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1.
Acta Orthop Traumatol Turc ; 43(2): 185-9, 2009.
Article in Turkish | MEDLINE | ID: mdl-19448360

ABSTRACT

We report a 30-year-old male patient with two unicameral bone cysts (UBC) simultaneously located in the proximal third of the right femur and ipsilateral ischium ramus, respectively. Fine needle biopsies were attempted for both lesions. Biopsy of the femoral lesion under local anesthesia was unsuccessful, so an open biopsy was performed which confirmed the diagnosis of UBC. Biopsy of the ischial lesion was not sufficient for diagnosis. Cytological examination of both specimens showed no other benign or malignant pathology. The femoral lesion was treated with intralesional (due to its large size) excision-curettage, bone grafting, and the introduction of a long gamma locking intramedullary nail to prevent the occurrence of a pathological fracture. The ischial lesion was left untreated and followed conservatively. The patient was free of any symptoms and complications three years postoperatively. This is the first report of an adult patient with UBCs simultaneously located both in a long tubular bone (femur) and a flat bone (ischium ramus).


Subject(s)
Bone Cysts/pathology , Bone Cysts/therapy , Femur , Ischium , Adult , Biopsy , Bone Cysts/diagnosis , Bone Cysts/surgery , Bone Transplantation , Curettage , Femur/pathology , Femur/surgery , Fracture Fixation, Intramedullary , Humans , Male , Treatment Outcome
2.
Nucl Med Commun ; 30(6): 472-9, 2009 Jun.
Article in English | MEDLINE | ID: mdl-19357547

ABSTRACT

OBJECTIVE: To assess the outcome of yttrium-90 radiation synovectomy at 6 and 12 months in patients with knee osteoarthritis unresponsive to systematic or local medical treatment. METHODS: Consecutive patients with osteoarthritic knee pain resistant to conventional therapy and submitted to intraarticular yttrium-90 treatment because of synovial inflammation, as demonstrated by early-phase bone scintigraphy, were prospectively evaluated at 6 and/or 12 months. The assessment of the outcome of treatment was based on self-reporting of relief of knee pain limiting daily activities, measured as percentage reduction of the pretherapeutic joint discomfort with a Visual Analogue Scale. Resting and nocturnal pain also were considered, together with knee flexibility and ultrasonographic changes. RESULTS: Among a total of 97 patients, a > or =50% Visual Analogue Scale pain palliation was experienced by 64 of 90 (71.1%) patients at 6 months and 50 of 69 (72.5%) at 12 months (P = 0.992). Moreover, nocturnal and resting pain alleviation, gain in knee flexibility and regression of large joint effusions and Baker's cysts were observed in considerable proportions. In the evaluation of the outcome of treatment in 62 patients with serial assessments using a composite criterion, 42 (67.7%) versus 40 (64.5%) had a satisfactory response at 6 and 12 months, respectively (P = 0.850). The probability of a favourable therapeutic result was inversely related to the severity of radiographic joint changes. CONCLUSION: Yttrium-90 synovectomy exerts a beneficial therapeutic effect in a substantial proportion of patients with osteoarthritic knee pain and synovial inflammation, inadequately controlled by pharmacotherapy. Clinical improvement is inversely related to radiographic knee damage.


Subject(s)
Osteoarthritis, Knee/surgery , Radiosurgery , Synovectomy , Yttrium Radioisotopes/therapeutic use , Aged , Female , Follow-Up Studies , Humans , Male , Osteoarthritis, Knee/therapy , Radiosurgery/adverse effects , Safety , Time Factors , Treatment Outcome
3.
J Arthroplasty ; 23(6): 931-3, 2008 Sep.
Article in English | MEDLINE | ID: mdl-18534524

ABSTRACT

A case of spontaneous recurrent hemarthrosis--due to developed hypertrophied synovium--after total knee arthroplasty is reported. The patient was successfully treated with radiosynovectomy. The first hemorrhage occurred 18 months after the total knee arthroplasty. Several similar episodes followed over a period of 4 years. Because conservative treatment failed to control the bleeding, an arthroscopic lavage was performed, which revealed the existence of proliferative synovium. A significant part of the hypertrophic tissue was excised with the use of a thermocoagulator. However, 1 month later, another episode of hemarthrosis occurred. As a final step before reoperation, the patient was treated with intra-articular injection of ytrium 90. Eighteen months later, she remains symptom-free, is very satisfied with the result, and reports no new episode of hemarthrosis.


Subject(s)
Arthroplasty, Replacement, Knee/adverse effects , Hemarthrosis/etiology , Hemarthrosis/radiotherapy , Synovial Membrane/radiation effects , Female , Hemarthrosis/diagnosis , Humans , Hypertrophy , Middle Aged , Recurrence , Synovial Membrane/pathology , Yttrium Radioisotopes
4.
Rheumatol Int ; 29(2): 141-6, 2008 Dec.
Article in English | MEDLINE | ID: mdl-18584176

ABSTRACT

This study aimed to determine the ultrasonographic prevalence of Baker's cysts in knees with chronic osteoarthritic pain and investigate for cysts correlates and relationships with scintigraphically established synovitis. Consecutive patients with chronic osteoarthritic knee pain underwent clinical examination, X-rays, ultrasonography and early-phase bone scintigraphy. Eighty-nine Baker's cysts were detected in 328 knees with chronic osteoarthritic pain (27%), whereas one cyst was identified among the 54 non-osteoarthritic knees (2%, P<0.001). Baker's cysts were detected in 72/195 (37%) patients with knee osteoarthritis. Abnormal and intense tracer accumulation in early-phase bone scintigraphy were significantly more frequent in osteoarthritic knees with Baker's cysts (97 and 56%, respectively), than in those without (89 and 40%, respectively, P<0.05 for both). Clinical and radiographic variables could not predict the presence of those cysts. Baker's cysts are a common ultrasonographic finding in knees with chronic osteoarthritic pain and are associated with synovial inflammation and its grade.


Subject(s)
Osteoarthritis, Knee/pathology , Pain/pathology , Popliteal Cyst/diagnosis , Aged , Aged, 80 and over , Comorbidity , Female , Greece/epidemiology , Humans , Knee Joint/diagnostic imaging , Male , Middle Aged , Osteoarthritis, Knee/complications , Osteoarthritis, Knee/epidemiology , Pain/etiology , Popliteal Cyst/epidemiology , Popliteal Cyst/etiology , Prevalence , Radiography , Synovitis/complications , Synovitis/pathology , Tomography, Emission-Computed , Ultrasonography
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