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1.
Adv Exp Med Biol ; 1318: 911-921, 2021.
Article in English | MEDLINE | ID: mdl-33973219

ABSTRACT

In the COVID-19 era, while we are encouraged to be physically far away from each other, social and scientific networking is needed more than ever. The dire consequences of social distancing can be diminished by social networking. Social media, a quintessential component of social networking, facilitates the dissemination of reliable information and fighting against misinformation by health authorities. Distance learning, telemedicine, and telehealth are among the most prominent applications of networking during this pandemic. Additionally, the COVID-19 pandemic highlights the importance of collaborative scientific efforts. In this chapter, we summarize the advantages of harnessing both social and scientific networking in minimizing the harms of this pandemic. We also discuss the extra collaborative measures we can take in our fight against COVID-19, particularly in the scientific field.


Subject(s)
COVID-19 , Social Media , Humans , Pandemics , Physical Distancing , SARS-CoV-2 , Socialization
3.
Biomed Pharmacother ; 131: 110738, 2020 Nov.
Article in English | MEDLINE | ID: mdl-33152914

ABSTRACT

The novel coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can be considered as the most important current global issue, as it has caused the novel coronavirus disease (COVID-19) pandemic, which has resulted in high mortality and morbidity rates all around the world. Although scientists are trying to discover novel therapies and develop and evaluate various previous treatments, at the time of writing this paper, there was no definite therapy and vaccine for COVID-19. So, as COVID-19 has called ideas for treatment, controlling, and diagnosis, we discussed the application of Clustered Regularly Interspaced Short Palindromic Repeats/Cas13 (CRISPR/Cas13) as a treatment of COVID-19, which received less attention compared with other potential therapeutic options.


Subject(s)
Betacoronavirus/genetics , CRISPR-Cas Systems , Coronavirus Infections/therapy , Gene Editing , Genetic Therapy/methods , Pneumonia, Viral/therapy , RNA, Viral/genetics , Betacoronavirus/drug effects , COVID-19 , CRISPR-Associated Proteins/pharmacology , Conserved Sequence , Coronavirus Infections/drug therapy , Coronavirus Infections/genetics , Genome, Viral , Humans , Pandemics , Pneumonia, Viral/genetics , RNA, Guide, Kinetoplastida/genetics , RNA, Viral/antagonists & inhibitors , SARS-CoV-2 , COVID-19 Drug Treatment
4.
J Med Virol ; 92(10): 1864-1874, 2020 10.
Article in English | MEDLINE | ID: mdl-32492197

ABSTRACT

Nowadays, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which caused novel coronavirus disease (COVID-19) pandemic, is the worldwide challenge. The virus is highly contagious, and clinical consequences were very divers. It is estimated that if no effective action is taken, COVID-19 could plague 90% of the world's population and kill over 40 million people. So, it is essential to understand the virus pathogenicity and follow the preventive methods to control the high morbidity and mortality rates. Meanwhile our current knowledge of COVID-19 is still limited, despite hard efforts of scientists and clinicians during last few months. In this review article, we have collected the latest data about characteristics, pathogenesis, clinical manifestations, and diagnostic methods of SARS-CoV-2.


Subject(s)
COVID-19/physiopathology , SARS-CoV-2/pathogenicity , Adaptive Immunity , Angiotensin-Converting Enzyme 2 , COVID-19/mortality , Cytokine Release Syndrome/virology , Humans , Immunity, Innate , Risk Factors
5.
Clin Chim Acta ; 508: 254-266, 2020 Sep.
Article in English | MEDLINE | ID: mdl-32474009

ABSTRACT

The novel coronavirus disease (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), remains a global challenge. Despite intense research efforts worldwide, an effective vaccine and viable treatment options have eluded investigators. Therefore, infection prevention, early viral detection and identification of successful treatment protocols provide the best approach in controlling disease spread. In this review, current therapeutic options, preventive methods and transmission routes of COVID-19 are discussed.


Subject(s)
Betacoronavirus/drug effects , COVID-19/epidemiology , COVID-19/therapy , Coronavirus Infections/epidemiology , Coronavirus Infections/therapy , Pandemics , Pneumonia, Viral/epidemiology , Pneumonia, Viral/therapy , Adrenal Cortex Hormones/therapeutic use , Antiviral Agents/therapeutic use , Betacoronavirus/pathogenicity , COVID-19/prevention & control , COVID-19/transmission , COVID-19 Vaccines , Clinical Trials as Topic , Coronavirus Infections/prevention & control , Coronavirus Infections/transmission , Drug Repositioning , Humans , Immunization, Passive/methods , Immunologic Factors/therapeutic use , Molecular Targeted Therapy/methods , Pandemics/prevention & control , Personal Protective Equipment , Physical Distancing , Pneumonia, Viral/prevention & control , Pneumonia, Viral/transmission , SARS-CoV-2 , Viral Vaccines/biosynthesis , COVID-19 Serotherapy
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