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The complete mitochondrial genome sequence and mutations of the lung cancer model inbred rat strain (Muridae; Rattus).
Zhou, Da-Ming; Zhu, Dan-Dan; Lu, Qing-Feng; Qiao, Wen-Bo; Zhuang, Yong-Zhi.
Mitochondrial DNA A DNA Mapp Seq Anal ; 27(2): 1260-1, 2016.
Article in English | MEDLINE | ID: mdl-25391029

ABSTRACT

We reported the complete mitochondrial genome sequencing of an important Lung cancer model inbred rat strain for the first time. The total length of the mitogenome was 16,312 bp. It harbored 13 protein-coding genes, 2 ribosomal RNA genes, 22 transfer RNA genes and 1 non-coding control region. The mutation sites were analyzed by comparing with the reference BN strain.


Subject(s)
DNA, Mitochondrial/genetics , Genome, Mitochondrial/genetics , Lung Neoplasms/genetics , Mitochondria/genetics , Rats, Inbred F344/genetics , Animals , Base Composition/genetics , Base Sequence , Codon, Initiator/genetics , Codon, Terminator/genetics , Disease Models, Animal , Female , Genome Size/genetics , Granuloma/chemically induced , Granuloma/pathology , Molecular Sequence Data , Polymerase Chain Reaction , RNA, Ribosomal/genetics , RNA, Transfer/genetics , Rats , Sequence Analysis, DNA , Silicon Dioxide/toxicity
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