother-newborn dyads in secondary and tertiary care users in Latin America. METHODS: We performed a secondary analysis of the WHO Multicountry Survey on Maternal and Newborn Health database in 83 secondary and tertiary hospitals in seven countries in Latin America. We constructed a composite indicator of both SMO and SNO and estimated odds ratios (OR) comparing adolescent mothers (aged 12-19) with young mothers (aged 20-24). Our unit of analysis was the mother-newborn dyad. RESULTS: We found that the combination of SMO and SNO was three times more likely in adolescent mother as compared to young mother dyads (OR 3.56; 95% CI 1.67-7.59). SNO either alone or in combination with SMO were more likely in adolescents aged 12 to 16 than in young women (OR 1.27 and 4.87, respectively). CONCLUSIONS FOR PRACTICE: Adolescent mothers and their newborns are at an increased risk of severe adverse outcomes during child birth and in the first week postpartum compared to young mother dyads, especially young adolescents. Focusing on the dyad as a whole may facilitate a step towards integrated care which maximizes the health benefits of both mother and newborn. Continued efforts are needed to improve health care and prevention initiatives directed towards adolescent women and their newborns in Latin America.

Cervical Cancer Prevention in El Salvador: Gains to Date and Challenges for the Future.

Cervical cancer is preventable through vaccination, early detection, and the treatment of pre-cancerous lesions. However, global inequalities mean that the disease remains a leading cause of cancer death around the world, with over 80% of new cases and 90% of deaths occurring in low- and middle-income countries (LMICs). In El Salvador, joint efforts between the Ministry of Health (MoH) and the non-profit organization Basic Health International (BHI) have been in place since 2008, with the goal of reducing the country's disease burden. While the World Health Organization's (WHO) call to action to eliminate cervical cancer provided worldwide momentum to implement new public health initiatives, the COVID-19 pandemic disrupted ongoing programs and jeopardized plans for the future. The purpose of this manuscript is to describe the progress that El Salvador has achieved in improving cervical cancer prevention, the impact of the pandemic on current strategies, and potential solutions that can help the country meet the WHO's strategic targets by 2030 to accelerate the elimination of cervical cancer.

Outcomes of transitional care programs on adolescent chronic inflammatory systemic diseases: systematic review and meta-analyses.

BACKGROUND: Patients with juvenile chronic inflammatory systemic diseases (jCID) are vulnerable to many circumstances when transitioning to adult-centered healthcare; this increases the burden of disease and worsen their quality of life. METHODS: MEDLINE, Embase, Web of Science and Scopus were searched from inception to March 16th, 2021. We included observational, randomized controlled trials and quasi-experimental studies that evaluated a transitional care program for adolescents and young adults with jCIDs. We extracted information regarding health-related quality of life, disease activity, drop-out rates, clinical attendance rates, hospital admission rates, disease-related knowledge, surgeries performed, drug toxicity and satisfaction rates. RESULTS: Fifteen studies met our inclusion criteria. The implementation of transition programs showed a reduction on hospital admission rates for those with transition program (OR 0.28; 95% CI 0.13 to 0.61; I 2 = 0%; p = 0.97), rates of surgeries performed (OR 0.26; 95% CI 0.12 to 0.59; I 2 = 0%; p = 0.50) and drop-out rates from the adult clinic (OR 0.23; 95% CI 0.12 to 0.46; I 2 = 0%; p = 0.88). No differences were found in other outcomes. CONCLUSION: The available body of evidence supports the implementation of transition programs as it could be a determining factor to prevent hospital admission rates, surgeries needed and adult clinic attendance rates.

Continuum of care for maternal, newborn and child health: Evidence from a national survey in Mexico.

OBJECTIVE: To compare coverage of maternal, newborn and child health (MNCH) continuum of care between women who had experienced adolescent maternity (AM) and those who had not. METHODS: Using a Mexican probabilistic survey representative at the national level (ENSANUT 2018-19), we developed a cross-sectional analysis of 1,768 women aged 12 to 49 years who had a child within five years before the interview. We used modified Poisson models to estimate prevalence ratios (PRs) and independent and conditional coverage levels based on the probability estimates yielded by these models at different stages of maternal-newborn care process. RESULTS: PRs for the MNCH continuum of care were approximately 40% lower for women who had experienced AM compared to those who had not (95%CI:0.35, 1.14). The coverage for the MNCH continuum of care was only 7.4% [95%CI: 3.5, 11.2] and 11.7% [95%CI: 9.3, 14.1] in women who had/not experienced AM, respectively. CONCLUSIONS: The provision of a continuum of care for mothers and their children can be achieved through a combination of well-defined policies and strategies that improve health care practices and services throughout the life cycle. It is necessary to expand the coverage and quality of care, which will provide the opportunity to shift the focus from vertical programs to integrated continuous care. Policy makers must implement interventions that are consistent with specific problems of population and health-care providers. Our analysis highlights the deficiencies in the care process, making this study a useful reference for countries with similar characteristics.

[Characterization of gas exchange parameters in Mexico City]. / Caracterización de parámetros del intercambio gaseoso en la Ciudad de México.

Background: At high altitude the gas exchange is impaired, in the moderate altitude of Mexico City they are not yet defined. Objective: To characterize the gas exchange in the moderate altitude of Mexico City. Material and methods: Through an analytical cross-sectional study, subjects born and inhabitants of Mexico City, both genders, aged 20 to 59 years without cardiopulmonary disease, were studied. Their demographic variables, simple spirometry and arterial blood gas were recorded. Differences in variables were calculated with one-way ANOVA for independent groups and Bonferroni adjustment. p < 0.05 was accepted as significant. Results: 335 subjects were studied, 168 (50.15%) men. Group age 45 ± 11 years old, body mass index 22.97 ± 1.54 Kg/m2. Forced expiratory volume ratio in the first second / Forced vital capacity (FEV1/FVC) 91.58 ± 12.86%. The arterial oxygen pressure was: 66 ± 5.02 mmHg, carbon dioxide: 32.07 ± 2.66 mmHg, arterial oxygen saturation: 93.0 3 ± 1.80%, and hemoglobin: 14.07 ± 1.52 gr/dL. Conclusions: The arterial oxygen pressure and carbon dioxide are lowered at the Mexico City altitude.

Introducción: en las grandes altitudes, el intercambio gaseoso suele estar deteriorado; en la altitud moderada de la Ciudad de México esto no está aún plenamente definido. Objetivo: caracterizar el intercambio gaseoso en la altitud moderada de la Ciudad de México. Material y métodos: mediante un estudio transversal analítico se estudiaron sujetos nacidos y habitantes de la Ciudad de México, de ambos géneros, con edades de 20 a 59 años sin enfermedad cardiopulmonar. Se registraron sus variables demográficas, espirometría simple y de gasometría arterial. Las diferencias en las variables se calcularon con ANOVA de una vía para grupos independientes y ajuste de Bonferroni. Una p < 0.05 se aceptó como significativa. Resultados: se estudiaron 335 sujetos, de los cuales 168 (50.15%) fueron hombres, la edad grupal fue de 45 ± 11 años, con índice de masa corporal 22.97 ± 1.54 Kg/m2. La relación volumen espiratorio forzado en el primer segundo/ Capacidad vital forzada (VEF1/CVF) de 91.58 ± 12.86%. La presión arterial de oxígeno fue de 66 ± 5.02 mmHg, el bióxido de carbono: 32.07 ± 2.66 mmHg, la saturación arterial de oxígeno: 93.03 ± 1.80% y la hemoglobina: 14.07 ± 1.52 gr/dL. Conclusiones: la presión arterial de oxígeno y del bióxido de carbono están disminuidos a la altura de la Ciudad de México.

Caracterización de parámetros del intercambio gaseoso en la Ciudad de México / Characterization of gas exchange parameters in Mexico City

Introducción: en las grandes altitudes, el intercambio gaseoso suele estar deteriorado; en la altitud moderada de la Ciudad de México esto no está aún plenamente definido. Objetivo: caracterizar el intercambio gaseoso en la altitud moderada de la Ciudad de México. Material y métodos: mediante un estudio transversal analítico se estudiaron sujetos nacidos y habitantes de la Ciudad de México, de ambos géneros, con edades de 20 a 59 años sin enfermedad cardiopulmonar. Se registraron sus variables demográficas, espirometría simple y de gasometría arterial. Las diferencias en las variables se calcularon con ANOVA de una vía para grupos independientes y ajuste de Bonferroni. Una p < 0.05 se aceptó como significativa. Resultados: se estudiaron 335 sujetos, de los cuales 168 (50.15%) fueron hombres, la edad grupal fue de 45 ± 11 años, con índice de masa corporal 22.97 ± 1.54 Kg/m2. La relación volumen espiratorio forzado en el primer segundo/Capacidad vital forzada (VEF1/CVF) de 91.58 ± 12.86%. La presión arterial de oxígeno fue de 66 ± 5.02 mmHg, el bióxido de carbono: 32.07 ± 2.66 mmHg, la saturación arterial de oxígeno: 93.03 ± 1.80% y la hemoglobina: 14.07 ± 1.52 gr/dL. Conclusiones: la presión arterial de oxígeno y del bióxido de carbono están disminuidos a la altura de la Ciudad de México.

Background: At high altitude the gas exchange is impaired, in the moderate altitude of Mexico City they are not yet defined. Objective: To characterize the gas exchange in the moderate altitude of Mexico City. Material and methods: Through an analytical cross-sectional study, subjects born and inhabitants of Mexico City, both genders, aged 20 to 59 years without cardiopulmonary disease, were studied. Their demographic variables, simple spirometry and arterial blood gas were recorded. Differences in variables were calculated with one-way ANOVA for independent groups and Bonferroni adjustment. p < 0.05 was accepted as significant. Results: 335 subjects were studied, 168 (50.15%) men. Group age 45 ± 11 years old, body mass index 22.97 ± 1.54 Kg/m2. Forced expiratory volume ratio in the first second / Forced vital capacity (FEV1/FVC) 91.58 ± 12.86%. The arterial oxygen pressure was: 66 ± 5.02 mmHg, carbon dioxide: 32.07 ± 2.66 mmHg, arterial oxygen saturation: 93.0 3 ± 1.80%, and hemoglobin: 14.07 ± 1.52 gr/dL. Conclusions: The arterial oxygen pressure and carbon dioxide are lowered at the Mexico City altitude.

Design of a multifaceted strategy based on automated text messaging in patients with recent heart failure admission.

AIMS: To evaluate a telemonitoring strategy based on automated text messaging and telephone support after heart failure (HF) hospitalization. METHODS AND RESULTS: The MESSAGE-HF study is a prospective multicentre, randomized, nationwide trial enrolling patients from 30 clinics in all regions of Brazil. HF patients with reduced left ventricular ejection fraction (<40%) and access to mobile phones are eligible after an acute decompensated HF hospitalization. Patients meeting eligibility criteria undergo an initial feasibility text messaging assessment and are randomized to usual care or telemonitoring intervention. All patients receive a HF booklet with basic information and recommendations about self-care. Patients in the intervention group receive four daily short text messages (educational and feedback) during the first 30 days of the protocol to optimize self-care; the feedback text messages from patients could trigger diuretic adjustments or a telephone call from the healthcare team. After 30 days, the frequency of text messages can be adjusted. Patients are followed up after 30, 90, and 180 days, with final status ascertained at 365 days by telephone. Our primary endpoint is the change in N-terminal pro-brain natriuretic peptide (NT-proBNP) levels after 180 days. Secondary endpoints include changes in NT-proBNP after 30 days; health-related quality of life, HF self-care, and knowledge scales after 30 and 180 days; and a composite outcome of HF hospitalization and cardiovascular death, adjudicated by a blinded and independent committee. CONCLUSIONS: The MESSAGE-HF trial is evaluating an educational and self-care promotion strategy involving a simple, intensive, and tailored telemonitoring system. If proven effective, it could be applied to a broader population worldwide.

Prevalence of suicidality, depression, post-traumatic stress disorder, and anxiety among female sex workers: a systematic review and meta-analysis.

The purpose was to assess prevalence of suicidality, depression, post-traumatic stress disorder (PTSD), and anxiety among female sex workers (FSW). A systematic review and meta-analysis was performed. Search strategy was performed in MEDLINE, Scopus, Web of Science, EMBASE, Ovid and Cochrane Central Database from inception until March 2020. Considered for inclusion were cross-sectional studies performed on FSW that assessed prevalence of any of the following: suicide attempt or suicidal ideation, depression, PTSD, or anxiety. Five reviewers, independently and in duplicate, selected all eligible articles in an abstract and full-text screening phase and, moreover, extracted information from each study. A binomial-normal generalized linear mixed model was employed to estimate prevalence of the conditions. From 8035 studies yielded in the search strategy, 55 were included for analysis. The overall prevalence of suicidal ideation and attempt was 27% (95% C.I. 18-39%) and 20% (95% C.I. 13-28%), respectively. Furthermore, overall prevalence of depression and PTSD was 44% (95% C.I. 35-54%) and 29% (95% C.I. 18-44%), respectively. Eleven studies were classified as high quality. Findings indicate that there is an overall high prevalence of suicidality, depression, and PTSD among FSW. Development of accessible large-scale interventions that assess mental health among this population remains critical.

[Deterioration of gas exchange in subjects with an increase in body mass index at an altitude of 2,240 meters above sea level]. / Deterioro del intercambio gaseoso en sujetos con incremento del índice de masa corporal a una altitud de 2,240 metros sobre el nivel del mar.

Introducción: Las alteraciones del intercambio gaseoso se han reconocido en la obesidad mórbida; sin embargo, no se conoce su comportamiento conforme se incrementa el índice de masa corporal. Objetivo: Conocer el comportamiento del intercambio gaseoso a la altura de la Ciudad de México en el desarrollo de obesidad mórbida. Métodos: Mediante un diseño transversal analítico se estudió a sujetos pareados por género y edad de cuatro grupos diferentes de índice de masa corporal (kg/m2): normal (18.5-24.9), sobrepeso (25-29.9), obesidad (30-39.9) y obesidad mórbida (≥ 40). Se obtuvieron sus antecedentes patológicos y demográficos, variables de gasometría arterial y espirometría simple. Las variables se determinaron de acuerdo con las características de la muestra; las diferencias entre grupos se realizaron mediante Anova de una vía con ajuste de Bonferroni, así como la correlación de Pearson para las variables relacionadas. Una p < 0.05 se consideró con significación estadística. Resultados: Se estudió a 560 pacientes en cuatro grupos. La edad promedio fue de 49 ± 11 años. La mayor frecuencia de diabetes mellitus (34.29%), hipertensión arterial (50%) e hiperlipidemia (36.43%) se registró en el grupo de obesidad, y la de roncador (73.57%) en la obesidad mórbida. Se identificaron diferencias desde el grupo normal respecto de la obesidad mórbida: PaCO2 31.37 ± 2.08 vs. 38.14 ± 5.10 mmHg; PaO2 68.28 ± 6.06 vs. 59.86 ± 9.28 mmHg y SaO2 93.51 ± 1.93 vs. 89.71 ± 5.37%, todas con p = 0.0001. Correlación IMC-PaCO2: 0.497, e IMC-PaO2: -0.365, p = 0.0001, respectivamente. Conclusiones: A la altitud de la Ciudad de México y con índice de masa corporal > 30 kg/m2, las variables relacionadas con el intercambio gaseoso y espirometría simple comienzan a deteriorarse; son evidentes con IMC > 40 kg/m2. Introduction: Alterations of gas exchange have been recognized in morbid obesity, however, it is not known how their behavior would be as the body mass index increases. Objective: To know the behavior of gas exchange at the level of Mexico City in the development of morbid obesity. Methods: Through analytical design, subjects matched by gender and age were studied from four different groups of body mass index (kg/m2), normal (18.5-24.9), overweight (25-29.9), obesity (30-39.9) and morbid obesity (≥ 40). Their pathological and demographic antecedents, arterial blood gas and simple spirometry variables were obtained. The variables were shown according to their sample characteristic. The differences between groups were made using one way Anova with Bonferroni adjustment, as well as Pearson's correlation for the related variables. Statistical significance was considered with p < 0.05. Results: 560 subjects were studied in 4 groups. The average age 49 ± 11 years old. The highest frequency of diabetes mellitus (34.29%), arterial hypertension (50%) and hiperlipidemia (36.43%) was in the obesity group, and being snoring (73.57%) in morbid obesity. There were differences from the normal group versus. morbid obesity: PaCO2 31.37 ± 2.08 versus. 38.14 ± 5.10 mmHg; PaO2 68.28 ± 6.06 versus. 59.86 ± 9.28 mmHg and SaO2 93.51 ± 1.93 versus. 89.71 ± 5.37%, all with p = 0.0001. The IMC-PaCO2 correlation: 0.497, and IMC-PaO2: −0.365, p = 0.0001 respectively. Conclusions: At the altitude of Mexico City and body mass index > 30 kg/m2 the variables related to gas exchange and simple spirometry begin to deteriorate; are evident with BMI > 40 kg/m2.

Deterioro del intercambio gaseoso en sujetos con incremento del índice de masa corporal a una altitud de 2, 240 metros sobre el nivel del mar / Deterioration of gas exchange in subjects with an increase in body mass index at an altitude of 2, 240 meters above sea level

Resumen Introducción: Las alteraciones del intercambio gaseoso se han reconocido en la obesidad mórbida; sin embargo, no se conoce su comportamiento conforme se incrementa el índice de masa corporal. Objetivo: Conocer el comportamiento del intercambio gaseoso a la altura de la Ciudad de México en el desarrollo de obesidad mórbida. Métodos: Mediante un diseño transversal analítico se estudió a sujetos pareados por género y edad de cuatro grupos diferentes de índice de masa corporal (kg/m2): normal (18.5-24.9), sobrepeso (25-29.9), obesidad (30-39.9) y obesidad mórbida (≥ 40). Se obtuvieron sus antecedentes patológicos y demográficos, variables de gasometría arterial y espirometría simple. Las variables se determinaron de acuerdo con las características de la muestra; las diferencias entre grupos se realizaron mediante Anova de una vía con ajuste de Bonferroni, así como la correlación de Pearson para las variables relacionadas. Una p < 0.05 se consideró con significación estadística. Resultados: Se estudió a 560 pacientes en cuatro grupos. La edad promedio fue de 49 ± 11 años. La mayor frecuencia de diabetes mellitus (34.29%), hipertensión arterial (50%) e hiperlipidemia (36.43%) se registró en el grupo de obesidad, y la de roncador (73.57%) en la obesidad mórbida. Se identificaron diferencias desde el grupo normal respecto de la obesidad mórbida: PaCO2 31.37 ± 2.08 vs. 38.14 ± 5.10 mmHg; PaO2 68.28 ± 6.06 vs. 59.86 ± 9.28 mmHg y SaO2 93.51 ± 1.93 vs. 89.71 ± 5.37%, todas con p = 0.0001. Correlación IMC-PaCO2: 0.497, e IMC-PaO2: -0.365, p = 0.0001, respectivamente. Conclusiones: A la altitud de la Ciudad de México y con índice de masa corporal > 30 kg/m2, las variables relacionadas con el intercambio gaseoso y espirometría simple comienzan a deteriorarse; son evidentes con IMC > 40 kg/m2.

Abstract Introduction: Alterations of gas exchange have been recognized in morbid obesity, however, it is not known how their behavior would be as the body mass index increases. Objective: To know the behavior of gas exchange at the level of Mexico City in the development of morbid obesity. Methods: Through analytical design, subjects matched by gender and age were studied from four different groups of body mass index (kg/m2), normal (18.5-24.9), overweight (25-29.9), obesity (30-39.9) and morbid obesity (≥ 40). Their pathological and demographic antecedents, arterial blood gas and simple spirometry variables were obtained. The variables were shown according to their sample characteristic. The differences between groups were made using one way Anova with Bonferroni adjustment, as well as Pearson’s correlation for the related variables. Statistical significance was considered with p < 0.05. Results: 560 subjects were studied in 4 groups. The average age 49 ± 11 years old. The highest frequency of diabetes mellitus (34.29%), arterial hypertension (50%) and hiperlipidemia (36.43%) was in the obesity group, and being snoring (73.57%) in morbid obesity. There were differences from the normal group versus. morbid obesity: PaCO2 31.37 ± 2.08 versus. 38.14 ± 5.10 mmHg; PaO2 68.28 ± 6.06 versus. 59.86 ± 9.28 mmHg and SaO2 93.51 ± 1.93 versus. 89.71 ± 5.37%, all with p = 0.0001. The IMC-PaCO2 correlation: 0.497, and IMC-PaO2: −0.365, p = 0.0001 respectively. Conclusions: At the altitude of Mexico City and body mass index > 30 kg/m2 the variables related to gas exchange and simple spirometry begin to deteriorate; are evident with BMI > 40 kg/m2.

"I Matter, I Learn, I Decide": An Impact Evaluation on Knowledge, Attitudes, and Rights to Prevent Adolescent Pregnancy.

Adolescent pregnancy is considered a priority public health issue because of its implications in the lives of young mothers, their children, and the well-being of the general population. In this paper, we describe an intervention targeting adolescents (aged 11-19 years old) in a rural context and estimate its impact on key outcomes relevant to early pregnancy prevention: knowledge and self-efficacy concerning sexual and reproductive health, knowledge of sexual and reproductive rights, and attitudes toward gender roles. Our study used a quasi-experimental design comprising 747 adolescents. Three difference-in-differences models (raw, adjusted, and by exposure level) with fixed effects estimated the changes in all outcome measures. Our results showed that the intervention community had a significant improvement in all outcomes, and this improvement was larger in those who received the highest-exposure level of intervention compared to a control community. Our study provides evidence that a community-based intervention, founded on comprehensive sexual education, is a promising approach to improve key outcomes related to early pregnancy in rural contexts. Further research should be undertaken to test how similar strategies focusing on multi-layer early pregnancy determinants work on other sub-groups of vulnerable adolescents, such as school dropouts or those living in disadvantaged circumstances.

Perfil epidemiológico, clínico y funcionalidad alcanzada de la población con lesión medular traumática asistida en el Servicio de Rehabilitación y Medicina Física en el Hospital Universitario / Clinical and epidemiological profile and functionality achieved in patients with traumatic spinal cord injury assisted at the Rehabilitation and Physical Medicine Service at the University Hospital / Perfil epidemiológico, clínico e funcional alcançado da população com lesão medular traumática atendida no Serviço de Reabilitação e Medicina Física do Hospital Universitário

Resumen: La lesión medular traumática puede afectar todas las funciones de la médula espinal determinando limitaciones de la actividad y restricciones en la participación. Conocer el perfil epidemiológico propio es imperativo para planificar la asistencia, los recursos y actuar en prevención. En la Cátedra de Rehabilitación hay una larga trayectoria de asistencia en equipo interdisciplinario a personas con lesión medular traumática; a partir de 1987 se documentaron datos que fueron analizados y presentados en 2004 en el Congreso Nacional de Neurología. Objetivo: describir las características sociodemográficas, clínicas, funcionales y terapéuticas de nuestra población. Método: se realizó un estudio longitudinal, retrospectivo, descriptivo y analítico de toda la población asistida durante el período 2004-2017. Resultados: n=70, 86% masculino, de 40±18 años. Las causas fueron: precipitación 36,4%, tránsito 31,8% y violencia 28,8%; el nivel cervical 57%, dorsal 40% y lumbar 3%. La escala de la American Spinal Injury Association (ASIA) de inicio fue 36,2% A, 13,8% B, 22,4% C y 5,2% D. ASIA final, 29,0% A, 3,2% B, 27,4% C, 25,8% D. El 45% logró independencia en actividades básicas de la vida diaria, el 60% independencia en transferencias y el 45% en marcha. Conclusiones: disminuyó el número de nuevos casos en los últimos cuatro años y cambió el perfil etiológico. Predominaron los hombres jóvenes, lesiones por precipitación, tránsito y violencia, las cuadriparesias incompletas, seguido de paraplejias completas e incompletas. Las complicaciones más frecuentes fueron nefrourológicas y escaras. De la funcionalidad alcanzada, la mayoría de los pacientes fueron dependientes en actividades de vida diaria, transfirieron en forma independiente y no lograron marcha.

Summary: Traumatic spinal cord injury may affect all functionalities of the spinal cord, what determines limitation in activity and restrictions in participation. Learning about its epidemiological profile is of the essence to plan healthcare, resources and preventive actions. The Rehabilitation Chair has a long history in providing healthcare to people with traumatic spinal cord injury in multidisciplinary teams. Data has been recorded since 1987, which information was analysed and presented at the National Neurology Conference in 2004. Objective: to describe the socio-demographic, clinical, functional and therapeutic characteristics of our population. Method: we conducted a longitudinal, retrospective, descriptive and analytical study of the entire population assisted between 2004 and 2017. Results: n=70, 86% male, 40±18 years old. The following causes were found: falls 36.4%, road accidents 31.8% and violence 28.8%; cervical level 57%, dorsal spine 40% and lumbar spine 3%. Initial ASIA impairment scale was 36.2% A, 13.8% B, 22.4% C and 5.2% D. Final ASIA impairment scale was 29.0% A, 3.2% B, 27.4% C, 25.8% D. 45% achieved independence in everyday basic activities, 60% transfer independence and 45% independent gait. Conclusions: the number of new cases decreased in the last 4 years and the etiological profile changed. Young men prevailed, lesions caused by falls, road accidents and violence were the most frequent, incomplete quadriparesis, followed by complete and incomplete paraplegia. The most frequent complications were nephro-urological and pressure sores. As to the functionality achieved, most patients were dependent in every day life activities, they could transfer independently and could not achieve independent gait.

Resumo A lesão medular traumática pode afetar todas as funções da medula espinhal, determinando limitações de atividade e restrições de participação. Conhecer o perfil epidemiológico da população atendida é imprescindível para planejar cuidados, recursos e atuar na prevenção. A Cátedra de Reabilitação (CRMF) tem uma longa trajetória de assistência com equipe interdisciplinar às pessoas com Lesão Medular Traumática; a partir de 1987, foram registrados dados que foram analisados e apresentados em 2004 no Congresso Nacional de Neurologia. Objetivo: descrever as características sociodemográficas, clínicas, funcionais e terapêuticas da população atendida pela equipe de reabilitação da CRMF no período 2004-2007. Métodos: foi realizado um estudo longitudinal, retrospectivo, descritivo e analítico de toda a população assistida no período de 2004-2017. Resultados: 70 pacientes foram atendidos sendo 86% de sexo masculino, com idade 40 ± 18 anos. As causas foram: precipitação 36,4%, trânsito 31,8% e violência 28,8%; o nível cervical 57%, dorsal 40% e lombar 3%. A Escala da American Spinal Injury Association (ASIA) inicial era 36,2% A, 13,8% B, 22,4% C e 5,2% D. ASIA final, 29,0% A, 3,2% B, 27,4% C, 25,8% D. 45% alcançaram independência nas atividades básicas de vida diárias, 60% independência nas transferências e 45% na marcha. Conclusões: o número de casos novos diminuiu nos últimos 4 anos e o perfil etiológico mudou. Predominou o sexo masculino, as lesões por precipitação, trânsito e violência, as quadriparesias incompletas, seguidas de paraplegias completas e incompletas. As complicações mais frequentes foram nefrourológicas e escaras. Em relação à funcionalidade alcançada, a maioria dos pacientes era dependente nas atividades da vida diária, movia-se de forma independente e não conseguiram autonomia na marcha.

[Prevalence and associated factors of moderncontraceptive methods use among adolescents,2012 and 2018]. / Prevalencias y factores asociados con el uso de métodos anticonceptivos modernos en adolescentes, 2012 y 2018.

OBJECTIVE: To analyze the prevalence of modern contracep-tive methods (CM) use in adolescents aged 12 to 19 years in 2012 and 2018-19, and the factors associated with consistent use of modern CM. MATERIALS AND METHODS: Using the Health and Nutrition National Surveys 2012 and 2018-19 we calculated the outcome variables: long-acting reversible con-traceptives (LARC) use, dual protection and consistent use of CM. We estimated prevalence by sex and adjusted logistic models with consistent use (which is understood as CM use in the first and last sexual relationship) as a dependent variable. RESULTS: LARC use in last intercourse increased between surveys (4.1 to 6.3%). For women, being older, not having been pregnant, and school attendance increased the likelihood of consistent use. For men, school attendance increases the likelihood while cohabiting, early sexual initiation and having smoked more than 100 cigarettes reduces it. CONCLUSIONS: It is necessary to promote access and consistent use of MC, based on respect for sexual and reproductive rights.

OBJETIVO: Analizar la prevalencia de uso de métodos anticonceptivos (MAC) modernos en adolescentes de 12 a19 años en 2012 y 2018-19, y factores asociados con su uso consistente. MATERIAL Y MÉTODOS: A partir de las Encuestas Nacionales de Salud y Nutrición 2012 y 2018-19, se construyeron variables de interés: uso de anticonceptivos reversibles de acción prolongada (ARAP), protección dual y uso consistente de MAC. Se calcularon prevalencias y modelos logísticos para uso consistente de MAC. RESULTADOS: El uso de ARAP en la última relación se incrementó entre encuestas (4.1 a 6.3%). Tener mayor edad, no embarazo y asistencia escolar incrementaron la posibilidad de uso consistente en mujeres; en hombres, la asistencia escolar la incrementó, y vivir en unión, inicio temprano de vida sexual y consumir >100 cigarrillos la disminuyeron. CONCLUSIONES: Es necesario fomentar el acceso y uso de MAC de manera consistente, basado en el respeto a los derechos sexuales y reproductivos.

Lot quality assurance sampling: Information provided to female users of contraceptive methods regarding side effects.

Women need to receive accurate information on the proper use of contraceptive methods (CM). The objective of our analysis was to evaluate the quality of CM counseling in health institutions of the public sector using the Lot Quality Assurance Sampling (LQAS) technique. We specifically analyzed whether health-service providers informed CM users of all the side effects they might experience, as specified under the Mexican health-care regulations. Our results demonstrated that, among the four CM analyzed -the intrauterine device, hormonal injection, condom and subdermal implant- only the users of the subdermal implant received complete information on side effects. Our findings thus indicate that the quality of family planning services in the institutions analyzed is deficient. We recommend that service providers be regularly trained in order to improve their performance and that LQAS methodology be adopted as an effective means of regularly monitoring the quality of health services in Mexico.