1.
J Biol Regul Homeost Agents
; 33(2): 457-460, 2019.
Article
in English
| MEDLINE
| ID: mdl-30916512
ABSTRACT
Keratoconus (KC) is a multifactorial, progressive, degenerative corneal disorder with an incidence of approximately 1 in 2,000 subjects.
Subject(s)
Keratoconus/enzymology , Superoxide Dismutase-1/metabolism , Transcription Factors/metabolism , Humans , Keratoconus/genetics , Superoxide Dismutase-1/genetics , Transcription Factors/genetics
2.
J Biol Regul Homeost Agents
; 33(6): 1879-1884, 2019.
Article
in English
| MEDLINE
| ID: mdl-31970969
3.
J Biol Regul Homeost Agents
; 32(6): 1515-1518, 2018.
Article
in English
| MEDLINE
| ID: mdl-30574758
ABSTRACT
Keratoconus (KC) is a complex, genetically heterogeneous, multifactorial degenerative corneal disorder, with incidence of approximately 1 per 2000 of the population. KC follows an autosomal recessive or dominant pattern of inheritance and is, apparently, associated with genes which interact with environmental, genetic and/or other factors. The present report focuses on the VSX1 gene, for which there is general agreement that it is involved in KC and other corneal pathologies, and critically details the evidence for its involvement in KC.