Understanding percutaneous and subcutaneous central venous access devices.

Central venous access devices (CVADs) are commonly used in the inpatient and outpatient settings. Physician assistants must understand CVADs' indications, intended uses, functional lifespans, complications, and indications for removal. This article describes common CVADs used for administering medications, nutrition, and chemotherapy, and for hemodialysis and venous access for laboratory sampling.

Ventilator gas delivery wave form substantially impacts plateau pressure and peak-to-plateau pressure gradient determination.

BACKGROUND: To determine whether plateau pressure (Pplat) measurement is lowered and peak airway pressure (Pawpeak)-to-Plat gradient is increased by measurement on a decelerating compared with square gas delivery wave form. METHODS: Prospective before and after study of mechanically ventilated injured and critically ill patients in an adult surgical intensive care unit. Pplat, Pawpeak, and Pawpeak-to-Pplat gradient were measured on decelerating and square gas delivery wave forms. RESULTS: Pplat and other routine ventilator parameters were measured in 82 (47 trauma, 35 emergency general surgery) consecutive convenience sampled adult intensive care unit patients on decelerating and then square gas delivery wave forms. Peak gas flow was fixed at 40 L/min; all other parameters (rate, tidal volume, positive end-expiratory pressure) were held constant. All patients were managed on assist control volume cycled ventilation using fentanyl and midazolam or propofol; no neuromuscular blockade was used. Patients with Pawpeak more than 35 cm H2O were excluded. Comparing decelerating with square gas delivery, mean Pawpeak was lower (25.1 ± 2.3 cm H2O vs. 33.1 ± 2.1 cm H2O; p < 0.0001) and mean Pplat was lower (21.3 ± 1.9 cm H2O vs. 24.8 ± 2.5 cm H2O; p < 0.0001), resulting in a decreased Pawpeak-to-Pplat gradient (3.8 ± 2.1 vs. 8.3 ± 2.3; p < 0.0001). CONCLUSION: Changing from a decelerating to a square gas delivery wave form significantly increases Pplat and Pawpeak, thereby increasing the Pawpeak-to-Pplat gradient. This increase may prompt unwarranted therapy aimed at reducing the gradient to its normal value of 4 cm H2O pressure or less. Conversely, patients with a high Pawpeak on a square wave form may benefit from transitioning to a decelerating wave form before changing ventilation parameters. LEVEL OF EVIDENCE: Diagnostic study, level III.

Bridging the gap between training and advanced practice provider critical care competency.

Given the meteoric rise in physician assistants and nurse practitioners in critical care units across the United States, identifying successful paradigms with which to train these clinicians is critical to help meet current and future demands. We describe an apprenticeship model of training that is deployable in any ICU including curriculum, didactic and procedural training, as well as 3- and 6-month benchmarks that embraces dedicated intensivist mentorship.

When the ICU is the operating room.

BACKGROUND: The surgical intensive care unit (SICU) is increasingly used as a surrogate operating room (OR). This study seeks to characterize a Level I trauma center's operative undertakings in the SICU versus OR for trauma and emergency general surgery patients. METHODS: Operative and ICU databases were queried for all operative procedures as a function of procedure type (CPT code) and location (OR, ICU) from August 2002 through June 2009. Mode of ventilation, type of anesthesia used, and adverse outcomes were recorded. Data were divided into 2002-2006 versus 2007-2009 because of MD staffing and service structure changes. Time frames were compared via Student's t-test or χ(2) as appropriate; significance for p < 0.05 (*) versus 2002-2006. RESULTS: Trauma service-admitted patient volume increased from 2002-2003 (n = 1,293) to 2006-2007 (n = 1,577) and again in 2008-2009 (n = 1,825). Emergency general surgery total operative cases increased from 2002-2003 (n = 246) to 2005-2006 (n = 468). Case volume further increased in 2006-2007 (n = 767*), 2007-2008 (n = 1,071*), and 2008-2009 (n = 875*) compared with 2002-2003 or 2005-2006. Relaparotomy and temporary abdominal closure procedures were significantly increased in 2007-2008 (n = 109*) and 2008-2009 (n = 128*) versus 2002-2006 (n = 6) and 2006-2007 (n = 10). ICU cases were 11.5% of total cases (OR + ICU) spanning 2002-2006 and significantly increased to 24.3%* in 2007-2008 and 36%* in 2008-2009. Advanced ventilation was used in 15% of ICU cases in 2002-2003 and significantly increased to 40% in 2006-2007 and 78%* in 2008-2009. Neuromuscular blockade was rare; most cases (93.9%) were performed under deep sedation. CONCLUSION: Our ICU is increasingly used for surgical procedures traditionally reserved for the OR. Advanced ventilation management may influence the choice of operative location. The ICU may be safely used as an operative location for the critically ill and injured. LEVEL OF EVIDENCE: Epidemiologic study, level III.

Abdominal compartment syndrome: risk factors, diagnosis, and current therapy.

Abdominal compartment syndrome's manifestations are difficult to definitively detect on physical examination alone. Therefore, objective criteria have been articulated that aid the bedside clinician in detecting intra-abdominal hypertension as well as the abdominal compartment syndrome to initiate prompt and potentially life-saving intervention. At-risk patient populations should be routinely monitored and tiered interventions should be undertaken as a team approach to management.