1.
J Child Neurol
; 26(3): 356-60, 2011 Mar.
Article
in English
| MEDLINE
| ID: mdl-21270471
ABSTRACT
Alexander disease is a progressive neurodegenerative disease, which can present with brainstem lesions with imaging characteristics similar to multifocal low-grade glioma, thus presenting a diagnostic dilemma. The authors report a 6-year-old child presenting with multifocal brainstem lesions subsequently diagnosed to have Alexander disease. In vivo magnetic resonance spectroscopy generated a metabolite profile of the lesion allowing differentiation from low-grade glioma. Magnetic resonance spectroscopy is a powerful tool in the assessment of brainstem lesions and is a useful adjunct to conventional magnetic resonance imaging in the assessment and diagnosis of atypical brain lesions.
Subject(s)
Alexander Disease/diagnosis , Brain Stem/pathology , Magnetic Resonance Spectroscopy/methods , Child , Female , Humans , Magnetic Resonance Imaging/methods
2.
J Pediatr Ophthalmol Strabismus
; 45(3): 190-1, 2008.
Article
in English
| MEDLINE
| ID: mdl-18524203