1.
Org Lett
; 25(12): 2123-2128, 2023 Mar 31.
Article
in English
| MEDLINE
| ID: mdl-36943758
ABSTRACT
An alkyne-isocyanide [3 + 2] cycloaddition followed by a Boulton-Katritzky rearrangement and a ring expansion is demonstrated. Different from the typical Boulton-Katritzky rearrangement, which forms five-membered ring products, the rearrangement-ring expansion method provides a mild, efficient, and atom-economical access to fused 9-deazaguanine structures in high yields.