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Cell ; 181(5): 1131-1145.e21, 2020 05 28.
Article in English | MEDLINE | ID: mdl-32386546

ABSTRACT

There are many unanswered questions about the population history of the Central and South Central Andes, particularly regarding the impact of large-scale societies, such as the Moche, Wari, Tiwanaku, and Inca. We assembled genome-wide data on 89 individuals dating from ∼9,000-500 years ago (BP), with a particular focus on the period of the rise and fall of state societies. Today's genetic structure began to develop by 5,800 BP, followed by bi-directional gene flow between the North and South Highlands, and between the Highlands and Coast. We detect minimal admixture among neighboring groups between ∼2,000-500 BP, although we do detect cosmopolitanism (people of diverse ancestries living side-by-side) in the heartlands of the Tiwanaku and Inca polities. We also highlight cases of long-range mobility connecting the Andes to Argentina and the Northwest Andes to the Amazon Basin. VIDEO ABSTRACT.


Subject(s)
Anthropology/methods , DNA, Ancient/analysis , Gene Flow/genetics , Central America , DNA, Mitochondrial/genetics , Gene Flow/physiology , Genetics, Population/methods , Haplotypes , Humans , Sequence Analysis, DNA , South America
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