1.
Int J Surg Pathol
; 27(8): 888-892, 2019 Dec.
Article
in English
| MEDLINE
| ID: mdl-31405309
ABSTRACT
Human papillomavirus (HPV)-related multiphenotypic sinonasal carcinoma (HMSC), originally known as HPV-related carcinoma with adenoid cystic carcinoma-like features, is a recently described neoplasm that presents only in the sinonasal tract, displays features of both a surface-derived carcinoma and a salivary gland carcinoma, and is associated with high-risk HPV, specifically HPV type 33. Majority of the cases display high-grade histologic features, but HMSC paradoxically behaves in a relatively indolent fashion. Distinguishing HMSC from other histologic mimickers is essential as the management and prognosis are significantly different. In this article, we present a unique case of HMSC and review the literature.
Subject(s)
Carcinoma/diagnosis , Papillomaviridae/isolation & purification , Papillomavirus Infections/diagnosis , Paranasal Sinus Neoplasms/diagnosis , Carcinoma/pathology , Carcinoma/surgery , Carcinoma/virology , Endoscopy , Female , Humans , Middle Aged , Nasal Surgical Procedures , Papillomaviridae/pathogenicity , Papillomavirus Infections/pathology , Papillomavirus Infections/surgery , Papillomavirus Infections/virology , Paranasal Sinus Neoplasms/pathology , Paranasal Sinus Neoplasms/surgery , Paranasal Sinus Neoplasms/virology , Paranasal Sinuses/diagnostic imaging , Paranasal Sinuses/pathology , Paranasal Sinuses/surgery , Paranasal Sinuses/virology , Tomography, X-Ray Computed , Treatment Outcome
2.
Pathology
; 45(7): 693-5, 2013 12.
Article
in English
| MEDLINE
| ID: mdl-24247629