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1.
An Med Interna ; 23(7): 321-5, 2006 Jul.
Article in Spanish | MEDLINE | ID: mdl-17067231

ABSTRACT

OBJECTIVE: We studied the epidemiological characteristic of tuberculosis in Lorca area, drug resistant and the effect of the immigration population (Ecuador) in this area. PATIENTS AND METHODS: A retrospective study for six years ago (1999, January to 2004, December) was realized. Epidemiological data, initial diagnostic probability, mycobacteria stain and cultive, drug resistance, treatment response, and epidemiological differences between immigrants and spain population were compared. RESULTS: Within 158 cases registered, 41.7 percent were immigrants with less than one year in Spain, the most part Ecuador population. We observed that extrapulmonar tuberculosis was lower initial diagnostic probability than pleural disease as well too haemoptisis, pleural pain and weight loss. It was identified positive micobacterial stain in 35.4 percent of respiratory samples. It was successfully results in 74 percent of cases and 13.9 percent of patients were lost, this result was frequently registered in immigrants, The isoniazide resistant in patients with not previous treatment was 5.3 percent and it was 9.5 percent in immigrants and 10.8 percent in Ecuador population. CONCLUSION: It is necessary improve: the diagnostic of extrapulmonar tuberculosis and avoid loss patient by programs of capture and then the successfully treatments raise. The isoniazide resistant in this area suggest that we must use initial four drug than tree and this manner not raise the drug resistant in the area.


Subject(s)
Mycobacterium tuberculosis/isolation & purification , Tuberculosis, Pulmonary/epidemiology , Adult , Antitubercular Agents/therapeutic use , Emigration and Immigration , Female , Humans , Incidence , Male , Mycobacterium tuberculosis/drug effects , Retrospective Studies , Risk Factors , Spain/epidemiology , Tuberculosis, Multidrug-Resistant/diagnosis , Tuberculosis, Multidrug-Resistant/drug therapy , Tuberculosis, Multidrug-Resistant/epidemiology , Tuberculosis, Pulmonary/diagnosis , Tuberculosis, Pulmonary/drug therapy
2.
An. med. interna (Madr., 1983) ; 23(7): 321-325, jul. 2006. ilus, tab
Article in Es | IBECS | ID: ibc-048144

ABSTRACT

Objetivo: analizar las características epidemiológicas de los casos de tuberculosis del área de salud de la comarca de Lorca, su resistencia a fármacos y el impacto de la población inmigrante mayoritaria (Ecuador) en la misma. Pacientes y métodos: estudio longitudinal, retrospectivo de 6 años de duración (de enero de 1999 a diciembre 2004). Se recogieron datos epidemiológicos de cada caso, probabilidad diagnóstica inicial, tinciones diagnósticas, aislamientos, resistencia a fármacos, respuesta al tratamiento, así como, las diferencias epidemiológicas existentes entre inmigrantes y autóctonos. Resultados: Se identificaron 158 casos, 41,7% eran inmigrantes con menos de 1 año de estancia en nuestro país, mayoritariamente procedentes de Ecuador. Observamos que la tuberculosis extrapulmonar para el clínico tenía una probabilidad diagnóstica baja, mientras que la pleural era alta, junto a síntomas como hemoptisis, dolor pleurítico y constitucionales. En 35,4% de los casos se idéntifico germen por tinción en muestras respiratorias. Se obtuvo un 74% de resultados satisfactorios por el tratamiento y 13,9% de abandono asociado frecuentemente con la inmigración. La resistencia a isoniazida en no tratados fue del 5,3% en el área, 9,5% en el caso de inmigrantes y 10,8% en los oriúndos de Ecuador. Conclusión: Se debe mejorar en: la detección de los casos extrapulmonares, evitar el abandono con la captación de los enfermos y la curación de enfermedad. Las resistencias a isoniazida en nuestra área sugiere adaptarse a tratamientos de inicio con cuatro fármacos y no a tres para evitar incremento de resistencias en nuestra área de salud


Objective: We studied the epidemiological characteristic of tuberculosis in Lorca area, drug resistant and the effect of the immigration population (Ecuador) in this area. Patients and methods: A retrospective study for six years ago (1999, January to 2004, December) was realized. Epidemiological data, initial diagnostic probability, mycobacteria stain and cultive, drug resistance, treatment response, and epidemiological differences between immigrants and spain population were compared. Results: Within 158 cases registred, 41.7 percent were immigrants with less than one year in Spain, the most part Ecuador population. We observed that extrapulmonar tuberculosis was lower initial diagnostic probability than pleural disease as well too haemoptisis, pleural pain and weight loss. It was identified positive micobacterial stain in 35.4 percent of respiratory samples. It was succesfully results in 74 percent of cases and 13.9 percent of patients were lost, this result was frecuently registred in immigrants, The isoniazide resistant in patients with not previous treatment was 5.3 percent and it was 9.5 percent in immigrants and 10.8 percent in Ecuador population. Conclusion: It is necessary improve: the diagnostic of extrapulmonar tuberculosis and avoid loss patient by programs of capture and then the succesfully treatments raise. The isoniazide resistant in this area suggest that we must use initial four drug than tree and this manner not raise the drug resistant in the area


Subject(s)
Humans , Tuberculosis/epidemiology , Spain/epidemiology , Ecuador/epidemiology , Emigration and Immigration/statistics & numerical data , Risk Factors , Longitudinal Studies , Disease Notification/statistics & numerical data , Transients and Migrants/statistics & numerical data
3.
Emergencias (St. Vicenç dels Horts) ; 18(2): 87-93, abr. 2006. tab
Article in Es | IBECS | ID: ibc-044447

ABSTRACT

Objetivos: Conocer las características etiológicas de los pacientes ingresados en la sección de Neumología por hemoptisis y su distribución en nuestro medio con relación a otras series. Métodos: Se realizó un estudio retrospectivo revisando las historias clínicas de los pacientes diagnosticados de hemoptisis en el servicio de neumología del Hospital Universitario Virgen de la Arrixaca, durante el año 2002. Resultados: Se estudiaron 70 pacientes, de los cuales 15 (21,4%) eran mujeres, y 55 hombres (78,5%). La edad media fue de 58,7 años. Fumadores y exfumadores de menos de 10 años constituyeron el 48,6%, exfumadores de más de 10 años 17,14%, no fumadores 35,7%. Los diagnósticos obtenidos fueron: bronquiectasias 24,3%, cáncer de pulmón 20%, infecciones respiratorias 12,8%, criptogenéticas 11,4%, bronquitis crónica 8,5%, TBC activa 7,1%, lesiones residuales por TBC 4,3%; abscesos 2,8%; sobredosificación por dicumarínicos 2,8%, malformaciones vasculares 2,8%, aspergiloma 1,4% fibrosis pulmonar 1,4%. Por rangos de edad encontramos diferencias, presentándose como primera causa en pacientes en mayores de 80 años y entre 50-59 años el cáncer de pulmón, entre 60 y 79 años las bronquiectasias y en los menores de 50 las infecciones respiratorias. El cáncer, también supone la primera causa en los pacientes fumadores y exfumadores desde hace menos de 10 años. Entre los exfumadores de más de 10 años destacan las bronquiectasias y en los no fumadores las infecciones respiratorias. En cuanto al diagnóstico la TC es diagnóstica en el 61,1%, la RX tórax en el 44,4% y la broncoscopia en el 11,1%; aunque localiza el sangrado en hasta el 47,2%. Conclusiones: La causa más frecuente de hemoptisis en nuestro medio es la secundaria a bronquiectasias, seguidas del cáncer de pulmón y de las infecciones respiratorias (AU)


Objectives: The aim of this review is know the etiology of hemoptysis in pneumology´s patients and its distribution in ours area compared with others series. Methods: We have made a restrospective and descriptive study about the clinical records of patients with diagnosis of hemoptysis in pneumology section from our hospital during the year 2002. Results: We have studied 70 clinical reports: 15 (21.4%) were women and 55 men (78.5%). The mean age was 58.7 years. Smoker and ex-smoker of less than 10 years were 48.6%, ex-smoker of more than10 years were 17.14% and non-smoker were 35.7%. The result included the following diagnosis: bronchiectasis 24.3%, lung cancer 20%, respiratory infecctions 12.8%, criptogenic 11.4%, chronic bronchitis 8.5%, active TBC 7.1%, residual lesions of TBC 4.3% abscess 2.8%, overdosis of anticoagulants 2.8%, vascular malformation 2.8%, aspergilloma 1.4% pulmonary fibrosis 1.4%. For age intervals we found differences: In the intervals 81-90 years and 51-60 years the main cause were lung cancer, between 61-80 years were bronchyectasis and <50 years respiratory infecitons. The lung cancer were also the most important cause the hemoptysis among the smokers and ex-smokers of less than 10 years. In non-smokers were the bronchiectasis. Conclusion: Bronchiectasis, lung cancer, and respiratory infections are the most common causes of hemoptysis in our area. In the same way that others series, we have found a important descent of impact of tuberculosis, but not in the bronchiectasis, as in others mediterraneans countries, where in their series is the main cause of hemoptysis (AU)


Subject(s)
Adult , Humans , Hemoptysis/complications , Hemoptysis/diagnosis , Hemoptysis/pathology , Bronchiectasis/complications , Bronchiectasis/diagnosis , Bronchiectasis/pathology , Lung Neoplasms/etiology , Lung Neoplasms/physiopathology , Hemoptysis/etiology , Bronchiectasis/etiology , Radiography, Thoracic , Risk Factors , Prevalence , Diagnosis, Differential
4.
Arch Bronconeumol ; 38(5): 246-8, 2002 May.
Article in Spanish | MEDLINE | ID: mdl-12028933

ABSTRACT

Liver abscess due to Mycobacterium tuberculosis associated with pulmonary tuberculosis is a rare diagnosis, particularly in patients without AIDS. We report the case of a male immigrant with no HIV infection who developed a tuberculous liver abscess and pulmonary tuberculosis simultaneously. Ziehl-Neelsen stain, PCR and Löwenstein-Jensen culture of material sampled from the abscess established the microbiological diagnosis. The patient's course was good, with disappearance of symptoms and the abscess after tuberculostatic treatment and drainage of the abscess with monitoring by computed tomography.


Subject(s)
Liver Abscess/complications , Tuberculosis, Hepatic/complications , Tuberculosis, Pulmonary/complications , Adult , Antitubercular Agents/therapeutic use , Drainage , Follow-Up Studies , Humans , Liver Abscess/diagnosis , Liver Abscess/diagnostic imaging , Liver Abscess/drug therapy , Liver Abscess/surgery , Male , Mycobacterium tuberculosis/isolation & purification , Polymerase Chain Reaction , Radiography, Thoracic , Time Factors , Tomography, X-Ray Computed , Tuberculosis, Hepatic/diagnosis , Tuberculosis, Hepatic/diagnostic imaging , Tuberculosis, Hepatic/drug therapy , Tuberculosis, Pulmonary/diagnostic imaging , Tuberculosis, Pulmonary/drug therapy
5.
Arch. bronconeumol. (Ed. impr.) ; 38(5): 246-248, mayo 2002.
Article in Es | IBECS | ID: ibc-12669

ABSTRACT

El absceso hepático por Mycobacterium tuberculosis asociado a una tuberculosis pulmonar es un diagnóstico poco frecuente, e incluso aún más raro es encontrarlo en pacientes sin el síndrome de la inmunodeficiencia adquirida (sida).Presentamos el caso de un paciente inmigrante con serología negativa para el virus de la inmunodeficiencia humana (VIH) que presentó simultáneamente un absceso hepático tuberculoso y una tuberculosis pulmonar. La tinción de Ziehl-Neelsen, la PCR y el cultivo en Löwenstein-Jensen del material extraído del absceso permitieron establecer el diagnóstico microbiológico del mismo. La evolución fue buena, con desaparición de los síntomas y del absceso, tras tratamiento tuberculostático y drenaje del absceso bajo control mediante tomografía computarizada (TC) (AU)


Subject(s)
Adult , Male , Humans , Radiography, Thoracic , Tuberculosis, Hepatic , Time Factors , Tomography, X-Ray Computed , Tuberculosis, Pulmonary , Polymerase Chain Reaction , Mycobacterium tuberculosis , Antitubercular Agents , Drainage , Liver Abscess , Follow-Up Studies
6.
Rev. esp. quimioter ; 13(4): 379-383, dic. 2000.
Article in Es | IBECS | ID: ibc-12866

ABSTRACT

A pesar de los avances en terapéutica, los pacientes con EPOC requieren frecuentes hospitalizaciones debido a sus exacerbaciones. De forma prospectiva y aleatorizada hemos estudiado dos grupos de pacientes con EPOC. El grupo de estudio (54 pacientes) recibió de forma profiláctica azitromicina (500 mg/día) durante tres días cada 21 días durante todo el periodo invernal, y el grupo control (40 pacientes) no recibió el tratamiento profiláctico. Hemos encontrado una reducción significativa en el número de exacerbaciones (187) y de ingresos hospitalarios (22) en el grupo que recibió azitromicina en comparación con el grupo control (249 y 45, respectivamente). Los ciclos de tratamiento profiláctico corto e intermitente con azitromicina representan una buena opción en los pacientes con EPOC grave y evolucionada, mejorando su coste sanitario y social (AU)


Subject(s)
Aged , Male , Female , Humans , Statistics , Antibiotic Prophylaxis , Azithromycin , Prospective Studies , Bacterial Infections , Anti-Bacterial Agents , Hospitalization , Lung Diseases, Obstructive
7.
Arch Bronconeumol ; 36(8): 485-7, 2000 Sep.
Article in Spanish | MEDLINE | ID: mdl-11004990

ABSTRACT

Exogenous lipoid pneumonia is a rare disease which is often underdiagnosed. Exogenous lipoid pneumonia has traditionally been considered a chronic process secondary to continued aspiration or inhalation of fatty substances. In its acute form exogenous lipoid pneumonia sometimes coincides with accidental massive aspiration of lipidic material, as has been traditionally described for fire eaters. We review the literature and report a case of acute lipoid pneumonia secondary to accidental aspiration of vaseline used to place a nasogastric tube, which had been inserted for gastric lavage after a suicide attempt by flurazepam ingestion.


Subject(s)
Emollients/adverse effects , Intubation, Gastrointestinal , Petrolatum/adverse effects , Pneumonia, Lipid/chemically induced , Acute Disease , Adult , Female , Humans
8.
Arch. bronconeumol. (Ed. impr.) ; 36(8): 485-487, sept. 2000.
Article in Es | IBECS | ID: ibc-4197

ABSTRACT

La neumonía lipoidea exógena es una entidad poco frecuente y a menudo infradiagnosticada. Clásicamente, se ha considerado un proceso crónico secundario a la aspiración o inhalación continuada de sustancias grasas. En ocasiones, se puede observar una forma aguda coincidiendo con aspiraciones accidentales masivas de material lipídico descrita tradicionalmente en "comedores de fuego"1,2. Revisamos la bibliografía y presentamos un caso de neumonía lipoidea aguda secundaria a la aspiración accidental de vaselina utilizada en la colocación de una sonda nasogástrica para un lavado gástrico, tras intento de autólisis mediante la ingesta de flurazepam. (AU)


Subject(s)
Adult , Female , Humans , Intubation, Gastrointestinal , Petrolatum , Pneumonia, Lipid , Acute Disease , Emollients
9.
Rev Esp Quimioter ; 13(4): 379-83, 2000 Dec.
Article in Spanish | MEDLINE | ID: mdl-11498704

ABSTRACT

Despite the advances in therapy, chronic obstructive pulmonary disease (COPD) requires frequent hospital admissions due to acute exacerbations. We carried out a prospective randomized study of two groups of patients with COPD, one (n = 54) treated with azithromycin (500 mg/day) for three days every 21 days during the winter months, and a control group (n = 40) without treatment. A statistically significant reduction in the number of acute infectious episodes (187) and hospital admissions (22) was observed in the treated group versus the control group (249 and 45, respectively). A short prophylactic treatment course with azithromycin is a good alternative in the management of patients with severe, advanced COPD, and could lead to an improvement in social and healthcare costs


Subject(s)
Anti-Bacterial Agents/therapeutic use , Antibiotic Prophylaxis/methods , Azithromycin/therapeutic use , Lung Diseases, Obstructive/drug therapy , Aged , Bacterial Infections/complications , Bacterial Infections/drug therapy , Female , Hospitalization , Humans , Lung Diseases, Obstructive/microbiology , Male , Prospective Studies , Statistics as Topic
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