ABSTRACT
Oral squamous cell carcinoma (OSCC) is the most common malignant tumor of the head and neck with an extremely poor five-year survival rate of approximately 50 to 55%, despite significant advances in diagnostic and therapeutic procedures over the past three decades [...].
Subject(s)
Carcinogenesis , Mouth Neoplasms , Humans , Mouth Neoplasms/therapy , Mouth Neoplasms/etiology , Mouth Neoplasms/pathology , Carcinogenesis/pathology , Carcinoma, Squamous Cell/therapy , Carcinoma, Squamous Cell/etiology , Carcinoma, Squamous Cell/pathologyABSTRACT
BACKGROUND: Data from patients with post-ablative dural defects reconstructed using a free temporalis muscle fascia graft (FTFG) after resection of anterior or central skull base tumors were retrospectively analyzed. METHODS: The primary predictor and outcome variables were the reconstructive methods for dural repair and postoperative cerebrospinal fluid (CSF) leakage rate, respectively. RESULTS: Eighty patients were included, and 94 postoperative dural reconstructions were performed using FTFG. The postoperative CSF leakage rate was 3.19%. The postoperative CSF leakage rates did not significantly differ between open and endonasal endoscopic surgeries (1.92% vs. 4.88%; p > 0.05). In cases completed using the endonasal endoscopic approach, the postoperative CSF leakage rate was significantly associated with the intraoperative CSF leak flow (p < 0.05). CONCLUSIONS: Post-ablative dural defect reconstruction using FTFG resulted in low postoperative CSF leakage and complication rates comparable to those of free fascia lata graft from available literature.
Subject(s)
Cerebrospinal Fluid Leak , Dura Mater , Plastic Surgery Procedures , Skull Base Neoplasms , Temporal Muscle , Humans , Female , Male , Middle Aged , Retrospective Studies , Skull Base Neoplasms/surgery , Skull Base Neoplasms/pathology , Adult , Plastic Surgery Procedures/methods , Aged , Cerebrospinal Fluid Leak/etiology , Dura Mater/surgery , Fascia/transplantation , Postoperative Complications/epidemiology , Young Adult , Treatment Outcome , Cerebrospinal Fluid Rhinorrhea/etiology , Cerebrospinal Fluid Rhinorrhea/surgery , AdolescentABSTRACT
The presence of supernumerary tooth (SNT) in the nasal cavity is a rare condition with limited literature data. We report two cases with a history of nasal obstruction and difficulty breathing. In both cases, clinical and radiological examination confirmed intranasal SNT. Extractions were executed in general anesthesia using Rochester-Pean instruments transnasally. In addition, a literature review of intranasal SNT was performed. The database search retrieved a total number of 50 cases in time period from 1970 to 2020. Mean age of patients was 22.5 years. Most common symptoms were unilateral obstruction of breathing and headache. Surgical extraction of intranasal SNT is recommended to eliminate the symptoms.